Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background by Nayak, S, Peto, TJ, Kucharski, M, Tripura, R, Callery, JJ, Quang Huy, DT, Gendrot, M, Lek, D, Nghia, HDT, van der Pluijm, RW, Dong, N, Long, LT, Vongpromek, R, Rekol, H, Hoang Chau, N, Miotto, O, Mukaka, M, Dhorda, M, von Seidlein, L, Imwong, M, Roca, X, Day, NPJ, White, NJ, Dondorp, AM

“…During this response, PfRAD5 and PfWD11 upregulate their respective alternatively/aberrantly spliced isoforms, suggesting their contribution to the protective response to artemisinins. …”

Thermal-disrupting interface mitigates intercellular cohesion loss for accurate topical antibacterial therapy by Hu, Benhui, Berkey, Christopher, Feliciano, Timothy, Chen, Xiaohong, Li, Zhuyun, Chen, Chao, Amini, Shahrouz, Nai, Mui Hoon, Lei, Qun-Li, Ni, Ran, Wang, Juan, Leow, Wan Ru, Pan, Shaowu, Li, Yong-Qiang, Cai, Pingqiang, Miserez, Ali, Li, Shuzhou, Lim, Chwee Teck, Wu, Yun-Long, Odom, Teri W., Dauskardt, Reinhold H., Chen, Xiaodong

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Counterproductive effects of anti-CD38 and checkpoint inhibitor for the treatment of NK/T cell lymphoma by Lee, Wendy W. L., Lim, Jing Quan, Tang, Tiffany Pooi Ling, Tan, Daryl, Koh, Ser Mei, Puan, Kia Joo, Wang, Liang Wei, Lim, Jackwee, Tan, Kim Peng, Chng, Wee Joo, Lim, Soon Thye, Ong, Choon Kiat, Rotzschke, Olaf

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Detection and characterisation of a sixth Candida auris clade in Singapore: a genomic and phenotypic study by Suphavilai, Chayaporn, Ko, Karrie Kwan Ki, Lim, Kar Mun, Tan, Mei Gie, Boonsimma, Patipan, Chu, Joash Jun Keat, Goh, Sui Sin, Rajandran, Prevena, Lee, Lai Chee, Tan, Kwee Yuen, Bushra Binte Shaik Ismail, Aung, May Kyawt, Yang, Yong, Sim, Jean Xiang Ying, Venkatachalam, Indumathi, Cherng, Benjamin Pei Zhi, Spruijtenburg, Bram, Chan, Kian Sing, Oon, Lynette Lin Ean, Tan, Ai Ling, Tan, Yen Ee, Wijaya, Limin, Tan, Ban Hock, Ling, Moi Lin, Koh, Tse Hsien, Meis, Jacques F., Tsui, Clement Kin Ming, Nagarajan, Niranjan

“…We aimed to characterise three unusual C auris isolates detected in Singapore, and to determine whether they constitute a novel clade distinct from all previously known C auris clades (I–V). Methods: In this genotypic and phenotypic study, we characterised three C auris clinical isolates, which were cultured from epidemiologically unlinked inpatients at a large tertiary hospital in Singapore. …”
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Increasing nausea and vomiting of pregnancy is associated with sex-dependent differences in early childhood growth: the GUSTO mother-offspring cohort study by Ong, Judith, Sadananthan, Suresh Anand, Soh, Shu-E, Ng, Sharon, Yuan, Wen Lun, Aris, Izzuddin M., Tint, Mya Thway, Michael, Navin, Loy, See Ling, Tan, Kok Hian, Godfrey, Keith M., Shek, Lynette P., Yap, Fabian, Lee, Yung Seng, Chong, Yap Seng, Chan, Shiao-Yng

