Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial by Silk, SE, Kalinga, WF, Salkeld, J, Mtaka, IM, Ahmed, S, Milando, F, Diouf, A, Bundi, CK, Balige, N, Hassan, O, Mkindi, CG, Rwezaula, S, Athumani, T, Mswata, S, Lilolime, NS, Simon, B, Msami, H, Mohamed, M, David, DM, Mohammed, L, Nyaulingo, G, Mwalimu, B, Juma, O, Mwamlima, TG, Sasamalo, IA, Mkumbange, RP, Kamage, JJ, Barrett, JR, King, LDW, Hou, MM, Pulido, D, Carnrot, C, Lawrie, AM, Cowan, RE, Nugent, FL, Roberts, R, Cho, J-S, Long, CA, Nielsen, CM, Miura, K, Draper, SJ, Olotu, AI, Minassian, AM

“…<p><strong>Background:</strong> A blood-stage Plasmodium falciparum malaria vaccine would provide a second line of defence to complement partially effective or waning immunity conferred by the approved pre-erythrocytic vaccines. …”

High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer by Palafox, Marta, Monserrat, Laia, Bellet, Meritxell, Villacampa, Guillermo, Gonzalez-Perez, Abel, Oliveira, Mafalda, Brasó-Maristany, Fara, Ibrahimi, Nusaibah, Kannan, Srinivasaraghavan, Mina, Leonardo, Herrera-Abreu, Maria Teresa, Òdena, Andreu, Sánchez-Guixé, Mònica, Capelán, Marta, Azaro, Analía, Bruna, Alejandra, Rodríguez, Olga, Guzmán, Marta, Grueso, Judit, Viaplana, Cristina, Hernández, Javier, Su, Faye, Lin, Kui, Clarke, Robert B., Caldas, Carlos, Arribas, Joaquín, Michiels, Stefan, García-Sanz, Alicia, Turner, Nicholas C., Prat, Aleix, Nuciforo, Paolo, Dienstmann, Rodrigo, Verma, Chandra Shekhar, Lopez-Bigas, Nuria, Scaltriti, Maurizio, Arnedos, Monica, Saura, Cristina, Serra, Violeta

“…Here, we show that p16 overexpression is associated with reduced antitumor activity of CDK4/6 inhibitors in patient-derived xenografts (n = 37) and estrogen receptor-positive breast cancer cell lines, as well as reduced response of early and advanced breast cancer patients to CDK4/6 inhibitors (n = 89). …”
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InAlN/GaN high electron mobility transistors on Si for RF applications by Xing, Weichuan

“…Also, device geometries including gate length, line-to-space ratio of the nanostripchannel and gate-to-source distance have been studied. …”
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Multi-site benchmark classification of major depressive disorder using machine learning on cortical and subcortical measures by Belov, Vladimir, Erwin-Grabner, Tracy, Aghajani, Moji, Aleman, Andre, Amod, Alyssa R., Basgoze, Zeynep, Benedetti, Francesco, Besteher, Bianca, Bülow, Robin, Ching, Christopher R. K., Connolly, Colm G., Cullen, Kathryn, Davey, Christopher G., Dima, Danai, Dols, Annemiek, Evans, Jennifer W., Fu, Cynthia H. Y., Gonul, Ali Saffet, Gotlib, Ian H., Grabe, Hans J., Groenewold, Nynke, Hamilton, J. Paul, Harrison, Ben J., Ho, Tiffany C., Mwangi, Benson, Jaworska, Natalia, Jahanshad, Neda, Klimes-Dougan, Bonnie, Koopowitz, Sheri-Michelle, Lancaster, Thomas, Li, Meng, Linden, David E. J., MacMaster, Frank P., Mehler, David M. A., Melloni, Elisa, Mueller, Bryon A., Ojha, Amar, Oudega, Mardien L., Penninx, Brenda W. J. H., Poletti, Sara, Pomarol-Clotet, Edith, Portella, Maria J., Pozzi, Elena, Reneman, Liesbeth, Sacchet, Matthew D., Sämann, Philipp G., Schrantee, Anouk, Sim, Kang, Soares, Jair C., Stein, Dan J., Thomopoulos, Sophia I., Uyar-Demir, Aslihan, van der Wee, Nic J. A., van der Werff, Steven J. A., Völzke, Henry, Whittle, Sarah, Wittfeld, Katharina, Wright, Margaret J., Wu, Mon-Ju, Yang, Tony T., Zarate, Carlos, Veltman, Dick J., Schmaal, Lianne, Thompson, Paul M., Goya-Maldonado, Roberto

