Systems medicine disease : disease classification and scalability beyond networks and boundary conditions by Berlin, Richard, Gruen, Russell, Best, James

“…When Disease is viewed beyond the thresholds of lines and threshold boundaries, disease definition is not only the result of reductionist, mechanistic categories which reluctantly face re-composition. …”
Get full text
Get full text

Entangled exclusions: borders, frontiers and urban geopolitics from northeast India by Das, P, Mittal, G, Sarma, J

“…These have, in turn, led to further displacement, enclavization, and ghettoization of minority communities who are deemed ‘non-native’ along ethnocentric lines. Taking two cases from Shillong and Guwahati, we introduce the concept of entangled exclusions to analyse the layered, intertwined, multi-scalar nature of divides within these frontier cities. …”

On shear adhesion of adhesive fibrils by Linghu, Changhong, Du, Zihao, Sun, Yi, Chen, Weiqiu, Hsia, K. Jimmy

“…These biological and bioinspired adhesive fibrils exhibit a wide range of aspect ratios spanning four orders of magnitude. Accurate prediction of their adhesion performance is crucial for their practical applications. …”
Get full text

Finite element analysis of a free-standing concrete sea-wall as alternative to traditional land reclamation by Harris, Raymond

“…Furthermore, a 3D caisson seawall model is used in the analysis so that the stiffness of the cellulated structure can be properly accounted for. The caisson seawall spans 40 m long to 28 m wide. It is connected on its longer side continuously so that it forms a wall barrier in which 20 m of seawater level will be drained from the usable side. …”
Get full text

Toward a neuroscientific understanding of play: a dimensional coding framework for analyzing infant–adult play patterns by Neale, Dave, Clackson, Kaili, Georgieva, Stanimira, Dedetas, Hatice, Scarpate, Melissa, Wass, Sam, Leong, Victoria

“…However, there is currently no integrated framework for conducting a multimodal analysis of play that spans brain, cognition and behavior. The proposed coding framework uses grounded and observable behaviors along three dimensions (sensorimotor, cognitive and socio-emotional), to compute inferences about playful behavior in a social context, and related social interactional states. …”
Get full text
Get full text

Imagined futures and relational agency in nurses' writing transitions: a qualitative study across two writing group interventions in a higher education setting by Waite, M

“…</p> <p>I collected data through participant observation, samples of writing-in-development, and individual narratives spanning up to three years. I analysed the data through a conceptual framework that draws theoretically from a sociocultural understanding of developmental transitions and a cultural-historical perspective on relational agency.…”

3D spheroid-microvasculature-on-a-chip for tumor-endothelium mechanobiology interplay by Zhang, Yingqi, Jiang, Fengtao, Zhao, Charles Yunduo, Cho, Ann-Na, Fang, Guocheng, Cox, Charles D., Zreiqat, Hala, Lu, Zu Fu, Lu, Hongxu, Ju, Arnold Lining

Get full text

Automatic metric 3D surface mesh generation using subdivision surface geometrical model. Part 1 : construction of underlying geometrical model by Lee, Chi King

“…By using the subdivision surface concept, the new mesh generator can generate finite element meshes to model a wide range of surfaces which may contain sharp features such as cusp points and crease lines. When comparing with other traditional algorithms which use analytical surface patches as the underlying geometrical model, the new mesh generation scheme can be used in applications such as large deformation or crack analyses in which the domains to be gridded are not well defined or involve changing boundaries. …”
Get full text
Get full text

Critical role for cold shock protein YB-1 in cytokinesis by Mehta, Sunali, Algie, Michael, Al-Jabry, Tariq, McKinney, Cushla, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Ma, Weini, Zhang, Jessie, Bartolec, Tara K., Masamsetti, V. Pragathi, Parker, Kim, Henderson, Luke, Gould, Maree L., Bhatia, Puja, Harfoot, Rhodri, Chircop, Megan, Kleffmann, Torsten, Cohen, Scott B., Woolley, Adele G., Cesare, Anthony J., Braithwaite, Antony

“…Here, we found that YB-1 depletion in several cancer cell lines and in immortalized fibroblasts resulted in cytokinesis failure and consequent multinucleation. …”
Get full text

Study on supply chain challenges in container shipping : the port operator's perspectice by Muhammad Zulkarnain Mess.