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Dynamic chloride ion adsorption on single iridium atom boosts seawater oxidation catalysis by Duan, Xinxuan, Sha, Qihao, Li, Pengsong, Li, Tianshui, Yang, Guotao, Liu, Wei, Yu, Ende, Zhou, Daojin, Fang, Jinjie, Chen, Wenxing, Chen, Yizhen, Zheng, Lirong, Liao, Jiangwen, Wang, Zeyu, Li, Yaping, Yang, Hongbin, Zhang, Guoxin, Zhuang, Zhongbin, Hung, Sung-Fu, Jing, Changfei, Luo, Jun, Bai, Lu, Dong, Juncai, Xiao, Hai, Liu, Wen, Kuang, Yun, Liu, Bin, Sun, Xiaoming

“…The Ir/CoFe-LDH exhibits a remarkable oxygen evolution reaction activity (202 mV overpotential and TOF = 7.46 O2 s-1) in 6 M NaOH+2.8 M NaCl, superior over Cl--free 6 M NaOH electrolyte (236 mV overpotential and TOF = 1.05 O2 s-1), with 100% catalytic selectivity and stability at high current densities (400-800 mA cm-2) for more than 1,000 h.…”
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Persistent symptoms and association with inflammatory cytokine signatures in recovered coronavirus disease 2019 patients by Ong, Sean Wei Xiang, Fong, Siew-Wai, Young, Barnaby Edward, Chan, Yi-Hao, Lee, Bernett, Siti Naqiah Amrun, Chee, Rhonda Sin-Ling, Yeo, Nicholas Kim-Wah, Tambyah, Paul, Pada, Surinder, Tan, Seow Yen, Ding, Ying, Renia, Laurent, Leo, Yee Sin, Ng, Lisa F. P., Lye, David C.

“…Background: The complications and sequelae of coronavirus disease 2019 (COVID-19) and their effect on long-term health are unclear, and the trajectory of associated immune dysregulation is poorly understood. …”
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Electrostatic microfiltration (EM) enriches and recovers viable microorganisms at low-abundance in large-volume samples and enhances downstream detection by Liu, Yaoping, Raymond, Joshua J, Wu, Xiaolin, Chua, Patrina Wei Lin, Ling, Sharon Yan Han, Chan, Chia Ching, Chan, Cheryl, Loh, Joanne Xin Yi, Song, Melody Xing Yen, Ong, Matilda Yu Yan, Ho, Peiying, Mcbee, Megan E, Springs, Stacy L, Yu, Hanry, Han, Jongyoon

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Longitudinal assessment of antibiotic resistance gene profiles in gut microbiomes of infants at risk of eczema by Loo, Evelyn Xiu Ling, Zain, Amanda, Yap, Gaik Chin, Purbojati, Rikky Wenang, Drautz-Moses, Daniela Isabel, Koh, Yanqing Michelle, Chong, Yap Seng, Tan, Kok Hian, Gluckman, Peter D., Yap, Fabian, Eriksson, Johan Gunnar, Tham, Elizabeth, Shek, Lynette Pei-Chi, Kjelleberg, Staffan, Schuster, Stephan Christoph, Banerjee, Ritu, Lee, Bee Wah

“…Beta-lactam resistant Escherichia coli and Klebsiella pneumoniae were detected in 4 (5.3%) and 32 (42.7%) of subjects respectively. …”
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Observation of flat bands and Dirac cones in a pyrochlore lattice superconductor by Huang, Jianwei, Setty, Chandan, Deng, Liangzi, You, Jing-Yang, Liu, Hongxiong, Shao, Sen, Oh, Ji Seop, Guo, Yucheng, Zhang, Yichen, Yue, Ziqin, Yin, Jia-Xin, Hashimoto, Makoto, Lu, Donghui, Gorovikov, Sergey, Dai, Pengcheng, Denlinger, Jonathan D., Allen, J. W., Hasan, M. Zahid, Feng, Yuan-Ping, Birgeneau, Robert J., Shi, Youguo, Chu, Ching-Wu, Chang, Guoqing, Si, Qimiao, Yi, Ming

