Microfluidic platform for negative enrichment of circulating tumor cells by Sajay, Bhuvanendran Nair Gourikutty, Chang, Chia-Pin, Ahmad, Hamizah, Khuntontong, Puttachat, Wong, Chee Chung, Wang, Zhiping, Puiu, Poenar Daniel, Soo, Ross, Rahman, Abdur Rub Abdur

“…This negative enrichment method employs upstream immunomagnetic depletion to deplete CD45-positive WBCs followed by a microfabricated filter membrane to perform chemical-free RBC depletion and target cells isolation. Experiments of spiking two cell lines, MCF-7 and NCI-H1975, in the whole blood show an average of >90 % cell recovery over a range of spiked cell numbers. …”
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Calcined bone provides a reliable substrate for strontium isotope ratios as shown by an enrichment experiment by Snoeck, C, Lee-Thorp, J, Schulting, R, de Jong, J, Debouge, W, Mattielli, N

“…<p><b>Results</b></p> The strontium isotopic ratios of all samples immersed in the spiked solution were strongly modified showing that significant amounts of strontium had been adsorbed or incorporated. …”

Application of Fourier transform infrared spectroscopy to determine free fatty acid contents in palm olein by Che Man, Y.B., Setiowaty, G.

“…This set was prepared by spiking increasing amounts of oleic acid into a series of palm oleins that covers a wide range of FFA (0.08-1.04%). …”
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Discovering and forecasting extreme events via active learning in neural operators by Pickering, Ethan, Guth, Stephen, Karniadakis, George Em, Sapsis, Themistoklis P

“…Extreme events in society and nature, such as pandemic spikes, rogue waves or structural failures, can have catastrophic consequences. …”
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Impact of free nitrous acid shock and dissolved oxygen limitation on nitritation maintenance and nitrous oxide emission in a membrane bioreactor by Jiang, Yishuai, Poh, Leong Soon, Lim, Choon-Ping, Ng, Wun Jern

“…The strategy developed in this study verified that spiked FNA shock together with DO limitation can be used for maintaining nitritation in MBRs with long SRTs. …”
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Culture of human pluripotent stem cells and neural networks in 3D using an optogenetic approach and a hydrogel model by Lee, S

“…Interestingly, ChR2-YFP expression of Axol and SY5Y cells was detectable when transferred to the 3D culture system.…”

Impostor syndrome and pretense by Levy, N

“…I argue that we are especially likely to notice pretense when we’re made self-conscious, and that failing to match the stereotype of one’s profession or domain of expertise tends to give rise to self-consciousness. …”

Quality of life and healthcare service utilization among methadone maintenance patients in a mountainous area of Northern Vietnam by Nguyen, Long Hoang, Nguyen, Lan Huong Thi, Boggiano, Victoria L., Hoang, Canh Dinh, Van Nguyen, Hung, Le, Huong Thi, Le, Hai Quan, Tran, Tho Dinh, Tran, Bach Xuan, Latkin, Carl A., Zary, Nabil, Vu, Minh Thuc Thi

“…Being more highly educated, suffering acute diseases, and using health service within the last 12 months were associated with a decreased EQ-5D index. Individuals who were multiple substance abusers and those who recently had inpatient care were more likely to have a lower VAS. …”
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Universality for the largest eigenvalue of sample covariance matrices with general population by Bao, Zhigang, Pan, Guangming, Zhou, Wang

“…Moreover, in the real case, we show that when E is spiked with a fixed number of subcritical spikes, the type 1 Tracy—Widom limit TWi holds for the normalized largest eigenvalue of WN, which extends a result of Féral and Péché in [J. …”
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The effects of different solubilizing agents on the transport and pharmacokinetic profiles of indomethacin: in vitro and in vivo approach by Siti Aisyah Zainuddin, Abdul Latip Ab Hamid, Aqila Iman Rafandi, Mashani Mohamad, Khuriah Abdul Hamid, Syed Haroon Khalid

“…Solubilizing agents, including propylene glycol, Transcutol P, Labrasol, PEG 400, and Tween 80, were separately added at 10% (v/v) to 1 mg/5 mL for in vitro diffusion chamber and 10 mg/kg body weight for in vivo oral absorption studies of indomethacin. …”
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Simulation expectation by Thomas, T

