Distinctive antibody responses to Mycobacterium tuberculosis in pulmonary and brain infection by Spatola, M, Nziza, N, Irvine, EB, Cizmeci, D, Jung, W, Van, LH, Nhat, LTH, Ha, VTN, Phu, NH, Nghia, HDT, Thwaites, GE, Lauffenburger, DA, Fortune, S, Thuong, NTT, Alter, G

“…<br> Using a high throughput systems serology approach, we deeply profiled the antibody responses against 10 different <i>M. tuberculosis</i> antigens, including lipoarabinomannan (LAM) and purified protein derivative (PPD), in HIV-negative adults with pulmonary TB (n = 10) versus TBM (n = 60). …”

Vitamin B12 ameliorates the pathological phenotypes of multiple Parkinson’s disease models by alleviating oxidative stress by Wu, Yue, Zhao, Zhongting, Yang, Naidi, Xin, Chenqi, Li, Zheng, Xu, Jiajia, Ma, Bo, Lim, Kah-Leong, Li, Lin, Wu, Qiong, Yu, Changmin, Zhang, Chengwu

“…Parkinson's disease (PD) is the second most common neurodegenerative disease characterized by progressive loss of dopaminergic neurons in the substantia nigra of the midbrain. The etiology of PD has yet to be elucidated, and the disease remains incurable. …”
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Opportunities for machine learning to accelerate halide-perovskite commercialization and scale-up by Kumar, Rishi E., Tiihonen, Armi, Sun, Shijing, Fenning, David P., Liu, Zhe, Buonassisi, Tonio

“…In this perspective, we review practical challenges hindering the commercialization of halide perovskites, and discuss how machine-learning (ML) tools could help: (1) active-learning algorithms that blend institutional knowledge and human expertise could help stabilize and rapidly update baseline manufacturing processes; (2) ML-powered metrology, including computer imaging, could help narrow the performance gap between large- and small-area devices; and (3) inference methods could help accelerate root-cause analysis by reconciling multiple data streams and simulations, focusing research effort on areas with highest probability for improvement. …”
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Measurement of buried undercut structures in microfluidic devices by laser fluorescent confocal microscopy by Li, Shiguang, Liu, Jing, Nguyen, Nam-Trung, Fang, Zhong Ping, Yoon, Soon Fatt

“…Measuring buried, undercut microstructures is a challenging task in metrology. These structures are usually characterized by measuring their cross sections after physically cutting the samples. …”
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Digital wavefront recording, reconstruction and 3D display by Qian, Kemao

“…The importance of the project is from the fact that phase of optical wavefronts are more important in precision metrology, though we sense the amplitude of optical wavefronts every day. …”
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White light single-shot interferometry with colour CCD camera for optical inspection of microsystems by Upputuri, Paul Kumar, Pramanik, Manojit, Nandigana, Krishna Mohan, Prasad, Mahendra

“…White light interferometry is a well-established optical tool for surface metrology of reflective samples. In this work, we discuss a single-shot white light interferometer based on single-chip color CCD camera and Hilbert transformation. …”
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Dynamic characterization of MEMS diaphragm using time averaged in-line digital holography by Miao, Jianmin, Singh, Vijay Raj, Wang, Zhihong, Hegde, Gopalkrishna M., Anand, Asundi

“…A simple and robust tool for dynamic optical metrology of MEMS devices and micro-objects using time averaged in-line digital holography is thus proposed.…”
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Multipsychiatric comorbidity in people with epilepsy compared with people without epilepsy: a systematic review and meta-analysis by Kwon, C-S, Rafati, A, Gandy, M, Scott, A, Newton, CR, Jette, N

Giant photonic spin Hall effect empowered by polarization-dependent quasibound states in the continuum in compound grating waveguide structures by Wu, Feng, Liu, Tingting, Long, Yang, Xiao, Shuyuan, Chen, Gengyan

“…The photonic spin Hall effect (PSHE) plays an important role in both fundamental science and precision metrology. In this paper, we theoretically propose a polarization-dependent bound state in the continuum (BIC) in a compound grating waveguide structure based on the selectable guided resonance at near-infrared wavelengths. …”
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From 2D to 3D: development of monolayer dopaminergic neuronal and midbrain organoid cultures for Parkinson's disease modeling and regenerative therapy by Yeap, Yee Jie, Tng, Teddy J. W., Lee, Mok Jung, Goh, Micaela, Lim, Kah-Leong

“…Despite intensive research, the etiology of PD is currently unresolved, and the disease remains incurable. …”
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PARP1 resolves DNA replication defects in PCNA-associated DNA repair disorder by Wang, L

“…</p> <p>Overall, these data have implications both for the etiology of PCNA-associated repair disorder as well as suggesting novel circumstances in which PARP-inhibition might be of use in the cancer clinic. …”

