Elucidating the role of metabolic changes in modulating cell fate following treatment with anti-mitotic drugs by Wong, Alex Xing Fah

“…Anti-mitotic drugs are the most-commonly utilised class of chemotherapeutic agents that are administered as first-line therapy; however, their clinical success has been impeded by chemoresistance and disease relapse. …”
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Proteome mapping of Plasmodium: identification of the P. yoelii remodellome by Siau, Anthony, Huang, Ximei, Weng, Mei, Sze, Siu Kwan, Preiser, Peter R.

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M-OTDR sensing system based on 3D encoded microstructures by Sun, Qizhen, Ai, Fan, Liu, Deming, Cheng, Jianwei, Luo, Hongbo, Peng, Kuan, Luo, Yiyang, Yan, Zhijun, Shum, Perry Ping

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A Preliminary Study on the Extrusion Resolution of Pluronic F127 for Bioprinting Thermo-responsive Hydrogel Constructs by Suntornnond, Ratima, An, Jia, Chua, Chee Kai

“…The results show that the thinnest continuous line (highest resolution) of hydrogel could be obtained even when a larger nozzle is used. …”
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Experimental demonstration of Fabry-Perot open resonators in a surface-wave bandgap crystal by Gao, Zhen, Gao, Fei, Xu, Hongyi, Zhang, Youming, Zhang, Baile

“…This surface-wave FP open resonator is formed by introducing a finite line defect in the surface-wave bandgap crystal, whose resonance frequencies lie exactly within the forbidden bandgap of the surrounding crystal. …”
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Resistive switching memory phenomena in PEDOT PSS : coexistence of switchable diode effect and write once read many memory by Nguyen, Viet Cuong, Lee, Pooi See

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Eigen-analysis reveals components supporting super-resolution imaging of blinking fluorophores by Agarwal, Krishna, Prasad, Dilip Kumar

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Correlation between optical absorption redshift and carrier density in phase change materials by Ho, H. W., Song, W. D., Bai, K., Branicio, P. S., Tan, Teck L., Ji, R., Law, L. T., Ng, C. M., Lan, Wang.

“…We found that, with phase change from amorphous to crystalline, the observed redshift increases with Ge concentration along pseudo-line of compositions, which directly reflects the enhanced electron delocalization/resonant bonding and increased carrier concentrations in the respective crystal compounds. …”
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A new hybrid method for 3D object recovery from 2D drawings and its validation against the cubic corner method and the optimisation-based method by Lee, Yong Tsui, Fang, Fen

“…This paper uses a hybrid method to reconstruct 3D polyhedral objects from 2D line drawings by combining two known methods, the cubic corner method and the optimisation-based method, and presents comprehensive test results comparing the three methods. …”
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Hierarchical TiO2 nanoflakes and nanoparticles hybrid structure for improved photocatalytic activity by Tang, Yuxin, Wee, Peixin, Lai, Yuekun, Wang, Xiaoping, Gong, Dangguo, Kanhere, Pushkar D., Lim, Teik-Thye, Dong, Zhili, Chen, Zhong

“…The nanostructure of hierarchical microspheres undergoes three evolution steps, which includes the change from nanosheets into hybrid nanoflakes/nanoparticles and finally to nanoparticles as calcination temperature increases, in line with the predicable trend of increase in crystallinity and decrease in specific surface area. …”
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Relationship between irregularities of the nuclear envelope and mitochondria in HeLa cells observed with electron microscopy by Brito-Pacheco, Daniel, Karabağ, Cefa, Brito-Loeza, Carlos, Giannopoulos, Panos, Reyes-Aldasoro, Constantino Carlos

“…Whilst these results were obtained from a single cell line and a relatively small number of cells, they encourage further study as the methodology proposed can be easily applied to other cells and settings. …”
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Investigating the role of phosphatases in the regulation of mitosis by Leitch, I

“…</p> <p>This study also demonstrates the role of PLK1 activity in the initial recruitment of the phosphatase PP2A-B56 to kinetochores using a fluorescently labelled B56 CRISPR cell line. Additional tools for investigating the role of PLK1 in the formation of stable kinetochore-microtubule attachments are also generated and preliminary experiments carried out.…”

Chloroquine has shown high therapeutic efficacy against uncomplicated Plasmodium vivax malaria in southern Ethiopia: seven decades after its introduction by Mare, AK, Mohammed, H, Sime, H, Hailgiorgis, H, Gubae, K, Gidey, B, Haile, M, Assefa, G, Bekele, W, Auburn, S, Price, R, Parr, JB, Juliano, JJ, Tasew, G, Abay, SM, Assefa, A

“…<p><strong>Background: </strong><em>Plasmodium vivax</em> malaria is a leading cause of morbidity in Ethiopia. The first-line treatment for <em>P. vivax</em> is chloroquine (CQ) and primaquine (PQ), but there have been local reports of CQ resistance. …”

The mechanisms of sleep restriction therapy for insomnia disorder by Maurer, LF

“…While pharmacological treatment is available, the current recommended first-line intervention is a multi-component psychological therapy called cognitive behavioural therapy for insomnia (CBT-I). …”

Role of Tau and NRF2 in oxidative stress responses by Ameyaw, B

“…In the neuroblastoma cell line SH-SY5Y, which expresses high levels of Tau, Tau KO led to increased oxidative stress, reversible by re-expressing Tau, but not fully rescued by NRF2 upregulation or microtubule stabilisation.…”

Autoimmune encephalitis by Irani, SR

“…Observational studies provide the mainstay of evidence guiding first- and second-line immunotherapy administration in autoimmune encephalitis and, whereas these typically result in some clinical improvements, almost all patients have residual neuropsychiatric deficits, and many experience clinical relapses. …”

Literary metatranslation: understanding the multiple in post-communist Poland by Szymanska, K

“…In discussing the ethical ideas underpinning these works, I demonstrate how literary metatranslations and their gesture of acknowledging more than one view and line of thinking could also undermine totalised discourses and put forward a more democratic agenda.…”

Structural basis of haptoglobin-haemoglobin scavenging by CD163 by Zhou, X

“…Haptoglobin (Hp) acts as the first line of defence by scavenging Hb in the serum. Humans produce three major Hp phenotypes, the dimeric Hp 1-1 as well as the multimeric Hp 2-1 and 2-2. …”

PRMT5 controls the innate immune response by Zhang, C

“…We hypothesised that PRMT5 inhibition could increase retained introns (RIs) in the colorectal cancer cell line HCT116, leading to the production of immunogenic double-stranded RNAs (dsRNAs). …”

The bHLH transcription factor OsPRI1 activates the Setaria viridis PEPC1 promoter in rice by Carvalho, P, Gomes, C, Gonçalves, I, Lourenço, TF, Vlad, D, Langdale, JA, Saibo, NJM

“…The role of OsPRI1 <i>in planta</i> was characterized using a rice line harbouring <i>SvPEPC1_pro::GUS</i>.…”