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Management of adult sepsis in resource-limited settings: global expert consensus statements using a Delphi method by Thwaites, L, Nasa, P, Abbenbroek, B, Dat, VQ, Finfer, S, Kwizera, A, Ling, L, Lobo, SM, Sinto, R, Aditianingsih, D, Antonelli, M, Arabi, YM, Argent, A, Azevedo, L, Bennett, E, Chakrabarti, A, De Asis, K, De Waele, J, Divatia, JV, Estenssoro, E, Evans, L, Faiz, A, Hammond, NE, Hashmi, M

Charting the path forward in Southeast Asia: Learning from the COVID-19 vaccination challenges in six ASEAN countries by Fu, Jolene Yin Ling, Pukhari, Muhammad Harith, Cruz, Kristine Alvarado-Dela, Soebandrio, Amin, Tan, Le Van, Jantarabenjakul, Watsamon, Sawitri, Anak Agung Sagung, Chantasrisawad, Napaporn, Yee, Sidney, Weng, Ruifen, Sundar, Raghav, Tan, Chee Wah, Wang, Lin-Fa, Sam, I-Ching, Young, Barnaby Edward, Sutarsa, I Nyoman, Chan, Yoke Fun

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Profiling microbial communities in idiopathic granulomatous mastitis by Ong, Seeu Si, Xu, Jia, Sim, Choon Kiat, Khng, Alexis Jiaying, Ho, Peh Joo, Kwan, Philip Kam Weng, Ravikrishnan, Aarthi, Tan, Benita Kiat-Tee, Tan, Qing Ting, Tan, Ern Yu, Tan, Su-Ming, Putti, Thomas Choudary, Lim, Swee Ho, Tang, Serene Ee Ling, Nagarajan, Niranjan, Karnani, Neerja, Li, Jingmei, Hartman, Mikael

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Modifiable risk factor score and fecundability in a preconception cohort in Singapore by Loy, See Ling, Ku, Chee Wai, Tiong, Michelle Mei Ying, Ng, Carissa Shi Tong, Cheung, Yin Bun, Godfrey, Keith M., Lim, Shan Xuan, Colega, Marjorelee T., Lai, Jun Shi, Chong, Yap-Seng, Shek, Lynette Pei-Chi, Tan, Kok Hian, Chan, Shiao-Yng, Chong, Mary Foong-Fong, Yap, Fabian, Chan, Jerry Kok Yen

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Correlates of lifestyle patterns among children in Singapore aged 10 years: the growing up in Singapore towards healthy outcomes (GUSTO) study by Tan, Sarah Yi Xuan, Chia, Airu, Tai, Bee Choo, Toh, Jia Ying, Colega, Marjorelee, Padmapriya, Natarajan, Setoh, Peipei, Kee, Michelle Zhi Ling, Yuan, Wen Lun, Lee, Yung Seng, Loo, Benny Kai Guo, Yap, Fabian Kok Peng, Tan, Kok Hian, Godfrey, Keith M., Chong, Yap Seng, Eriksson, Johan, Müller-Riemenschneider, Falk, Chong, Mary Foong-Fong

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Materials cartography: A forward-looking perspective on materials representation and devising better maps by Torrisi, Steven B., Bazant, Martin Z., Cohen, Alexander E., Cho, Min Gee, Hummelshøj, Jens S., Hung, Linda, Kamat, Gaurav, Khajeh, Arash, Kolluru, Adeesh, Lei, Xiangyun, Ling, Handong, Montoya, Joseph H., Mueller, Tim, Palizhati, Aini, Paren, Benjamin A., Phan, Brandon, Pietryga, Jacob, Sandraz, Elodie, Schweigert, Daniel, Shao-Horn, Yang, Trewartha, Amalie, Zhu, Ruijie, Zhuang, Debbie, Sun, Shijing