Review of mid-infrared mode-locked laser sources in the 2.0 μ m–3.5 μ m spectral region by Ma, Jie, Qin, Zhipeng, Xie, Guoqiang, Qian, Liejia, Tang, Dingyuan

“…These achievements open new opportunities for applications in areas such as molecular spectroscopy, frequency metrology, material processing, and medical diagnostics and treatment. …”
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Expediting treatments in the 21st century: orphan drugs and accelerated approvals by Domike, Reuben, Raju, G. K., Sullivan, Jamie, Kennedy, Annie

“…The re-use of surrogate markers for oncological diseases has been an advantage in a way that may not be scientifically feasible in many other disease areas that have greater differentiation across disease etiology. For non-oncological diseases, applicability of AA is, in part, dependent upon greater focus on characterization and acceptance of novel surrogate markers.…”
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First international conference on RASopathies and neurofibromatoses in Asia : identification and advances of new therapeutics by Rauen, Katherine A, Alsaegh, Abeer, Ben-Shachar, Shay, Berman, Yemima, Blakeley, Jaishri, Cordeiro, Isabel, Elgersma, Ype, Evans, D Gareth, Fisher, Michael J, Frayling, Ian M, George, Joshi, Huson, Susan M, Kerr, Bronwyn, Khire, Uday, Korf, Bruce, Legius, Eric, Messiaen, Ludwine, van Minkelen, Rick, Nampoothiri, Sheela, Ngeow, Joanne, Parada, Luis F, Phadke, Shubha, Pillai, Ashok, Plotkin, Scott R, Puri, Ratna, Raji, Anup, Ramesh, Vijaya, Ratner, Nancy, Shankar, Suma P, Sharda, Sheetal, Tambe, Anant, Vikkula, Miikka, Widemann, Brigitte C, Wolkenstein, Pierre, Upadhyaya, Meena

“…Due to their common underlying pathogenetic etiology, all these syndromes have significant phenotypic overlap of which one common feature include a predisposition to tumors, which may be benign or malignant. …”
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Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging by Baik, Sang-Ha, Selvaraji, Sharmelee, Fann, David Y., Poh, Luting, Jo, Dong-Gyu, Herr, Deron R., Zhang, Shenpeng R., Kim, Hyun Ah, Silva, Michael De, Lai, Mitchell K. P., Chen, Christopher Li- Hsian, Drummond, Grant R., Lim, Kah-Leong, Sobey, Christopher G., Arumugam, Thiruma V.

“…Vascular dementia (VaD) is a progressive cognitive impairment of vascular etiology. VaD is characterized by cerebral hypoperfusion, increased blood-brain barrier permeability and white matter lesions. …”
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Remote digital cognitive assessment reveals cognitive deficits related to hippocampal atrophy in autoimmune limbic encephalitis: a cross-sectional validation study by Shibata, K, Attaallah, B, Tai, X-Y, Trender, W, Hellyer, PJ, Hampshire, A, Irani, SR, Manohar, SG, Husain, M

“…<p><strong>Background:</strong> Autoimmune limbic encephalitis (ALE) is a neurological disease characterised by inflammation of the limbic regions of the brain, mediated by pathogenic autoantibodies. …”

An atomtronic experimental setup for engineering quantised circulations by Gan, Koon Siang

“…The dynamics of these simulated systems are useful for quantum metrology, magnetic sensing, rotational sensing and even to simulate black holes. …”
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A comprehensive review of dwell time optimization methods in computer-controlled optical surfacing by Wang, Tianyi, Ke, Xiaolong, Huang, Lei, Cui, Qingqing, Zhang, Zili, Wang, Chunjin, Kang, Hyukmo, Pullen, Weslin, Choi, Heejoo, Kim, Daewook, Negi, Vipender, Kemao, Qian, Zhu, Yi, Giorgio, Stefano, Boccabella, Philip, Bouet, Nathalie, Austin, Corey, Idir, Mourad

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Engineering quantum control with optical transitions induced by twisted light fields by Zanon-Willette, Thomas, Impens, François, Arimondo, Ennio, Wilkowski, David, Taichenachev, Aleksei V., Yudin, Valeriy I.

“…Engineering light-matter interaction by optical vortices merged with composite pulses will ultimately benefit experimental atomic and molecular platforms targeting an optimal coherent control of quantum states, reliant quantum simulation, novel approaches to atomic interferometry, and precision tests of fundamental theories in physics and high-accuracy optical metrology.…”
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Autoimmune encephalitis by Irani, SR

“…Forms of autoimmune encephalitis are more prevalent than infectious encephalitis and represent treatable neurologic syndromes for which early immunotherapies lead to the best outcomes.…”