Scaling of the velocity profile in strongly drag reduced turbulent flows over an oscillating wall by Skote, Martin

“…Scaling analysis of the velocity profiles in strongly drag reduced flows reveals that the slope of the logarithmic part depends on the amount of drag reduction (DR). …”
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Eccentricity effects of microhole arrays on drag reduction efficiency of microchannels with a hydrophobic wall by Kashaninejad, Navid, Nguyen, Nam-Trung, Chan, Weng Kong

“…Subsequently, the drag reduction performance of the microchannels with such hydrophobic microhole surfaces is evaluated. …”
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Computation fluid dynamics on drag reduction II by Zang, Bin

“…Both the flow pattern in the form of velocity contours and the quantitative drag coefficient are extracted and compared in several ways: single dimple along the wall with depth (h/D = 0.21); multiple (three) dimples along the wall with different separation distances between adjacent dimples; single dimple but with several other h/D ratios (i.e. 0.25, 0.14, 0.10, 0.08). …”
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A bilayer swellable drug-eluting ureteric stent : localized drug delivery to treat urothelial diseases by Lim, Wei Shan, Chen, Kenneth, Chong, Tsung Wen, Xiong, Gordon Minru, Birch, William R., Pan, Jisheng, Lee, Bae Hoon, Er, Pei Shan, Salvekar, Abhijit Vijay, Venkatraman, Subbu S., Huang, Yingying

“…On deployment, the device swells to co-apt with the ureteric wall and ensure drug availability to these tissues. …”
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Layer-by-layer assembled micro and nano carriers for drug delivery applications by Mutukumaraswamy Shaillender

“…In nano- or microparticulate drug delivery, both control of the drug release and interaction of the particles with the cellular environment are critical attributes. …”
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Turbulent Flow over a Flexible Wall Undergoing a Streamwise Traveling Wavy Motion by Shen, Lian, Zhang, Xiang, Yue, Dick K.P., Triantafyllou, Michael S.

“…For negative c/U, we find that flow separation is enhanced and a large drag force is produced. For positive c/U, the results show that as c/U increases from zero, the separation bubble moves further upstream and away from the wall, and is reduced in strength. …”
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A bilayer swellable drug-eluting stent for the treatment of fibrosis-induced ureteral stricture recurrence by Lim, Wei Shan

“…The first layer is needed for sustained release of drug while the second layer is required for close contact with urothelial wall. …”
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Characterization and evaluation of bilayer coating for enhanced localization and sustained drug delivery for fibrosis-induced ureteral stricture by Chin, Jia Wen

“…The usage of a bilayer coating, consisting of a hydrogel layer and a drug-loaded polymer layer, allows for direct contact with the ureter walls upon swelling and drug delivery through the urothelium. …”
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Increasing antibiotic activity by rapid bioorthogonal conjugation of drug to resistant bacteria using an upconverted light-activated photocatalyst by Du, Quanchao, Wu, Xiangyang, Bi, Wuguo, Xing, Bengang, Yeow, Edwin Kok Lee

“…We demonstrate that the mode of action is due to increased inhibition of peptidoglycan cell wall biosynthesis. The findings in this study demonstrate that on-demand NIR-light activated bioorthogonal conjugation of Van to microbes is a viable alternative treatment in combating drug-resistant bacteria.…”
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Cationic glycosylated block co-β-peptide acts on the cell wall of Gram-positive bacteria as anti-biofilm agents by Zhang, Kaixi, Raju, Cheerlavancha, Zhong, Wenbin, Pethe, Kevin, Gründling, Angelika, Chan-Park, Mary B.

“…In addition to the emergence of resistance to last resort drugs, bacteria escape antibiotics killing by forming complex biofilms. …”
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Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY) by Karadzas, M

“…These screens reveal antifungal drug targets, transporters responsible for drug uptake or efflux, as well as metabolic, signalling and trafficking pathways affecting antifungal susceptibility. …”

