The association of sleep duration with the risk of chronic kidney disease: a systematic review and meta-analysis by Koh, Jin Hean, Yeo, Brian Sheng Yep, Tan, Timothy Wei En, See, Mark Yong Siang, Ng, Adele Chin Wei, Loh, Shaun Ray Han, Gooley, Joshua, Tan, Chieh Suai, Toh, Song Tar

“…In total, 42 studies (2 613 971 patients) with a mean age of 43.55 ± 14.01 years were included in the meta-analysis. Compared with a reference range of 7 to 8 hours of sleep, short sleep durations of ≤4 hours (RR 1.41, 95% CI: 1.16 to 1.71, P < 0.01), ≤5 hours (RR 1.46, 95% CI: 1.22 to 1.76, P < 0.01), ≤6 hours (RR 1.18, 95% CI: 1.09 to 1.29, P < 0.01), and ≤7 hours (RR 1.19, 95% CI: 1.12 to 1.28, P < 0.01) were significantly associated with an increased risk of incident chronic kidney disease. …”
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BSACI guidance for the implementation of Palforzia® peanut oral immunotherapy in the United Kingdom: a Delphi consensus study by Marrs, Tom, Patel, Nandinee, Burrell, Sarah, Rampersad, Anjali, Minshall, Eleanor, Leech, Susan, Chandratilleke, Dinusha, Dempsey, Justine, Ludman, Sian, Roberts, Graham, Michaelis, Louise Jane, Brough, Helen A., Karanam, Surendra, Batt, Rebecca, Moulsdale, Phoebe, Steifel, Gary, Tiwana, Kiran, Smith, Helen, Knight, Katherine, Vazquez-Ortiz, Marta, Vyas, Deepan, Turner, Paul J., Makwana, Nick

“…These guidance statements will be adapted in the coming years as more evidence is published and as the international experience of peanut immunotherapy evolves.…”
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闽西北农村环境污染对闽江水质影响的研究 = Effect of agricultural pollutants in north-west Fujian Province on Ming Jiang water quality by 游诗祥 You, Shixiang, 黄月珍 Huang, Yuezhen, 吴成城 Wu, Chengcheng

“…In this paper, clean the county as the representative from the rural farming, aquaculture and living pollution analysis of three aspects of environmental pollution in rural northwestern Fujian, the main pollutants that the rural northwest of Fujian is COD, total phosphorus, total nitrogen three categories, and through infiltration of surface runoff or underground into the Minjiang River; the same time, exceeding the water quality of Minjiang River over the years and found that the number exceeded 51%, 57% of types of pollutants and pollution in rural areas northwest of Fujian.…”
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Development of the CHARIOT Research Register for the Prevention of Alzheimer’s Dementia and Other Late Onset Neurodegenerative Diseases by Larsen, Mark E., Curry, Lisa, Mastellos, Nikolaos, Robb, Catherine, Car, Josip, Middleton, Lefkos T.

“…Invitations were posted to individuals aged between 60 and 85 years, without a diagnosis of dementia. Upon consent, a minimum data set of demographic and contact details was extracted from the patient’s electronic health record. …”
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Infections diagnosed in children and young people screened for malaria in UK emergency departments: a retrospective multi-centre study by Bird, C, Hayward, GN, Turner, PJ, Wasala, D, Merrick, V, Lyttle, MD, Mullen, N, Fanshawe, TR

“…</p> <br> <p><strong>Methods:</strong> This is a retrospective, multi-centre, observational study nested in a diagnostic accuracy study for malaria rapid diagnostic tests. Any CYP less than 16 years presenting to a participating ED with a history of fever and travel to a malaria-endemic area between 1 January 2016 and 31 December 2017 and who had a malaria screen as a part of standard care were included. …”

Using feminist methodologies to explore female genital mutilation/cutting and child marriage in low- and middle-income contexts by Jones, N, Pincock, K, Alheiwidi, S

“…Eliminating harmful practices, which are rooted in gender inequality and have myriad life-course consequences for those who experience them, has become a global priority in recent years. However, dominant conceptualizations of the drivers and consequences of child marriage and FGM/C often fail to adequately engage with or reflect adolescent girls' own nuanced experiences and perceptions. …”

Mechanistic insights into the HPF1/PARP1 complex by Zobel, FFH

“…While PARP1 was originally described to modify target substrates on glutamate and aspartate sites, it has become apparent in recent years that the presence of another protein, histone PARylation factor 1 (HPF1), switches its preference to serine target sites. …”

HLA-DQB1*05 subtypes and not DRB1*10:01 mediates risk in anti-IgLON5 disease by Yogeshwar, SM, Muñiz-Castrillo, S, Sabater, L, Peris-Sempere, V, Mallajosyula, V, Luo, G, Yan, H, Yu, E, Zhang, J, Lin, L, Fagundes Bueno, F, Ji, X, Picard, G, Rogemond, V, Pinto, AL, Heidbreder, A, Höftberger, R, Graus, F, Dalmau, J, Santamaria, J, Iranzo, A, Schreiner, B, Giannoccaro, MP, Liguori, R, Shimohata, T, Kimura, A, Ono, Y, Binks, S, Mariotto, S, Dinoto, A, Bonello, M, Hartmann, CJ, Tambasco, N, Nigro, P, Prüss, H, McKeon, A, Davis, MM, Irani, SR, Honnorat, J, Gaig, C, Finke, C, Mignot, E

“…This association was further reflected in an increasingly later age of onset across each genotype group, with a delay of up to 11 years, while HLA-DQ-dosage dependent effects were also suggested by reduced risk in the presence of non-predisposing DQ1 alleles. …”

