A pilot study on peptidylarginine deiminases and protein deimination in animal cancers across vertebrate species by Inal, Jameel, Hristova, Mariya, Lange, Sigrun

“…Both PAD2 and PAD3 were the most predominantly expressed PADs across all of the cancers assessed, while PAD1, PAD4, and PAD6 were overall expressed at lower, albeit varying, levels. The findings from this pilot study provide novel insights into PAD-mediated roles in different cancers across a range of vertebrate species and may aid in the understanding of cancer heterogeneity and cancer evolution.…”
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Sustainable performance through digital supply chains in industry 4.0 era: amidst the pandemic experience by Joshi, Sudhanshu, Sharma, Manu

“…The study calls for firms to employ multiple DSCs once they have set clear strategic priorities. The overall findings of the work fill the literature gaps of studies in the digitalization of supply chains.…”
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Postural stability in cyclists by Preece, Mia, Grainger, Karl, Starrs, Paul

“…Conclusion: MTB balance was worse than RC balance, but both cycling groups were found to have better balance scores than the control. These findings have implications for public health, as cycling, an inexpensive and accessible activity already known to offer substantial health benefits, could additionally help maintain postural stability and potentially reduce risk of falls in later life.…”
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Can industry 5.0 technologies overcome supply chain disruptions? A perspective study on pandemics, war, and climate change issues by Agrawal, Shruti, Agrawal, Rohit, Kumar, Anil, Luthra, Sunil, Garza-Reyes, Jose Arturo

“…This study summarises 194 research articles from the period 2009 to 2022 to understand the present knowledge connected with this theme. The research findings show a significant gap related to the adoption of I5.0 technologies to prevent or overcome supply chain disruptions. 194 articles, including journal and review articles, were identified in the literature. …”
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How counselling psychologists address issues of race with clients from black Asian and minority ethnic backgrounds: a discourse analysis by Madre de Deus de Sousa, Filipe Alexandre, Banbury, Samantha, Phillips, Olaide, Lusher, Joanne

“…The first two discourses alluded to similar repertoires present in the discussions of white counselling psychologist participants, whereas the discourse challenging systemic racism was constructed by BAME counselling psychologists. Findings indicate that becoming attuned and open to discussing race-related difficulties supports favorable outcomes in practice when engaging with BAME individuals. …”
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The relationship between the moderate–heavy boundary and critical speed in running by Hunter, Ben, Meyler, Samuel, Maunder, Ed, Cox, Tobias H., Muniz-Pumares, Daniel

“…Conclusions: The study highlights some uncertainty in the fraction of T1 relative to CS, influenced by inconsistent approaches in determining both boundaries. However, our findings serve as a foundation for remote analysis and prescription of exercise intensity, although testing is recommended for more precise applications.…”
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Accelerating black objects and their holographic duals by Boido, A

“…</p> <p>We illustrate our findings with many examples throughout, including an explicit solution obtained in 5d STU gauged supergravity and uplifted on a five-sphere.…”

Agamben's understanding of time and its implications for Christology by Wright, O

“…But in the case of Agamben’s work, the discussion of temporality finds a new form of textual presentation: Agamben seeks to orchestrate other ‘texts’ (St Paul’s letters, Franciscan Rules of Life, poetry, art) to create an experience in his reader of his understanding of time. …”

Goblet cell differentiation in colorectal cancer by Abdullayeva, G

“…Therefore, investigating the regulatory mechanisms associated with goblet cell differentiation is important for a better understanding of CRC and finding new approaches to its prevention and treatment.…”

Precursors and correlates of transient and persistent longitudinal profiles of psychotic experiences from late childhood through early adulthood by Rammos, A, Sullivan, SA, Kounali, D, Jones, HJ, Hammerton, G, Hines, LA, Lewis, G, Jones, PB, Cannon, M, Thompson, A, Wolke, D, Heron, J, Zammit, S

“…</p> <br> <p><strong>Conclusions:</strong> These findings indicate that the same risk factors are associated with incidence as with persistence of psychotic experiences. …”

A comparative analysis of vitrification and two slow freezing methods for gonocyte-containing neonatal calf testicular tissue and subsequent in vitro culture by Tang, S, Jones, C, Davies, J, Lane, S, Coward, K

