Mitofusins Mfn1 and Mfn2 are required to preserve glucose- but not incretin-stimulated β-cell connectivity and insulin secretion by Georgiadou, Eleni, Muralidharan, Charanya, Martinez, Michelle, Chabosseau, Pauline, Akalestou, Elina, Tomas, Alejandra, Yong, Fiona Su Wern, Stylianides, Theodoros, Wretlind, Asger, Legido-Quigley, Cristina, Jones, Ben, Lopez-Noriega, Livia, Xu, Yanwen, Gu, Guoqiang, Alsabeeh, Nour, Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Ali, Yusuf, Soleimanpour, Scott A., Linnemann, Amelia K., Rodriguez, Tristan A., Rutter, Guy A.

“…Mitochondrial glucose metabolism is essential for stimulated insulin release from pancreatic β-cells. Whether mitofusin gene expression, and hence, mitochondrial network integrity, is important for glucose or incretin signaling has not previously been explored. …”
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From emissions to resources: mitigating the critical raw material supply chain vulnerability of renewable energy technologies by Mertens, Jan, Dewulf, Jo, Breyer, Christian, Belmans, Ronnie, Gendron, Corinne, Geoffron, Patrice, Goossens, Luc, Fischer, Carolyn, Du Fornel, Elodie, Hayhoe, Katharine, Hirose, Katsu, Le Cadre-Loret, Elodie, Lester, Richard, Maigné, Fanny, Maitournam, Habibou, de Miranda, Paulo Emilio Valadão, Verwee, Peter, Sala, Olivier, Webber, Michael, Debackere, Koenraad

“…The massive deployment of clean energy technologies plays a vital role in the strategy to attain carbon neutrality by 2050 and allow subsequent negative CO<jats:sub>2</jats:sub> emissions in order to achieve our climate goals. …”
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Dual Origin of Viscoelasticity in Polymer-Carbon Black Hydrogels: A Rheometry and Electrical Spectroscopy Study by Legrand, Gauthier, Manneville, Sébastien, McKinley, Gareth H., Divoux, Thibaut

“…These relaxation spectra can be rescaled onto a master curve that exhibits a power-law scaling in the high-frequency limit, with an exponent that follows Zimm theory, showing that CMC plays a key role in the gel viscoelastic properties for �>��. …”
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Protein Folding, Host Cell Proteostasis, and Viral Evolution by Yoon, Jimin

“…It follows that the host’s proteostasis network could play a prominent role in defining the sequence space accessible to an evolving viral protein. …”
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Function of second cladding layer in hollow core tube lattice fibers by Huang, Xiaosheng, Yoo, Seongwoo, Yong, KenTye

“…Modes attenuation of the tube lattice fiber (TLF) is characterized by D/λ, where D is the core diameter and λ is the wavelength. Hence, the TLF is structured with a large core to ensure a low attenuation loss. …”
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CAN communication of power converters system for aerospace application by Imam Agung Raharja

“…The project is Industrial Sponsored Project (ISP) with Rolls-Royce Singapore Pte Ltd. The project aims to design the CAN communication system for the aerospace power system from the scratch. …”
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Novel loci and biomedical consequences of iron homoeostasis variation by Allara, E, Bell, S, Smith, R, Keene, SJ, Gill, D, Gaziano, L, Morselli Gysi, D, Wang, F, Tragante, V, Mason, A, Karthikeyan, S, Lumbers, RT, Bonglack, E, Ouwehand, W, Roberts, DJ, Dowsett, J, Ostrowski, SR, Larsen, MH, Ullum, H, Pedersen, OB, Brunak, S, Banasik, K, Erikstrup, C, Mitchell, J

“…Iron homoeostasis is tightly regulated, with hepcidin and soluble transferrin receptor (sTfR) playing significant roles. However, the genetic determinants of these traits and the biomedical consequences of iron homoeostasis variation are unclear. …”

Origins and immunopathogenesis of autoimmune central nervous system disorders by Ramanathan, S, Brilot, F, Irani, SR, Dale, RC

“…First, we review non-modifiable risk factors, such as age, sex and ethnicity, as well as genetic factors such as monogenic variants, common variants in vulnerability genes and emerging HLA associations. Second, we highlight how interactions between environmental factors and epigenetics can modify disease onset and severity. …”