“…I present a new argument that we are much more likely to be living in a computer simulation than in the ground-level of reality. …”

15.270 Ethical Practice: Professionalism, Social Responsibility, and the Purpose of the Corporation, Spring 2010 by Hafrey, Leigh

“…Over the course of thirteen sessions, students explore theoretical concepts in business ethics, and cases representing the challenges they will likely face as managers. Individual sessions take the form of moderated discussion, with occasional short lectures from instructor.…”
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Low-Cost Electronic Microfluidics for Multiplexed Point-of-Care Biomarker Detection by Kikkeri, Kruthika

“…It was validated by measuring spiked IL-6 concentrations in human blood, with applications demonstrated in CAR-T patient monitoring and small molecule detection for drug regulation. …”
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Development and validation of multiplex real-time PCR for simultaneous detection of six bacterial pathogens causing lower respiratory tract infections and antimicrobial resistance... by Dung, TTN, Phat, VV, Vinh, C, Lan, NPH, Phuong, NLN, Ngan, LTQ, Thwaites, G, Thwaites, L, Rabaa, M, Nguyen, ATK, Duy, PT

“…The reproducibility, linearity, limit of detection (LOD) of real-time PCR assays for pathogen detection were evaluated using DNA control mixes and spiked tracheal aspirate. The performance of RT-PCR assays was subsequently compared with the gold standard, conventional culture on 50 tracheal aspirate and sputum specimens of ICU patients.…”

High Rake Angle Orthogonal Machining of Highly Ordered Pyrolytic Graphite Parallel to the Basal Plane by Jayasena, B., Subbiah, S., Reddy, C. D.

“…Evidence of flat, folded, and rolled structures were found in exfoliated graphite sheets in addition to defects such as two types of kink bands. Multiple spikes in measured cutting forces were seen during machining due to disturbances in tool movement. …”
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Towards an optimal and unbiased approach for tumor cell isolation by Sajay, Bhuvanendran Nair Gourikutty, Chang, Chia-Pin, Ahmad, Hamizah, Chung, Wong Chee, Puiu, Poenar Daniel, Rahman, Abdur Rub Abdur

“…This approach achieves an average of >90 % recovery of spiked tumor cells and >99 % total WBC depletion in whole blood across multiple cell lines, in a simple and easy-to-use assay. …”
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Negative cognitions about the self in patients with persecutory delusions: An empirical study of self-compassion, self-stigma, schematic beliefs, self-esteem, fear of madness, and... by Collett, N, Pugh, K, Waite, F, Freeman, D

“…This study shows marked negative self cognitions in patients with persecutory delusions. These are likely to prove targets of clinical interventions, with patient preference most likely determining the best conceptualisation of negative self cognitions for clinicians to use.…”

The formation and evolution of Earth’s inner core by Wilson, AJ, Davies, CJ, Walker, A, Pozzo, M, Alfé, D, Deuss, A

“…In this review we assess the impact of supercooling on inner core forma5on, growth, dynamics, and the interpretation of seismic and paleomagnetic observations. …”

Characterization of hippocampal CA1 place cells. by Lau, Hwee Hui.

“…Most of the neurons had stable firing across sessions recorded in both familiar and novel environments, while some showing selective discharged of spikes in either one of the environments tested. The data recorded had provided spatial-temporal pattern for study of neuronal activities of physiologically identified place cells residing in the hippocampal CA1 pyramidal layer.…”
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ALMA spectral survey of Supernova 1987A – molecular inventory, chemistry, dynamics and explosive nucleosynthesis by Matsuura, M, Indebetouw, R, Woosley, S, Bujarrabal, V, Abellán, F, McCray, R, Kamenetzky, J, Fransson, C, Barlow, M, Gomez, H, Cigan, P, De Looze, I, Spyromilio, J, Stavely-Smith, L, Zanardo, G, Roche, P, Larsson, J, Viti, S, Van Loon, J, Wheeler, J, Baes, M, Chevalier, R, Lundqvist, P, Marcaide, J, Dwek, E, Meixner, M, Ng, C, Sonneborn, G, Yates, J

“…We find a dip in the J = 6–5 and 5–4 SiO line profiles, suggesting that the ejecta morphology is likely elongated. …”