AI is a viable alternative to high throughput screening: a 318-target study by Wallach, Izhar, Bernard, Denzil, Nguyen, Kong, Ho, Gregory, Morrison, Adrian, Stecula, Adrian, Rosnik, Andreana, O’Sullivan, Ann Marie, Davtyan, Aram, Samudio, Ben, Thomas, Bill, Worley, Brad, Butler, Brittany, Laggner, Christian, Thayer, Desiree, Moharreri, Ehsan, Friedland, Greg, Truong, Ha, van den Bedem, Henry, Ng, Ho Leung, Stafford, Kate, Sarangapani, Krishna, Giesler, Kyle, Ngo, Lien, Mysinger, Michael, Ahmed, Mostafa, Anthis, Nicholas J., Henriksen, Niel, Gniewek, Pawel, Eckert, Sam, de Oliveira, Saulo, Suterwala, Shabbir, PrasadPrasad, Srimukh Veccham Krishna, Shek, Stefani, Contreras, Stephanie, Hare, Stephanie, Palazzo, Teresa, O’Brien, Terrence E., Van Grack, Tessa, Williams, Tiffany, Chern, Ting-Rong, Kenyon, Victor, Lee, Andreia H., Cann, Andrew B., Bergman, Bastiaan, Anderson, Brandon M., Cox, Bryan D., Warrington, Jeffrey M., Sorenson, Jon M., Goldenberg, Joshua M., Young, Matthew A., DeHaan, Nicholas, Pemberton, Ryan P., Schroedl, Stefan, Abramyan, Tigran M., Gupta, Tushita, Mysore, Venkatesh, Presser, Adam G., Ferrando, Adolfo A., Andricopulo, Adriano D., Ghosh, Agnidipta, Ayachi, Aicha Gharbi, Mushtaq, Aisha, Shaqra, Ala M., Toh, Alan Kie Leong, Smrcka, Alan V., Ciccia, Alberto, de Oliveira, Aldo Sena, Sverzhinsky, Aleksandr, de Sousa, Alessandra Mara, Agoulnik, Alexander I., Kushnir, Alexander, Freiberg, Alexander N., Statsyuk, Alexander V., Gingras, Alexandre R., Degterev, Alexei, Tomilov, Alexey, Vrielink, Alice, Garaeva, Alisa A., Bryant-Friedrich, Amanda, Caflisch, Amedeo, Patel, Amit K., Rangarajan, Amith Vikram, Matheeussen, An, Battistoni, Andrea, Caporali, Andrea, Chini, Andrea, Ilari, Andrea, Mattevi, Andrea, Foote, Andrea Talbot, Trabocchi, Andrea, Stahl, Andreas, Herr, Andrew B., Berti, Andrew, Freywald, Andrew, Reidenbach, Andrew G., Lam, Andrew, Cuddihy, Andrew R., White, Andrew, Taglialatela, Angelo

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Combatting pathogenic bacteria with synthetic immunotherapeutics from chitosan: antibody recruiting at engineered bacterial surface with peptidoglycan analogs by Xu, Yuan, Song, Shihao, Duan, Hongwei, Deng, Yinyue, Liu, Xue-Wei

“…The emergence of microbial drug resistance, coupled with the paucity of new antibiotics poses an impending threat to public health. …”
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An experimental and simulation study of chip transportation behaviour in gundrilling by Tnay, Guan Leong

“…From the experiments, terminal velocities of typical gun drill chips at different range of particle Reynolds number were determined to construct the unique drag curve. Based on the findings, a computational fluid dynamic (CFD) numerical model was developed to predict the lateral drag forces with respect to the particle Reynolds number. …”
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Multi-scale and multiphase modeling of abrasive flow machining process with experimental validation by Mohamed Adel Abdelhakem Amen

“…Different from the common thought, the study proves that MR mechanism mainly comes from drag and impulse forces activated when the particle is blocked by surface asperity/protrusion…”
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Pathogen diversity and antimicrobial resistance transmission of Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study... by Dyson, ZA, Ashton, PM, Khanam, F, Chunga Chirambo, A, Shakya, M, Meiring, JE, Tonks, S, Karkey, A, Msefula, C, Clemens, JD, Dunstan, SJ, Baker, S, Dougan, G, Pitzer, VE, Basnyat, B, Qadri, F, Heyderman, RS, Gordon, MA, Holt, KE, Pollard, AJ, STRATAA Study Group

“…</p> <br> <p><strong>Funding:</strong> Wellcome Trust, Bill &amp; Melinda Gates Foundation, EU Horizon 2020, and UK National Institute for Health and Care Research.…”

Large eddy simulation of ABL flow around a parabolic concave roof model by Zulfadli Bin Abdul Latiff

“…C_P decreases on both the windward wall and leeward wall as flow velocity increases. …”
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Slow viscous flow around two particles in a cylinder by Yao, Xin, Marcos, Wong, Teck Neng

“…The two solutions are performed in an iterated framework using the method of reflections. We compute the drag force and torque coefficients of the particles which are dependent on the distances among the cylinder wall and the two particles. …”
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Investigation of phenylpropanoid sucrose esters as antidiabetic compounds by Wong, Kathy Pooi Wen

“…Since hybrid 77 is a systemic drug, dosing of the compound would have to account for both the rate at which it is transported across the gut wall and its toxicity. …”
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Utilizing food waste and thermoplastic starch (TPS) in 3D printed PLA formulations for sustainable and customizable controlled delivery systems by Wang, Liwen

“…With the addition of TPS, the drug release profile can be adjusted from 8 – 120 hours using different TPS ratios and different printed wall thicknesses. …”
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