High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer by Palafox, Marta, Monserrat, Laia, Bellet, Meritxell, Villacampa, Guillermo, Gonzalez-Perez, Abel, Oliveira, Mafalda, Brasó-Maristany, Fara, Ibrahimi, Nusaibah, Kannan, Srinivasaraghavan, Mina, Leonardo, Herrera-Abreu, Maria Teresa, Òdena, Andreu, Sánchez-Guixé, Mònica, Capelán, Marta, Azaro, Analía, Bruna, Alejandra, Rodríguez, Olga, Guzmán, Marta, Grueso, Judit, Viaplana, Cristina, Hernández, Javier, Su, Faye, Lin, Kui, Clarke, Robert B., Caldas, Carlos, Arribas, Joaquín, Michiels, Stefan, García-Sanz, Alicia, Turner, Nicholas C., Prat, Aleix, Nuciforo, Paolo, Dienstmann, Rodrigo, Verma, Chandra Shekhar, Lopez-Bigas, Nuria, Scaltriti, Maurizio, Arnedos, Monica, Saura, Cristina, Serra, Violeta

“…Here, we show that p16 overexpression is associated with reduced antitumor activity of CDK4/6 inhibitors in patient-derived xenografts (n = 37) and estrogen receptor-positive breast cancer cell lines, as well as reduced response of early and advanced breast cancer patients to CDK4/6 inhibitors (n = 89). …”
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Observation of flat bands and Dirac cones in a pyrochlore lattice superconductor by Huang, Jianwei, Setty, Chandan, Deng, Liangzi, You, Jing-Yang, Liu, Hongxiong, Shao, Sen, Oh, Ji Seop, Guo, Yucheng, Zhang, Yichen, Yue, Ziqin, Yin, Jia-Xin, Hashimoto, Makoto, Lu, Donghui, Gorovikov, Sergey, Dai, Pengcheng, Denlinger, Jonathan D., Allen, J. W., Hasan, M. Zahid, Feng, Yuan-Ping, Birgeneau, Robert J., Shi, Youguo, Chu, Ching-Wu, Chang, Guoqing, Si, Qimiao, Yi, Ming

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Novel method of probe design for characterising unclassified microbial taxa in wastewater by Tan, Shi Ming

“…Shimingles; distinct clades were in line with two draft genomes recovered through genomic binning. …”
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InAlN/GaN high electron mobility transistors on Si for RF applications by Xing, Weichuan

“…Also, device geometries including gate length, line-to-space ratio of the nanostripchannel and gate-to-source distance have been studied. …”
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Analysis and design of curved steel beam member in elevation using Eurocode 3 by Yandarmadi, Kelvin

“…But on the other hand, it has the smallest axial force value. The three-hinged circular arch generally has higher axial force and shear force value than the two-hinged arch. …”
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Multi-site benchmark classification of major depressive disorder using machine learning on cortical and subcortical measures by Belov, Vladimir, Erwin-Grabner, Tracy, Aghajani, Moji, Aleman, Andre, Amod, Alyssa R., Basgoze, Zeynep, Benedetti, Francesco, Besteher, Bianca, Bülow, Robin, Ching, Christopher R. K., Connolly, Colm G., Cullen, Kathryn, Davey, Christopher G., Dima, Danai, Dols, Annemiek, Evans, Jennifer W., Fu, Cynthia H. Y., Gonul, Ali Saffet, Gotlib, Ian H., Grabe, Hans J., Groenewold, Nynke, Hamilton, J. Paul, Harrison, Ben J., Ho, Tiffany C., Mwangi, Benson, Jaworska, Natalia, Jahanshad, Neda, Klimes-Dougan, Bonnie, Koopowitz, Sheri-Michelle, Lancaster, Thomas, Li, Meng, Linden, David E. J., MacMaster, Frank P., Mehler, David M. A., Melloni, Elisa, Mueller, Bryon A., Ojha, Amar, Oudega, Mardien L., Penninx, Brenda W. J. H., Poletti, Sara, Pomarol-Clotet, Edith, Portella, Maria J., Pozzi, Elena, Reneman, Liesbeth, Sacchet, Matthew D., Sämann, Philipp G., Schrantee, Anouk, Sim, Kang, Soares, Jair C., Stein, Dan J., Thomopoulos, Sophia I., Uyar-Demir, Aslihan, van der Wee, Nic J. A., van der Werff, Steven J. A., Völzke, Henry, Whittle, Sarah, Wittfeld, Katharina, Wright, Margaret J., Wu, Mon-Ju, Yang, Tony T., Zarate, Carlos, Veltman, Dick J., Schmaal, Lianne, Thompson, Paul M., Goya-Maldonado, Roberto

