CRISPR/Cas9 RNP-assisted validation of palmarumycin biosynthetic gene cluster in Lophiotrema sp. F6932 by Gakuubi, Martin Muthee, Ching, Kuan Chieh, Munusamy, Madhaiyan, Wibowo, Mario, Lim, Chun Teck, Ma, Guang-Lei, Liang, Zhao-Xun, Kanagasundaram, Yoganathan, Ng, Siew Bee

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Metal-free σ-bond metathesis in 1,3,2-diazaphospholene-catalyzed hydroboration of carbonyl compounds by Chong, Che Chang, Hirao, Hajime, Kinjo, Rei

“…Kinetic and computational studies suggest that the σ-bond metathesis occurred in a stepwise but nearly concerted manner.…”
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A decade after the first full human genome sequencing : when will we understand our own genome? by Eisenhaber, Frank

“…The promises with regard to medical cures and biotechnology applications have been realized not even nearly to the expectations. Understanding the human genomes means knowing the genes' and proteins' functions and their interconnectedness via biomolecular mechanisms. …”
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Culture of human pluripotent stem cells and neural networks in 3D using an optogenetic approach and a hydrogel model by Lee, S

“…Expression of ChR2-YFP was found driven by both SYN1 and CaMKII promoter in the RGD-alginate bead system that cultured with Axol cells.</p>…”

On propagation characteristics of ultrasonic guided waves in helical strands by Zhang, Hongyan, Li, Jian, Jiang, Can, Chen, Shili, Fan, Zheng, Liu, Yang

“…Steel strands have been widely used in industrial fields as a reliable load-bearing component. Under the influence of environmental erosion and fatigue stress, different types of damage, such as corrosion and fracture, will occur in the in-service steel strands, which will cause unpredictable loss of personnel and property. …”
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Maneuvering angle rigid formations with global convergence guarantees by Chen, Liangming, Lin, Zhiyun, De Marina, Hector Garcia, Sun, Zhiyong, Feroskhan, Mir

“…Angle rigid multi-agent formations can simultaneously undergo translational, rotational, and scaling maneuvering, therefore combining the maneuvering capabilities of both distance and bearing rigid formations. However, maneuvering angle rigid formations in 2D or 3D with global convergence guarantees is shown to be a challenging problem in the existing literature even when relative position measurements are available. …”
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Influence of operating parameters on morphology of laser hardened surfaces by Maharjan, Niroj, Zhou, Wei, Zhou, Yu, Wu, Naien

“…Laser transformation hardening is an attractive heat treatment technology which can be used to enhance the surface properties of highly stressed components such as cams, gears, and bearings without altering its bulk properties. The highly intense laser beam rapidly heats up the irradiated surface above its austenitization temperature which cools down instantaneously (self-quenching) as the laser moves away from the spot producing a hardened surface. …”
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Total Synthesis of Verticillin A and Application of Diazene-Directed Fragment Assembly to the Synthesis of Heterodimeric Epidithiodiketopiperazine Derivatives by Knauss, Walker

“…This is the first application of diazene-directed coupling to the synthesis of dimeric diketopiperazine alkaloids Our group’s initial route to heterodimeric ETP derivatives relied upon reductive cobalt dimerization, which produces a nearly statistical mixture of homo- and heterodimeric products. …”
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The fabrication and characterization of double waveguide ridge terahertz quantum cascade laser by Li, Jinghao

“…The double-metal waveguide is a most widely-used scheme, which can realize a nearly 100% modal confinement. The ability to make a double-metal based waveguide ridge laser is very useful. …”
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Shape-morphing structures based on perforated kirigami by Zhang, Yunlan, Yang, Jingyi, Liu, Mingchao, Vella, Dominic

“…We also examine the loading-bearing capacity of morphed structures via indentation tests in both FEM simulations and experiments. …”
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Novel bisisoquinolines : synthesis, resolution and application in asymmetric Henry reaction by Yao, Qiong Ji

“…(R)-N-alkyl-C1-1’,2’,3’,4’-terahydro-1,1’-bisisoquinoline differing in the steric bulkiness were successfully afforded to be examined in the asymmetric Henry reaction. The ligand bearing the smallest substituent was proved to be the most effective one in the CuI-catalyzed addition of nitromethane, nitroethane and nitropropane to aldehydes. …”
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Diffuse Correlation Spectroscopy (DCS) and Diffuse Optical Spectroscopy (DOS) for photodynamic therapy monitoring. by Siti Raudhah Matyasir.

