Determinants of underdiagnosis of COPD in national and international surveys by Lamprecht, B, Soriano, JB, Studnicka, M, Kaiser, B, Vanfleteren, LE, Gnatiuc, L, Burney, P, Miravitlles, M, García-Rio, F, Akbari, K, Ancochea, J, Menezes, AM, Perez-Padilla, R, Montes de Oca, M, Torres-Duque, CA, Caballero, A, González-García, M, Buist, S

“…</p> <p><strong>Methods:</strong> We analyzed representative samples of adults aged ≥ 40 years randomly selected from well-defined administrative areas worldwide (44 sites from 27 countries). Postbronchodilator FEV1/FVC &lt; lower limit of normal (LLN) was used to define chronic airflow limitation consistent with COPD. …”

Advancing artemisinin resistance monitoring using a high sensitivity ddPCR assay for Pfkelch13 mutation detection in Asia by Srisutham, S, Saejeng, A, Khantikul, N, Sugaram, R, Sangsri, R, Dondorp, AM, Day, NPJ, Imwong, M

“…The R539T, R561H, and C580Y mutations were detected in clinical samples collected from several study sites in Thailand. Notably, the R561H mutation was detected in 100% of the P. falciparum isolates from Mae Hong Son, Thailand in 2023, underscoring the assay’s utility in identifying critical mutations associated with drug resistance. …”

Assessing the odd secondary structural properties of nuclear small subunit ribosomal RNA sequences (18S) of the twisted-wing parasites (Insecta: Strepsiptera) by Gillespie, J, McKenna, C, Yoder, M, Gutell, R, Johnston, J, Kathirithamby, J, Cognato, A

“…Analysis of our structural alignment revealed four unusual insertions in the core rRNA structure that are unique to animal 18S rRNA and in general agreement with previously proposed insertion sites for strepsipterans. One curious result is the presence of a large insertion within a hairpin loop of a highly conserved pseudoknot helix in variable region 4. …”

Mobilizing bodies: unsettling sustainable mobility through cycling in Los Angeles by Davidson, AC

“…</p> <p>In this dissertation, I work through a methodology of 'riding theory' by bringing together (material) feminist, queer and critical race theories with multi-sited ethnographic fieldwork on cycling practices, focusing mainly on Los Angeles, California. …”

Testing the effect of ecolabels on the environmental impact of food purchases in worksite cafeterias: a randomised controlled trial by Luick, M, Stewart, C, Clark, M, Bateman, P, Biggs, E, Cook, B, Little, M, Wren, GM, Jebb, SA, Pechey, R

“…Results: There was no significant effect of the intervention on the environmental impact scores of meals sold (mean difference between control and intervention sites: -1.4%, 95%CI: -33.6%, + 30.8%). There was no evidence of an effect in mean weekly environmental impact score (-5.4%, 95%CI: -12.6%, + 2.5%), nor in any of the four individual environmental indicators (greenhouse gas emissions: -3.6%, 95%CI: -30.7%, 34.3%; biodiversity loss: 2.0%, 95%CI: -25.8%, 40.2%; eutrophication: -2.4%, 95%CI: -29.3%, 34.7%; water scarcity: -0.4%, 95%CI: -28.7%, 39.1%). …”

Elucidating the mechanism of mRNA transport using novel imaging technologies by Stoychev, D

“…To support their function and to maintain homeostasis, the cells need to supply signals and resources like proteins to such remote sites away from the nucleus. This is particularly important for dynamic processes such as cytoskeletal rearrangement, membrane trafficking, and synaptic plasticity. …”

A low-cost, open-source cylindrical Couette rheometer by Erni, Makita, Hart, A. John, Trumper, David, Owens, Crystal E.

“…As a result, rheometers are typically large, expensive, and require additional infrastructure (e.g., gas lines), rendering them inaccessible for regular use by many individuals, small organizations, and educators. …”
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Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans by Xu, Luang, Liu, Xinyu, Sheng, Na, Oo, Kyaw Soe, Liang, Junxin, Chionh, Yok Hian, Xu, Juan, Ye, Fuzhou, Gao, Yong-Gui, Dedon, Peter C., Fu, Xin-Yuan

“…METTL8, however, modified only mRNA, as determined by biochemical and genetic analyses in Mettl8 null-mutant mice and two human METTL8 mutant cell lines. Our findings provide the first evidence of the existence of m3C modification in mRNA, and the discovery of METTL8 as an mRNA m3C writer enzyme opens the door to future studies of other m3C epitranscriptomic reader and eraser functions.…”
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Holocene rate of slip and tentative recurrence interval for large earthquakes on the San Andreas fault, Cajon Pass, southern California by Sieh, Kerry, Weldon, Ray J.