Epidemiology and transmission of carbapenemase-producing enterobacteriaceae in a health care network of an acute-care hospital and its affiliated intermediate- and long-term-care f... by Aung, Aung-Hein, Kanagasabai, Kala, Koh, Jocelyn, Hon, Pei-Yun, Ang, Brenda, Lye, David C., Chen, Swaine L., Chow, Angela

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Cognitive dynamic airspace management by Wong, Cheryl Sze Yin

“…Multi-objective EAs are fundamentally stochastic in nature, hence solutions are likely to be irreproducible. …”
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Deubiquitinases in muscle physiology and disorders by Olie, CS, O'Brien, DP, Jones, HBL, Liang, Z, Damianou, A, Sur-Erdem, I, Pinto-Fernández, A, Raz, V, Kessler, BM

“…Several mutations in DUB encoding genes are linked to human NMDs, such as ATXN3, OTUD7A, UCHL1 and USP14, whilst other NMDs are associated with dysregulation of DUB expression. …”

21世纪中国电影英雄的塑造 = The making of a 21st century China film hero by 佘曜丞 Seah, Walter Yao Chen

“…A hero, a great and ideal role model in the hearts of the people. From the beginning of the ancient times of worship, the image of a hero was crafted based on the times that it appears, showing that not only does a hero requires the qualities that its predecessors have, but it also must consist of the qualities that are recognized by the modern age as well. …”
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An atomtronic experimental setup for engineering quantised circulations by Gan, Koon Siang

“…Persistent currents in ring structures play an important role in Atomtronics as it forms the basis of many interesting Atomtronic systems such as ring lattices and stacked rings. …”
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Alkynone β-trifluoroborates: a new class of amine-specific biocompatible click reagents by Teng, Shenghan, Ng, Elvis Wang Hei, Zhang, Zhenguo, Soon, Chee Ning, Xu, Hailun, Li, Ruifang, Hirao, Hajime, Loh, Teck-Peng

“…Ultimately, the essential role of water during the reaction was elucidated.…”
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Evaluating slope stability using regional water balance analysis by Rangarajan, Saranya

“…Vegetations play an important role in slope stability. Hence, it is important to intervene before the wilting point of the plant is reached during extreme dry conditions. …”
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Analysis of high power gallium nitride based high electron mobility transistors for next generation electronics applications by Vompolu, Ganesh Sampath

“…The DC device characteristics and lattice temperature profiles of the AlGaN/GaN/Si HEMT have been simulated and analysed to understand the role of self-heating effects on their electrical characteristics. …”
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Meta-cognitive learning algorithm for neuro-fuzzy inference systems by Kartick Subramanian

“…For solving classification problems, class-specific information plays a vital role. Hence, McFIS has been extended to solve classification problems, efficiently, by considering class-specific information. …”
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Atypical DNA methylation, sRNA-size distribution, and female gametogenesis in Utricularia gibba by Cervantes-Pérez, Sergio Alan, Yong-Villalobos, Lenin, Florez-Zapata, Nathalia M. V., Oropeza-Aburto, Araceli, Rico-Reséndiz, Félix, Amasende-Morales, Itzel, Lan, Tianying, Martínez, Octavio, Vielle-Calzada, Jean Philippe, Albert, Victor A., Herrera-Estrella, Luis

“…The most studied DNA methylation pathway in plants is the RNA Directed DNA Methylation (RdDM), a conserved mechanism that involves the role of noncoding RNAs to control the expansion of the noncoding genome. …”
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Bacteriocin-like peptides encoded by a horizontally acquired island mediate Neisseria gonorrhoeae autolysis by Poncin, K, McKeand, SA, Lavender, H, Kurzyp, K, Harrison, OB, Roberti, A, Melia, C, Johnson, E, Maiden, MCJ, Greaves, DR, Exley, R, Tang, CM

“…Here, we searched for genes present in these 2 invasive species but not in other members of the Neisseria genus. …”

High-performance thermomagnetic generator controlled by a magnetocaloric switch by Liu, Xianliang, Chen, Haodong, Huang, Jianyi, Qiao, Kaiming, Yu, Ziyuan, Xie, Longlong, Ramanujan, Raju V., Hu, Fengxia, Chu, Ke, Long, Yi, Zhang, Hu

“…Unlike its usual role as the coil core or big magnetic yoke in previous works, here the magnetocaloric material acts as a switch that controls the magnetic circuit. …”
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