“…The aim is to evaluate the relative tissue oxygen saturation (rStO2) and relative blood flow (rBF) of the tumour-bearing mice obtained from Diffuse Optical Spectroscopy (DOS) and Diffuse Correlation Spectroscopy (DCS) respectively in order to see if they have prognostic value in predicting tumour response. …”
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Nb and Ta intracrustal differentiation during granulite-facies metamorphism: evidence from geochemical data of natural rocks and thermodynamic modeling by Huang, G, Chen, Y, Guo, J, Palin, R, Zhao, L

“…However, residual crustal-derived A2-Type granites that experience significant fractionation of Nb-or Ta-bearing minerals during crystallization or contamination from other low-Nb/Ta sources cannot retain this high-Nb/Ta ratio, even though these ratios are generally higher than that of S-Type granites. …”

Role of posttranslational modifications of histone proteins in epigenetics by Raj, R

“…Using a "Tag-and-modify" approach, modified histone proteins bearing both modifications was synthesized, and was later used for nucleosome reconstitution. …”

Functional genetics of cancer and congenital disorders by Zak, J

“…An integrative analysis of cancer genomic data revealed that <em>PPP1R13B</em>, encoding ASPP1, bears many hallmarks of a tumour suppressor gene, despite being mutated at a low absolute frequency. …”

Dental resin monomer enables unique NbO2/carbon lithium-ion battery negative electrode with exceptional performance by Ji, Q, Gao, X, Zhang, Q, Jin, L, Wang, D, Xia, Y, Yin, S, Xia, S, Hohn, N, Zuo, X, Wang, X, Xie, S, Xu, Z, Ma, L, Chen, L, Chen, G, Zhu, J, Hu, B, Müller-Buschbaum, P, Bruce, PG, Cheng, L

“…The results suggest that the NbO2/carbon nanohybrid bearing high capacity, long cycle life and low gas-evolution is promising for lithium storage applications.…”

Targeting c-Met for endoscopic detection of dysplastic lesions within Barrett’s esophagus using EMI-137 fluorescence imaging by Huang, Y-J, Rieder, J, Tan, KV, Tenditnaya, A, Vojnovic, B, Gorpas, D, Quante, M, Vallis, KA

“…EMI-137 was tested in a dual xenograft mouse model bearing OE33 (c-MET high expression) and FLO-1 (c-MET low expression) tumors. …”

Modelling and integrating of experimental analysis for predicting the parameters of kenaf fibre-reinforced concrete beam-column joint by Ayeni, Ige Samuel, Mohamad Jamaludin, Yatim, Abdul Shukor Lim, Nor Hasanah

“…The intricate interactions between material composition, geometrical factors, and load-bearing capacities make it difficult to optimise the design of structural parameters of KFRC beam-column joints. …”
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Social Media Marketing Adoption among SMEs in Malaysia and Nigeria (S/O 14089) by Ramanchandram, Rajoo, Abdullah, Shahmir Sivaraj, Kolandaisamy, Indraah, Soo, Hooi Sin, Mohd Jani, Mohamad Yusop

“…It is not surprising that the relevant factors above have a strong bearing in both Malaysia and Nigeria even though they are continents apart. …”
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Influence of Fe₂O₃ and bacterial biofilms on Cu(II) distribution in a simulated aqueous solution: a feasibility study to sediments in the Pearl River Estuary (PR China) by Kurniawan, Tonni Agustiono, Lo, Waihung, Othman, Mohd Hafiz Dzarfan, Liang, Xue, Goh, Hui Hwang, Chew, Kit Wayne

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