Experiences, perceptions and ethical considerations of the malaria infection study in Thailand by Naemiratch, B, Kulpijit, N, Ruangkajorn, S, Day, NPJ, Prachumsri, J, Cheah, PY

“…However, due to cross-border movements over the past 5 years, reported malaria cases in Thailand have risen. …”

Self-supervised machine learning to characterise step counts from wrist-worn accelerometers in the UK Biobank by Small, SR, Chan, S, Walmsley, R, von Fritsch, L, Acquah, A, Mertes, G, Feakins, BG, Creagh, A, Strange, A, Matthews, CE, Clifton, DA, Price, AJ, Khalid, S, Bennett, D, Doherty, A

“…Our data indicate an inverse dose-response association, where taking 6,430-8,277 daily steps was associated with 37% [25-48%] and 28% [20-35%] lower risk of fatal CVD and all-cause mortality up to seven years later, compared to those taking fewer steps each day.…”

Validating the ratio of insulin like growth factor binding protein 4 to sex hormone binding globulin as a prognostic predictor of preterm birth in Viet Nam: a case-cohort study by Hirst, JE, Boniface, JJ, Le, DP, Polpitiya, AD, Fox, AC, Vu, TTK, Dang, TT, Fleischer, TC, Bui, NTH, Hickok, DE, Kearney, PE, Thwaites, G, Kennedy, SH, Kestelyn, E, Le, TQ

“…Optimal performance (AUC 0.74) was seen within 19-20 weeks’ gestation, for BMI &gt;21 kg/m2 and age 20-35 years. <p><strong> Conclusion</strong></p> We have validated a novel serum biomarker for PTB risk stratification in a very different setting to the original study. …”

Multicenter double-blind study evaluating AI-driven detection of proximal deep vein thrombosis by Curry, N, Allen, E, Silsby, L, Goodacre, S, Deane, C, Deary, A, Foster, A, Griffiths, J, Sharma, R, Thomas, H, Mischewitz, S, Al-Noor, F

“…</p> <br> <p><strong>Methods:</strong> Eleven regional hospital DVT diagnostic clinics enrolled adult patients, 18 years of age or older, who were referred for investigation of symptoms suggestive of DVT, including a compression ultrasound. …”

Associations between snoring, body mass index and coronary artery diseases: observational and mendelian randomization study in Asia by Zhu, Y, Lan, Y, Lv, J, Sun, D, Pei, P, Yang, L, Millwood, IY, Walters, RG, Chen, Y, Du, H, Wang, J, Yang, X, Stevens, R, Chen, J, Chen, Z, Li, L, Yu, C

“…<p><strong>Results</strong></p> During a median follow-up of 12.32 years, 48,997 participants developed CAD. Snoring and habitual snoring were associated with incident CAD and myocardial infarction (MI), habitual snoring was also associated with stable angina pectoris (SAP). …”

May measurement month 2022: an analysis of blood pressure screening findings from Sierra Leone by Jalloh, MB, Williams, CEE, Jegede, OG, Malijan, GMB, Naveed, A, Kanu, A, Bah, AK, Jalloh, F, Jalloh, A, Faulkner, MMJ, Agboola, K, Baldeh, M, Russell, JBW, Oladapo, OO

“…Results: Among the participants (mean age 38.0 years, predominantly Black), the prevalence of hypertension was 25.7% (210 out of 818 participants). …”

Frailty, multimorbidity and polypharmacy: exploratory analyses of the effects of empagliflozin from the EMPA-KIDNEY trial by Mayne, KM, Sardell, R, Staplin, N, Judge, P, Zhu, D, Sammons, E, Wanner, C, Emberson, J, Preiss, D, Landray, M, Baigent, C, Haynes, R, Herrington, W

“…</p> <br> <p><strong>Methods:</strong> The EMPA-KIDNEY trial randomized 6609 patients with CKD (estimated glomerular filtration rate [eGFR] ≥20<45 mL/min/1.73m2 , or ≥45<90 mL/min/1.73m2 with urinary albumin-to-creatinine ratio ≥200 mg/g) to receive either empagliflozin 10 mg daily or matching placebo and followed for two years (median). Additional characteristics analysed in subgroups were multimorbidity, polypharmacy and health-related quality of life (HRQoL) at baseline. …”

The geomorphic work of the European mole (Talpa europaea): long-term monitoring of molehills using structure-from-motion photogrammetry by Baxter, T, Woor, S, Coombes, M, Viles, H

“…</em><em>europaea</em> over larger spatial scales (e.g. river catchments) and longer timescales (e.g. years‒decades) to determine its importance in relation to other bioturbators and within the wider sediment system.…”

The mediating role of health literacy between the presence of chronic disease and psychological distress among older persons in Xian City of China by Guo, Kun, Ouyang, Jing, Minhat, Halimatus Sakdiah

“…Methods: This study employs a quantitative research design using a cross-sectional survey of 300 older persons over 60 years living in the six urban districts of Xi’an city. …”
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Distributed consensus of second-order multi-agent systems by Yu, Zhong

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Mastering Voice Interfaces : Creating Great Voice Apps for Real Users / by Thymé-Gobbel, Ann, author 642940, Jankowski, Charles, author 642941

“…We start with the basics of voice interfaces, and how they are different from others, then dive into basic design principles that we're learned in many years building these apps in the industry. As we cover a design principle, we'll also demonstrate how to implement it with one of the established voice platforms (Google Home), and show how, though the tools are great, you don't have to go too far to have to do some custom work to get what you really want. …”

Low-Cost Electronic Microfluidics for Multiplexed Point-of-Care Biomarker Detection by Kikkeri, Kruthika

“…As we have seen in recent years, point-of-care (PoC) systems are vital elements in healthcare, as they can aid in disease detection, monitoring, and treatment, and even inform public policy. …”
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