“…Collectively, these findings propose vitrification as a promising alternative cryopreservation method for immature testicular tissue (ITT) in clinical applications. …”

Pan-European atmospheric lead pollution, enhanced blood lead levels, and cognitive decline from Roman-era mining and smelting by McConnell, JR, Chellman, N, Plach, A, Wensman, SM, Plunkett, G, Stohl, A, Smith, N, Vinther, BM, Dahl-Jensen, D, Steffensen, JP, Fritzsche, D, Brugger, SO, McDonald, BT, Wilson, AI

“…Here we determined potential health effects of this air pollution using Arctic ice core measurements of Roman-era lead pollution, atmospheric modeling, and modern epidemiology-based relationships between air concentrations, blood lead levels, and cognitive decline. Findings suggest air lead concentrations exceeded 150 ng/m3 near metallurgical emission sources, with average enhancements of &gt;1.0 ng/m3 over Europe during the Pax Romana apogee of the Roman Empire. …”

Hormone replacement therapy and cancer survival: a longitudinal cohort study: protocol paper by Ranger, TA, Burchardt, J, Clift, AK, Mei, WX, Coupland, C, Tan, PS, Dixon, S, Cardwell, CR, Hippisley-Cox, J

“…We intend to the submit the findings for peer-reviewed publication in an academic journal and disseminate them to the public through Cancer Research UK.…”

Factors influencing macrophage phagocytosis and killing of Gram negative bacteria by Kurzyp, K

“…I showed that the effect of the GPR84 agonist 6-OAU was GPR84 specific in murine macrophages; in human macrophages, all three novel agonists tested were GPR84 specific.</p> <p>My findings provide novel tools and insights into factors involved in the interaction of <em>N. gonorrhoeae</em> and <em>E. coli</em> with macrophages, and suggest how macrophage receptors could be exploited to enhance bacterial killing for immune adjuvant therapy of infection.…”

Mobilising stone: investigating relations of materiality, movement and corporality in Holocene Saharan rock-art by Waldock, V

“…</p> <p>Other significant findings include detailed information on the role and identity of the image-maker, revisionist data on the amount of effort and skill expended in carving processes, and an examination of the ways in which rock-art was used to manifest social emotional concerns. …”

Symptom flares in women with chronic pelvic pain: questionnaire study within a cohort study (translational research in pelvic pain (TRiPP)) by Coxon, L, Lugt, C, Horne, AW, Evans, E, Abreu- Mendes, P, Arendt-Nielsen, L, Aziz, Q, Becker, CM, Birch, J, Charrua, A, Demetriou, L, Ferreira-Gomes, J, Hoffman, A, Hummelshoj, L, Krassowski, M, Lunde, CE, Meijlink, J, Missmer, SA, Perro, D, Zondervan, KT, Sieberg, CB, Cruz, F, Nagel, J, Vincent, K

“…Clinical practice should include an enquiry into flares with the aim of finding strategies to lessen their burden.</p>…”

Better floors, better health: a theory of change for an improved household flooring intervention in rural communities in Kwale and Bungoma counties, Kenya by Kepha, S, Legge, H, Halliday, KE, Ochwal, V, Elson, L, Mwongeli, J, Oswald, WE, Kakoi, B, Wambua, J, Mwandawiro, C, Fillinger, U, Pullan, R, Njomo, D

“…This paper presents the findings from a theory of change development process that was undertaken as part of the formative research phase of the SABABU project. …”

Legal politics in the Libyan constitution-making process by van Lier, F

“…Both scholars and practitioners assume that legal procedures and standards of constitution-making provide structures for resolving potentially violent political contest and debate, and thereby contribute to reconciliation and consensus finding. It is hoped that such processes will amplify commonality and strengthen democracy in a state. …”

Privacy: a political approach by Bogue, RC

“…It can thus be shown that a commitment to democracy entails a commitment to certain privacy rights—a finding that circumvents the difficulty in establishing a common basis for privacy protections by appealing to all citizens who live under democratic regimes. …”

Understanding the disease mechanisms of cerebellar ataxia through induced pluripotent stem cell models by Wong, M

“…Importantly, results obtained in SCA14 iPSCs faithfully recapitulated the pathological findings observed in the patient post-mortem cerebellum. …”