Disruption of seasonal influenza circulation and evolution during the 2009 H1N1 and COVID-19 pandemics in Southeastern Asia by Chen, Z, Tsui, JL, Cai, J, Su, S, Viboud, C, du Plessis, L, Lemey, P, Kraemer, MUG, Yu, H

“…During the COVID-19 pandemic, consistent autumn-winter movement waves from Southeastern Asia to temperate regions were interrupted for both subtype/lineages, however the A/H1N1 pandemic only disrupted A/H3N2 spread. …”

‘The plural of silo is not ecosystem’: qualitative study on the role of innovation ecosystems in supporting ‘internet of things’ applications in health and care by Reidy, C, A’Court, C, Jenkins, W, Jani, A, Ramos, A, Morys-Carter, M, Papoutsi, C

“…We sought to examine the multiple interacting influences on IoT implementation, spread and scale-up, including the role of regional innovation ‘ecosystems’ and the impact of the COVID-19 context.…”

Ethical issues surrounding access to care for BRCA mutations by Huang, C

“…I conclude that whilst most problematic cases are country-neutral, only US women are problematically constrained by insurance and legal loopholes, and only UK women are problematically constrained by regional variations in health authority funding.</p>…”

Phenotypic screen of sixty-eight colorectal cancer cell lines identifies CEACAM6 and CEACAM5 as markers of acid-resistance by Michl, J, White, B, Monterisi, S, Bodmer, W, Swietach, P

“…Thus, CEACAM6 is a marker of acid-resistant clones in colorectal cancer and a potential motif for targeting therapies to acidic regions within the tumors. …”

Non-stationary modeling of seasonal precipitation series in Turkey: estimating the plausible range of seasonal extremes by Tosunoglu, F, Slater, LJ, Kowal, KM, Gu, X, Yin, J

“…The NAOI appeared as another important predictor during all seasons except summer, while the SOI appeared as a significant explanatory variable in certain regions. Using the non-stationary models, we then computed seasonal precipitation estimates for different return periods (i.e., 20, 50, and 100 years) and considered the minimum and maximum possible extreme precipitation scenarios at each site. …”

Information learning bias in depression by Lin, W

“…Using a similar volatility adaptation model, we then showed that loss learning rate adaptation estimates negatively correlated with individual differences in overall negativity levels (depression and anxiety), with might be associated with decreased segregation of win and loss volatility signals in a distributed brain network of outcome sensitive regions, especially in the ACC. Finally, we showed that manipulating norepinephrine level using an antidepressant, reboxetine, a norepinephrine reuptake inhibitor (NRIs), could increase loss learning rate adaptations to volatility. …”

The potential of eight plasma proteins as biomarkers in redefining leptospirosis diagnosis by Fish-Low, Cheng-Yee, Than, Leslie Thian Lung, Ling, King-Hwa, Sekawi, Zamberi

“…Leptospirosis, a notifiable endemic disease in Malaysia, has higher mortality rates than regional dengue fever. Diverse clinical symptoms and limited diagnostic methods complicate leptospirosis diagnosis. …”

An analysis of pedestrian preferences for wayfinding signage in urban settings: evidence from Nanning, China by Zhou, Jialu, Ujang, Norsidah

“…As global urbanization accelerates, the integration, readability, and connectivity of urban spaces are becoming focal points of international concern, particularly in rapidly developing regions like Asia. The inadequacies of urban wayfinding systems directly affect pedestrians’ wayfinding experiences within city spaces. …”
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The impact of the digital economy on industrial structure upgrading and sustainable entrepreneurial growth by Deevi, Durga Praveen, Allur, Naga Sushma, Dondapati, Koteswararao, Chetlapalli, Himabindu, Kodadi, Sharadha, Perumal, Thinagaran

“…The paper’s statistical foundation has been data collected from 25 Chinese regions between 2014 and 2022. The findings support that the DE’s growth positively impacts the ISU. …”

Enhancing construction site performance through technology and management practices as material waste mitigation in the Malaysian construction industry by Mohammed Abdullah Abkar, Mahdi, Yunus, Riduan, Gamil, Yaser, Albaom, Mohammed Abdo

“…The geographical specificity adds depth to the analysis, offering a comprehensive understanding of regional dynamics. Despite acknowledging limitations in technology and material usage, the study offers recommendations for refining waste mitigation and improving construction site performance. …”
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Computational modeling of low-density lipoprotein accumulation at the carotid artery bifurcation after stenting by Nasrul Hadi, Johari, Menichini, Claudia, Hamady, Mohamad S., Xu, Xiaoyun

“…Restenosis typically occurs in regions of low and oscillating wall shear stress, which also favor the accumulation of atherogenic macromolecules such as low-density lipoprotein (LDL). …”
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Energizing solar still efficiency with eco-friendly coconut shell biochar enhanced organic phase change material by Rajamony, Reji Kumar, Suraparaju, Subbarama Kousik, Kalidasan, B., Yadav, Aman, Kumar Pandey, Adarsh Kumar, Nurhanis Sofiah, Abd Ghafar, Siaw Paw, Johnny Koh, Fatehmulla, Amanullah, Samykano, Mahendran, Saidur, Rahman Md

“…These findings underscore the scalability and practical applicability of the proposed system, positioning it as a sustainable, cost-efficient, and adaptable solution for clean water production in water-scarce regions globally.…”
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Coloration and functionalization of organic cotton fabric using Chinese fringe leaf extraction: A greener approach by Hossain, Md Shazzat, Ullah, Mohammad, Mia, Rony, Assiri, Mohammed Ail, Zhou, Yahui, Saeed, Haroon A.M., Mahmud, Sakil

“…The dyed OCF also demonstrated superior UV protection, with an Ultraviolet Protection Factor (UPF) value of 59.19 ± 1.82, and minimal UV transmission in the UV−A and UV−B regions. Despite a slight reduction in air permeability compared to the undyed OCF, the dyed OCF maintained good breathability. …”
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Deep reinforcement learning for adaptive mesh refinement by Foucart, Corbin, Charous, Aaron, Lermusiaux, Pierre F.J.