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Immobilization of cyclodextrin glucanotransferase on electrospun polyvinyl alcohol nanofibers by Saallah, Suryani

“…In this study, cyclodextrin glucanotransferase (CGTase) enzyme was successfully immobilised on PVA nanofibers via post-spinning and simultaneous electrospraying and electrospinning. …”
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Search for continuous gravitational wave emission from the Milky Way center in O3 LIGO-Virgo data by Sudhir, Vivishek

“…We present a directed search for continuous gravitational wave (CW) signals emitted by spinning neutron stars located in the inner parsecs of the Galactic Center (GC). …”
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Surface bio-magnetism and its biophysical effects on bacterial cells by Chua, Loh You

“…This is achieved by using the properties of anisotropy surface energy and the phemomena of ordered electron spins to either channel the energy away or towards the open surfaces, which affects the biophysical interactions with the adhering bacteria.…”
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First cycle voltage hysteresis in Li-rich 3d cathodes associated with molecular O2 trapped in the bulk by House, RA, Rees, G, Perez-Osorio, M, Marie, J-J, Boivin, E, Robertson, A, Nag, A, Garcia-Fernandez, M, Zhou, K-J, Bruce, P

“…Resonant inelastic X-ray scattering and 17O magic angle spinning NMR spectroscopy show that molecular O2, rather than O22−, forms within the particles on the oxidation of O2− at 4.6 V versus Li+/Li on charge. …”

Goblet cell differentiation in colorectal cancer by Abdullayeva, G

“…These groups included high, medium, and low MUC2/TFF3-expressing cell lines, cell lines with no/very low MUC2 but high TFF3 expression, and cell lines completely lacking these proteins. …”

Domain wall dynamics in engineered multilayer magnetic nanostructures by Lin, Eddy Junxiang

“…This is attributed to the spins of the domain wall in Co60Fe20B20 aligning along the magnetic moment of the permalloy strip above it. …”
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The theory of complex network sensing. by Wang, Yidan.

“…The objective of this project is to explore this interaction between internal dynamics and extrinsic information by simulating Ising spins on a scale-free network. As a first step to understand how complex networks sense and react to environmental signals, we studied how to achieve a global change of the system through the control of local nodes.…”
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Subprime crisis : the impact of different types of debt on corporate performance. by Lim, Chee Hau., Neo, Wei Ling., Lim, Brandon Weilong.

“…For pre-crisis to crisis period, result indicates that firms possessing pre-existing Undrawn Credit Lines during the pre-crisis period would not perform significantly better than firms which did not have access to Undrawn Credit Lines. …”
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Improving gene therapy by Wang, Eliza Lisha

“…Existing PT67 and Amphotropic-Phoenix retroviral packaging cell lines can be made more efficient to produce higher retroviral titers, giving rise to more efficient gene transfer. …”
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Automatic vanishing points detection for single view reconstruction by Potcharaphol, Chat Anan

“…The algorithm is found to be fast and effective for an image with clear feature lines but struggles with an image with few feature lines. …”
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Perceptual watermarking and data concealment in audio signals by Tio, Cedric Meng Meng.

“…This project aims to hide data in audio streams by direct substitution of the FFT spectral lines with the hidden data. The spectral lines to be replaced are carefully chosen with the help of a psychoacoustic model. …”
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POPX2 and its role in breast cancer. by Susila, Agatha.

“…We found that POPX2 is highly expressed in cancer cell lines compared to non-cancer cell lines.…”
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Fabrication of hollow fiber membranes using amphiphilic block copolymers as pore-forming additives by Loh, Chun Heng

“…Therefore, a second additive, which is either LiCl or water, has been added together with Pluronic in the spinning dope to examine the synergetic effects of mixed additives on macrovoid formation. …”
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Information pollution and the war in Gaza: implications for Singapore by Wong, Yasmine, Haciyakupoglu, Gulizar

“…Besides demonstrating various disinformation types and tactics, there is also the increased resonance of certain disinformation narratives as they overlap and impact on societal sensitivities and identity-based fault lines. These are challenges for Singapore, as societal fault lines present vulnerabilities for disinformation penetration, ultimately affecting social cohesion.…”
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Characterization of artemisinin resistance in plasmodium falciparum by Rocamora, Frances Maureen C.

“…Long term in vitro selection produced two parasite lines that displayed profound stage-specific resistance to artemisinin and its relative compounds. …”
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Gender equality, growth, and how a technological trap destroyed female work by Humphries, J, Schneider, B

“…We then explain how a crucial example of technological unemployment for women&#x2014;the destruction of hand spinning during the British Industrial Revolution&#x2014;contributed to the emergence of the male breadwinner family. …”