“…Main challenges faced by port operators highlighted in the report include the ever increasing size of vessels, the chronic problem of port congestions and mergers and acquisitions of shipping lines. Some recommendations made for these problems are best practices adopted by ports world wide, while others such as ‘sharing concept’ are derived personally. …”
Get full text

Empirical investigation on container port competition and cooperation by Aw, Bing Zong

“…Through empirical investigation and interviews with terminal operators, shipping lines and shippers, this paper aims to investigate the competitive factors in the current economic climate and the effect of sister-port agreements between container ports. …”
Get full text

Crypto-linguistics in Singapore : deciphering the Singapore Stone by Chua, Sock Hui

“…The Singapore Stone was a sandstone with around 50 lines of inscription, but was blown up in 1843. A fragment of the original stone now lies in the National Museum of Singapore. …”
Get full text

Doxorubicin-loaded cell-derived nanovesicles: an alternative targeted approach for anti-tumor therapy by Goh, Wei Jiang, Lee, Choon Keong, Zou, Shui, Woon, Esther, Czarny, Bertrand, Pastorin, Giorgia

“…Here, we report a systematic approach pertaining to various loading methods of the chemotherapeutic drug doxorubicin into our CDNs and examine the differential cellular uptake of drug-loaded CDNs in cancerous (HeLa) and healthy (HEK293) cell lines. Lastly, we proved that the addition of doxorubicin-loaded CDNs to the HeLa and HEK293 co-cultures showed a clear discrimination toward cancer cells at the cellular level. …”
Get full text
Get full text

Strontium isoscape of sub-Saharan Africa allows tracing origins of victims of the transatlantic slave trade by Wang, X, Bocksberger, G, Arandjelovic, M, Agbor, A, Angedakin, S, Aubert, F, Ayimisin, EA, Bailey, E, Barubiyo, D, Bessone, M, Bobe, R, Bonnet, M, Boucher, R, Brazzola, G, Brewer, S, Lee, KC, Carvalho, S, Chancellor, R, Cipoletta, C, Cohen, H, Copeland, SR, Corogenes, K, Costa, AM, Coupland, C, Neil, E

“…We demonstrate the efficacy of this Sr isoscape, in combination with other lines of evidence, to trace the African roots of individuals from historic slavery contexts, particularly those with highly radiogenic 87Sr/86Sr ratios uncommon in the African Diaspora. …”

Bitcoins in the Malaysian Economy by Miraz, Mahadi Hasan, Mohd Sharif, Kamal Imran, Hassan, Mohamad Ghozali, Ismail, Mohd Azril, Ahmad Mahyadin@Mahidin, Fariza

“…This study focused on individual facts and details, such as articles, reviews, forums, Malaysians brochure, business lines, and research reports. The study relies on secondary data. …”
Get full text

Proton-assisted redox-based three-terminal memristor for synaptic device applications by Liu, Lingli, Dananjaya, Putu Andhita, Chee, Mun Yin, Lim, Gerard Joseph, Lee, Calvin Xiu Xian, Lew, Wen Siang

Get full text

Highly rechargeable aqueous Sn-metal-based hybrid-ion batteries by Xiao, Tao, Liu, Lingli, Liu, Huan, Li, Ting, Cai, Da-Qian, Lew, Wen Siang, Zhang, Yongqi, Bao, Haoming, Yang, Jin-Lin, Fan, Hong Jin

Get full text

Development of differential optical absorption spectroscopy (DOAS) system for hazardous methane gas detection in the near infrared region by Khandaker, Sayma, Hasan, Md Mahmudul, Nurulain Nadhirah, Shaipizaman, Mohd Amir Shahlan, Mohd Aspar, Hadi, Manap

“…An in-depth examination of the absorption lines was conducted to determine the optimal wavelength for measurement. …”
Get full text

Hackathons as Participatory Design: Iterating Feminist Utopias by Hope, Alexis, D'Ignazio, Catherine, Hoy, Josephine, Michelson, Rebecca, Roberts, Jennifer, Krontiris, Kate, Zuckerman, Ethan

“…Key to our re-imagining of conventional innovation structures is a focus on experience design, where joy and play serve as key strategies to help people and institutions build relationships across lines of difference. We conclude with a discussion of design principles applicable not only to designers of events, but to social movement researchers and HCI scholars trying to address oppression through the design of technologies and socio-technical systems.…”
Get full text

Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors by Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole

“…We validate this technology with the rapid generation of three BCR KI lines expressing native human precursors, instead of computationally inferred germline sequences, to HIV broadly neutralizing antibodies. …”
Get full text