“…Finite element discretizations of problems in computational physics often rely on adaptive mesh refinement (AMR) to preferentially resolve regions containing important features during simulation. …”
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Predicted Losses of Sulfur and Selenium in European Soils Using Machine Learning: A 2 Call for Prudent Model Interrogation and Selection by Jones, Gerrad D., Insinga, Logan, Droz, Boris, Feinberg, Aryeh, Stenke, Andrea, Smith, Jo, Smith, Pete, Winkel, Lenny H. E.

“…Both elements exhibited similar spatial patterns with predicted gains in Scandinavia versus losses in the central and Mediterranean regions of Europe, respectively, by the end of the 21st century for an extreme climate scenario. …”
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Unexpected anthropogenic emission decreases explain recent atmospheric mercury concentration declines by Feinberg, Aryeh, Selin, Noelle E., Braban, Christine F., Chang, Kai-Lan, Custódio, Danilo, Jaffe, Daniel A., Kyllönen, Katriina, Landis, Matthew S., Leeson, Sarah R., Luke, Winston, Molepo, Koketso M., Murovec, Marijana, Nerentorp Mastromonaco, Michelle G., Aspmo Pfaffhuber, Katrine, Rüdiger, Julian, Sheu, Guey-Rong, St. Louis, Vincent L.

“…Using linear mixed effects modeling of observational data from 51 stations, we find negative Hg0 trends in most NH regions, with an overall trend for 2005 to 2020 of −0.011 ± 0.006 ng m−3 y−1 (±2 SD). …”
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Rapid taqman-based quantification of chlorophyll d-containing cyanobacteria in the genus acaryochloris by Behrendt, Lars, Nielsen, Jeppe L., Sørensen, Søren J., Larkum, Anthony W. D., Winther, Jakob R., Kühl, Michael

“…When used on complex natural communities, the TaqMan assay detected the presence of Acaryochloris species in four out of eight samples of crustose coralline algae (CCA), collected from temperate and tropical regions. In three out of these TaqMan-positive samples, the presence of Chl d was confirmed via high-performance liquid chromatography (HPLC), and corresponding cell estimates of Acaryochloris species amounted to 7.6 × 101 to 3.0 × 103 per mg of CCA. …”
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Comparative systems biology analysis to study the mode of action of the isothiocyanate compound iberin on pseudomonas aeruginosa by Givskov, Michael, Nielsen, Thomas E., Tolker-Nielsen, Tim, Tan, Sean Yang-Yi, Liu, Yang, Chua, Song Lin, Vejborg, Rebecca Munk, Jakobsen, Tim Holm, Chew, Su Chuen, Li, Yingying, Yang, Liang

“…RNA sequencing-based transcriptomics showed that iberin inhibits the expression of the GacA-dependent small regulatory RNAs RsmY and RsmZ; this was verified by using gfp-based transcriptional reporter fusions with the rsmY or rsmZ promoter regions. Isobaric tags for relative and absolute quantitation (iTRAQ) proteomics showed that iberin reduces the abundance of the LadS protein, an activator of GacS. …”
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Viroporin activity of the foot-and-mouth disease virus non-structural 2B protein by Ao, Da, Guo, Hui-Chen, Sun, Shi-Qi, Sun, De-Hui, Fung, To Sing, Wei, Yan-Quan, Han, Shi-Chong, Yao, Xue-Ping, Cao, Sui-Zhong, Liu, Ding Xiang, Liu, Xiang-Tao

“…An analysis of the FMDV 2B protein domains by computer-aided programs conducted in this study revealed that this protein may contain two transmembrane regions. Further biochemical, biophysical and functional studies revealed that the protein possesses a number of features typical of a viroporin when it is overexpressed in bacterial and mammalian cells as well as in FMDV-infected cells. …”
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DNA-Methylation Patterns in Trisomy 21 Using Cells from Monozygotic Twins by Sailani, M. Reza, Santoni, Federico A., Letourneau, Audrey, Borel, Christelle, Makrythanasis, Periklis, Hibaoui, Youssef, Popadin, Konstantin, Bonilla, Ximena, Guipponi, Michel, Gehrig, Corinne, Vannier, Anne, Carre-Pigeon, Frederique, Feki, Anis, Nizetic, Dean, Antonarakis, Stylianos E.

“…Reduced Representation Bisulfite Sequencing (RRBS) revealed 35 differentially methylated promoter regions (DMRs) (Absolute methylation differences = 25%, FDR < 0.001) in MZ twins discordant for T21 that have also been observed in comparison between unrelated normal and T21 individuals. …”
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