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Ultrahigh electromechanical response from competing ferroic orders by Lin, Baichen, Ong, Khuong Phuong, Yang, Tiannan, Zeng, Qibin, Hui, Hui Kim, Ye, Zhen, Sim, Celine, Yen, Zhihao, Yang, Ping, Dou, Yanxin, Li, Xiaolong, Gao, Xingyu, Tan, Ivan Chee Kiang, Lim, Zhi Shiuh, Zeng, Shengwei, Luo, Tiancheng, Xu, Jinlong, Tong, Xin, Li, Patrick Wen Feng, Ren, Minqin, Zeng, Kaiyang, Sun, Chengliang, Ramakrishna, Seeram, Breese, Mark B. H., Boothroyd, Chris, Lee, Chengkuo, Singh, David J., Lam, Yeng Ming, Liu, Huajun

“…These films show effective piezoelectric coefficients above 5,000 pm V-1 because of electric-field-induced antiferroelectric-ferroelectric phase transitions. …”
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Metabolite profiling in identifying metabolic biomarkers in older people with late-onset type 2 diabetes mellitus by Tam, Zhi Yang, Ng, Sean Pin, Tan, Ling Qiao, Lin, Chih-Hsien, Rothenbacher, Dietrich, Klenk, Jochen, Boehm, Bernhard Otto, Goh, Kelvin Kau Kiat, Suwanchaikasem, Pipob, Tipthara, Pornpimol, Koenig, W., Riepe, M., Peter, R., Geiger, H., Ludolph, A., Arnim, C. v., Denkinger, M. D., Yang, Song Yi, Nagel, G., Weinmayr, G., Rapp, K., Dallmeier, D., Steinacker, J. M., Laszlo, R., Becker, T., Stingl, J.

“…Lower levels of phenylalanine, acetylhistidine, and cyclic adenosine monophosphate (cAMP) were found in urine samples of T2D subjects validated with commercial standards. Elevated levels of 5′-methylthioadenosine (MTA), which previously has only been implicated in animal model of diabetes, was found in urine of older people with T2D.…”
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Northern gene flow into southeastern East Asians inferred from genome-wide array genotyping by He, Guang-Lin, Li, Ying-Xiang, Zou, Xing, Yeh, Hui-Yuan, Tang, Ren-Kuan, Wang, Pei-Xin, Bai, Jing-Ya, Yang, Xiao-Min, Wang, Zheng, Guo, Jian-Xin, Chen, Jin-Wen, Chen, Jing, Yang, Mei-Qing, Zhao, Jing, Sun, Jin, Zhu, Kong-Yang, Ma, Hao, Wang, Rui, Yang, Wen-Jiao, Hu, Rong, Wei, Lan-Hai, Hou, Yi-Ping, Wang, Meng-Ge, Chen, Gang, Wang, Chuan-Chao

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Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation by Li, Guoliang, Ruan, Xiaoan, Auerbach, Raymond K., Sandhu, Kuljeet Singh, Zheng, Meizhen, Wang, Ping, Poh, Huay Mei, Goh, Yufen, Lim, Joanne, Zhang, Jingyao, Sim, Hui Shan, Peh, Su Qin, Mulawadi, Fabianus Hendriyan, Ong, Chin Thing, Orlov, Yuriy L., Hong, Shuzhen, Zhang, Zhizhuo, Landt, Steve, Raha, Debasish, Euskirchen, Ghia, Wei, Chia-Lin, Ge, Weihong, Wang, Huaien, Davis, Carrie, Fisher-Aylor, Katherine I., Mortazavi, Ali, Gerstein, Mark, Gingeras, Thomas, Wold, Barbara, Sun, Yi, Cheung, Edwin, Liu, Edison, Sung, Wing-Kin, Snyder, Michael, Ruan, Yijun, Fullwood, Melissa Jane

“…Using genome-wide Chromatin Interaction Analysis with Paired-End-Tag sequencing (ChIA-PET), we mapped long-range chromatin interactions associated with RNA polymerase II in human cells and uncovered widespread promoter-centered intragenic, extragenic, and intergenic interactions. …”
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