Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin by Woetmann, Anders, Alhede, Morten, Dabelsteen, Sally, Bjarnsholt, Thomas, Rybtke, Morten, Nastasi, Claudia, Krejsgaard, Thorbjørn, Andersen, Mads Hald, Bonefeld, Charlotte M., Geisler, Carsten, Givskov, Michael, Odum, Niels

“…Here we show that (i) skin T cells in chronic wounds infected with S. aureus express interleukin-26 (IL-26) in situ, (ii) staphylococcal enterotoxins (SE) trigger IL-26 expression in T cell lines and primary skin T cells, and (iii) IL-26 triggers death and inhibits biofilm formation and growth of S. aureus. …”
Get full text
Get full text

Systems medicine disease : disease classification and scalability beyond networks and boundary conditions by Berlin, Richard, Gruen, Russell, Best, James

“…When Disease is viewed beyond the thresholds of lines and threshold boundaries, disease definition is not only the result of reductionist, mechanistic categories which reluctantly face re-composition. …”
Get full text
Get full text

Entangled exclusions: borders, frontiers and urban geopolitics from northeast India by Das, P, Mittal, G, Sarma, J

“…These have, in turn, led to further displacement, enclavization, and ghettoization of minority communities who are deemed ‘non-native’ along ethnocentric lines. Taking two cases from Shillong and Guwahati, we introduce the concept of entangled exclusions to analyse the layered, intertwined, multi-scalar nature of divides within these frontier cities. …”

Currency Crisis : The Next One in ASEAN? by Lim, Christopher H., Tan, Ming Hui

“…The impact of such currency turmoil would likely be more severe than the 1997-98 Asian Financial Crisis.…”
Get full text
Get full text

Indonesia : new haven for cybercriminals? by Senol Yilmaz

“…A close examination, however, reveals that such traffic may not originate in Indonesia. More likely, Indonesian networks are exploited by outside e-criminals.…”
Get full text
Get full text

RCEP : Another Missed Deadline by Pitakdumrongkit, Kaewkamol

“…However, the headway in the first half of 2019 is likely to be slow due to elections in some states.…”
Get full text
Get full text

Comment to U.S Copyright Office on Data Provenance and Copyright by Mahari, Robert, Shayne, Longpre, Donewald, Lisette, Polozov, Alan, Pentland, Alex 'Sandy', Lipsitz, Ari

“…Supervised datasets may likely contain copyrightable contributions from the dataset creators in the form of annotations. …”
Get full text

Unlocking the mysteries behind baby viral videos. by Chung, You Lun., Tan, Peck Lim., Sia, Shang Ying.

“…Contrary to our initial findings, funny baby videos are actually more likely to be shared as opposed to purely adorable ones. …”
Get full text

Precursors and correlates of transient and persistent longitudinal profiles of psychotic experiences from late childhood through early adulthood by Rammos, A, Sullivan, SA, Kounali, D, Jones, HJ, Hammerton, G, Hines, LA, Lewis, G, Jones, PB, Cannon, M, Thompson, A, Wolke, D, Heron, J, Zammit, S

“…Thus, it might be that the severity of exposure, rather than the presence of specific disease-modifying factors, is most likely to determine whether psychotic experiences are transient or persist, and potentially develop into a clinical disorder over time.…”

Putting distance through cleansing : the mediating role of temporal distancing on the embodiment of moral purity by Nurul Mira Fatin Abdulkahar

“…More specifically, it is hypothesized that compared to individuals who do not clean their hands, those who do so after recalling a past immoral act would be more likely to temporally distance their present selves away from their past immoral selves so as to preserve favorable self-view, and hence are more likely to perceive their past moral transgressions as less severe than they would have normally believed. …”
Get full text

The risk management of unemployment. by Chan, Han Eng., Ling, Julian., Sim, Rodney Boon Hian.

“…Her population is greying. Singapore is likely to undergo a lot of changes, be it the social environment or the economic environment. …”
Get full text

Who inadvertently shares deepfakes? Analyzing the role of political interest, cognitive ability, and social network size by Saifuddin Ahmed

“…The findings suggest that those with higher political interests are more likely to share deepfakes inadvertently. Those with lower cognitive ability are also more likely to share deepfakes inadvertently. …”
Get full text

What might ASEAN expect from Biden? by Tan, See Seng

“…But for the ASEAN region, Biden’s approach will likely be characterised by both change and continuity relative to that of the Trump administration.…”
Get full text

South China Sea Disputes: Nearing a Solution - Or Is It? by Ghosh, P. K.

“…The likely announcement by Philippine President Duterte of the Scarborough Shoal as an environmental marine sanctuary and off limits to fishermen could prove to be the first incremental step towards defusing the South China Sea disputes and in the process endow considerable strategic advantages to Beijing.…”
Get full text
Get full text

Indonesia's rise & its regional implications by Emirza Adi Syailendra

“…Indonesia's projected rise as a medium power may see at least two likely scenarios. The first is one of power diffusion while the second sees Indonesia asserting a greater leadership role in the Asia Pacific. …”
Get full text
Get full text

Navigating US-ASEAN economic relations after the 2024 US presidential election by Pitakdumrongkit, Kaewkamol, Wester, Shay

“…Two distinct paths based on the election outcome are outlined with recommendations for ASEAN to navigate the likely scenarios.…”
Get full text

3D spheroid-microvasculature-on-a-chip for tumor-endothelium mechanobiology interplay by Zhang, Yingqi, Jiang, Fengtao, Zhao, Charles Yunduo, Cho, Ann-Na, Fang, Guocheng, Cox, Charles D., Zreiqat, Hala, Lu, Zu Fu, Lu, Hongxu, Ju, Arnold Lining

Get full text

Automatic metric 3D surface mesh generation using subdivision surface geometrical model. Part 1 : construction of underlying geometrical model by Lee, Chi King

“…By using the subdivision surface concept, the new mesh generator can generate finite element meshes to model a wide range of surfaces which may contain sharp features such as cusp points and crease lines. When comparing with other traditional algorithms which use analytical surface patches as the underlying geometrical model, the new mesh generation scheme can be used in applications such as large deformation or crack analyses in which the domains to be gridded are not well defined or involve changing boundaries. …”
Get full text
Get full text

Critical role for cold shock protein YB-1 in cytokinesis by Mehta, Sunali, Algie, Michael, Al-Jabry, Tariq, McKinney, Cushla, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Ma, Weini, Zhang, Jessie, Bartolec, Tara K., Masamsetti, V. Pragathi, Parker, Kim, Henderson, Luke, Gould, Maree L., Bhatia, Puja, Harfoot, Rhodri, Chircop, Megan, Kleffmann, Torsten, Cohen, Scott B., Woolley, Adele G., Cesare, Anthony J., Braithwaite, Antony

“…Here, we found that YB-1 depletion in several cancer cell lines and in immortalized fibroblasts resulted in cytokinesis failure and consequent multinucleation. …”
Get full text

Study on supply chain challenges in container shipping : the port operator's perspectice by Muhammad Zulkarnain Mess.

“…Main challenges faced by port operators highlighted in the report include the ever increasing size of vessels, the chronic problem of port congestions and mergers and acquisitions of shipping lines. Some recommendations made for these problems are best practices adopted by ports world wide, while others such as ‘sharing concept’ are derived personally. …”
Get full text