“….; it has provided tentative evidence for 6 earthquakes in about the past 1,000 yr. Both lines of evidence suggest an average recurrence interval for large earthquakes of ∼1½ to 2 centuries. …”
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Who learns when workers are trained? a case of safety training of maintenance contractors’ workers for a major petrochemical plant shutdown by A., Fakhru'l-Razi, S.E., Iyuke, M.B., Hassan, M.S., Aini

“…The curves obtained are typical for the whole exercise, which gave perfect straight lines for Introduction to Safety, Hydrogen Sulphide, Confine Space and Permit to Work, respectively. …”
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A novel human stem cell platform for probing adrenoceptor signaling in iPSC derived cardiomyocytes including those with an adult atrial phenotype by Ahmad, F

“…</p> <p>Drug targeting of atrial-specific ion channels has been difficult because of lack of availability of appropriate cardiac cells, and preclinical testing studies have been carried out in non-cardiac cell lines, heterogeneous cardiac populations or animal models that have been unable to accurately represent human cardiomyocyte physiology. …”

An aerodynamic investigation of a high-pressure turbine using rotor casing static pressure measurements at engine representative conditions with different tip designs, tip gaps and... by Singh, D, Beard, PF, Cardwell, D, Staelens, V, Bahulekar, P, Stokes, M, Bather, S, Chana, KS

“…Steady and unsteady casing static pressure measurements were acquired, using pneumatic lines and high-frequency response (∼100 kHz) Kulite pressure transducers respectively. …”

Inflammation and colorectal cancer: elucidation of the cellular and molecular mechanisms by which interleukin 22 contributes to the development and progression of colorectal cancer by McCuaig, S

“…Using a panel of CRC cell lines and primary human organoids, we confirmed that this prognostic association is due to a functional interaction between IL-22 and mutant KRAS by observing that IL-22 enhances chemoresistance, 3-dimensional clonogenicity, and proliferation specifically in CRC cells with both high IL-22 receptor levels and <em>KRAS</em> mutations. …”

Citizenship and the politics of poverty definition during the segregation, apartheid and democratic eras in South Africa: 1910-2010 by Magasela, W

“…The Household Subsistence Level (HSL) and the Minimum Living Level (MLL) were derivatives of the PDL (the HSL was exactly the PDL, the MLL was lower in value) and were conceptually similar were used as poverty definitions and poverty lines to fix the wages of black workers, thus showing the link between the denial of citizenship and the politics of poverty definition.…”

Assessing the kinetics of oxygen-unloading from red cells using FlowScore, a flow-cytometric proxy of the functional quality of blood by Rabcuka, J, Smethurst, P, Dammert, K, Saker, J, Aran, G, Walsh, G, Tan, J, Codinach, M, McTaggart, K, Marks, D, Bakker, S, McMahon, A, Di Angelantonio, E, Roberts, D, Blonski, S, Korczyk, P, Shirakami, A, Cardigan, R, Swietach, P

“…Applying FlowScore to data from the COMPARE study revealed a positive association with the time-delay from sample collection to measurement, which was verified experimentally. The LifeLines dataset revealed age, sex, and smoking among factors affecting FlowScore. …”

Dress, Feminism, and British New Woman Novels by Allen-Johnstone, C

“…For example, Grand elevated cross-class feminism, but she belittled middle-class women's taste, side-lined poor women’s most pressing sartorial concerns, and dressed to impress. …”

Toward multivariate fragility functions for seismic damage and loss estimation of high-rise buildings by Kourehpaz, Pouria, Hutt, Carlos Molina, Lallemant, David

“…The proposed functions are used to evaluate the performance of a portfolio of modern high-rise reinforced concrete shear wall buildings at four sites across the Seattle, Washington metropolitan area under a potential magnitude-9 Cascadia subduction zone earthquake scenario. …”
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The biggest challenges resulting from the COVID-19 pandemic on gender-related work from home in biomedical fields—world-wide qualitative survey analysis by Bezak, Eva, Carson-Chahhoud, Kristin V., Marcu, Loredana G., Stoeva, Magdalena, Lhotska, Lenka, Barabino, Gilda A., Ibrahim, Fatimah, Kaldoudi, Eleni, Lim, Sierin, Da Silva, Ana Maria Marques, Tan, Peck Ha, Tsapaki, Virginia, Frize, Monique

“…Participants reported increased domestic duties, blurred lines between home and work, and long workdays. Finding adequate workspace was a problem, and adaptations were necessary, especially when adults shared the same setting for working and childcare. …”
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Exploring the trait plasticity of ipa1-2d and qpl6 under different nitrogen treatments and heading periods by Zhuang, Wenshu, Jin, Guangyang, Zou, Yiting, Bian, Zhong, Xie, Dong, Zhang, Shuwei, Yeilaghi, Hadi, Yu, Liangliang, Wong, Muiyun, Fan, Xiaolei, Zhao, Dongsheng, Liu, Qiaoquan, Zhang, Lin

“…QTL analysis could elaborate on the environmental impact on trait plasticity using nearly isogenic lines (NILs) of different QTLs. Two QTLs, ipa1-2D and qPL6 are identified to have pleio-tropic contributions to panicle size and plant architecture, but their responses to different growth conditions are still unclear. …”
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Analysing social presence in Whatsapp application using LIWC analysis by Siti Norzaimalina, Abd Majid, Abdul Rahim, Salam

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