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Frequency equations of nonlocal elastic micro/nanobeams with the consideration of the surface effects by Zhao, Haisheng, Zhang, Yao, Lie, Seng Tjhen

“…Three types of boundary conditions, i.e., hinged-hinged, clamped-clamped, and clamped-hinged ends, are examined. …”
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Innovative UWB phase shifters using groove gap-waveguide technology inspired by metasurfaces for beamforming networks operating at 100 GHz by Alibakhshikenari, Mohammad, Zidour, Ali, Virdee, Bal Singh, Kouhalvandi, Lida, Shahid, Saleem, See, Chan Hwang, Limiti, Ernesto

“…The metasurface features a "bed-of-nails" structure, where metal pins are connected to a bottom layer and spaced <λ/4 from a top plate. …”
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Hydrophosphination as a valuable tool to chiral diphosphines and their derivatives by Teo, Ronald Hong Xiang

“…Next, the synthesis of C-chiral diphosphines from naturally occurring curcumin and derivatives was attempted and the cytotoxicity of the diphosphine metal complexes was evaluated and compared against cisplatin and curcumin in the MKN74 and MCF7 cancer cell-lines. Lastly, the challenges associated with the generation of chiral phosphine-phosphino-chalcogenide and their complexes were discussed in detail and an example of the catalytic property of the phosphine-phosphino-chalcogenide metal complexes was illustrated.…”
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Creative producing for milk: navigating the balance of artistry and feasibility by Hing, Su Yi

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Home automation system using Raspberry Pi by Wang, Yangyang

“…Through out this project, student will gain knowledge in areas such as understand Raspberry Pi’s background; Raspberry Pi’s command lines; how to control GPIO pins; how to use PuTTY to remotely access the Raspberry Pi; understand web server Apache and PHP; understand WinSCP and how to transfer files with it; have the knowledge of web interface design, understand HTML5, CSS, PHP and JavaScript and be able to do electrical wiring and mechanical modification for the equipment required in the project.…”
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US and East Asia Summit : international security begins at home by Long, Joey S. R., Khan, Amos

“…The political demise of prime ministers Yukio Hatoyama and Kevin Rudd is a reminder that national leaders’ capacity to contribute to international security hinges on the stability of their domestic authority. …”
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Development of high frequency power supply for radio frequency ablation machine / by Lau Ngie Hing, 1990-, author 644938, Zolkafle Buntat, supervisor 486106, Fakulti Kejuruteraan Elektrik 540663

Design and analysis of a flexure bearing by Balakrishnan Sathish Kumar

“…Hence, a more compliant bearing using flexures in a cross form can be chosen for hinges requiring large deflections with is robust.…”
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Development of high frequency power supply for radio frequency ablation machine [electronic resource] / by Lau Ngie Hing, 1990-, author 644938, Zolkafle Buntat, supervisor 486106, Fakulti Kejuruteraan Elektrik 540663

Process re-engineering of airfreight export operations by Chow, Yew Sun.

“…This fact is predicated on Singapore's position as a major manufacturing base for high technology products and the concomitant trends that is the quintessential of such industries: JIT; small shipments; more frequent shipments; CRM which hinges on quicker response to customer orders.…”
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Relationship between working memory and mental addition of upper primary pupils by Lok, Mee Hing.

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Design Si photonic devices for data centre and telecommunication applications by Vendy, Vicki

“…Micro-ring resonator could be used for biochemical sensing applications and many others [1], in this work simulations using LUMERICAL mode will be done by student to gain a better understanding of the design and optimization of micro-ring sensors. …”
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NAPE-PLD, a viable antimalarial drug target? by Ng, Brandon Jian Le

“…Due to added resistance, ring-stage parasite are becoming harder to eliminate, therefore exacerbating the need for novel ring-stage target for antimalarial treatments.In this study, we investigated N-acylphosphatidylethanolamine Phospholipase D (NAPEPLD) as a potential ring-stage target for treatment. …”
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Design of optical building blocks for photonic integration by Chin, Mee Koy.

“…The existence of defect mode in linear and lossless ring resonator arrays is also demonstrated. The defect can be introduced by removing one ring or by making one ring bigger or smaller. …”
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