Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds by Wamhoff, Eike-Christian, Ronsard, Larance, Feldman, Jared, Knappe, Grant A., Hauser, Blake M., Romanov, Anna, Case, James Brett, Sanapala, Shilpa, Lam, Evan C., Denis, Kerri J. St., Boucau, Julie, Barczak, Amy K., Balazs, Alejandro B., Diamond, Michael S., Schmidt, Aaron G., Lingwood, Daniel, Bathe, Mark

“…Here, we investigate thymus-independent DNA origami as an alternative material for multivalent antigen display using the receptor binding domain (RBD) of the SARS-CoV-2 spike protein, the primary target of neutralizing antibody responses. …”
Get full text

Rapid and Scalable Production of Functional SARS-CoV-2 Virus-like Particles (VLPs) by a Stable HEK293 Cell Pool by Puarattana-aroonkorn, Sitthiphol, Tharakaraman, Kannan, Suriyawipada, Disapan, Ruchirawat, Mathuros, Fuangthong, Mayuree, Sasisekharan, Ram, Artpradit, Charlermchai

“…We employed the membrane, envelope, and highly immunogenic spike proteins of SARS-CoV-2 to produce virus-like particles (VLPs) using the HEK293-F cell line as a host system with an economical transfection reagent. …”
Get full text

Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells by Carlevaro-Fita, Joana, Rahim, Anisa, Guigó, Roderic, Johnson, Rory, Vardy, Leah Karen Anne

“…Here we make a global, absolute estimate of the cytoplasmic and ribosome-associated population of stringently filtered lncRNAs in a human cell line using polysome profiling coupled to spike-in normalized microarray analysis. Fifty-four percent of expressed lncRNAs are detected in the cytoplasm. …”
Get full text
Get full text

Performance based automated control system design by Tan, Thiam Huat.

Get full text

Internet and internal communication of two public relations companies in Singapore: a case study approach by Fatmawati

Get full text

Impact of electronic commerce on consumer behaviour and attitude in Singapore. by Seah, Judy Bee Woon.

Get full text

Internet, participation, and protest potentials. by Yeo, Benjamin Jwee Kiat.

Get full text

New chiral ligands and catalysts for asymmetric synthesis by Xiao, Jian

Get full text

The role of p53 and ASPP2 in neurodegenerative disease by Turnquist, C

“…Also, LPS induces nuclear ASPP2 <em>in vivo</em> at the blood-cerebral spinal fluid-barrier (BCSFB), the brain's barrier to inflammation. …”

Singapore youth and their idols : celebrity workshop from a media and psychosocial perspective by Deng, Yihan, Lye, Peixian, Nai, Ying Jiin

Get full text

Computer, internet and you : hidden dangers you never knew. by Khoo, Li Mian., Tay, Dawn Kai Wen.

Get full text

Balance theory and the perception of religious relationships : an application of three quantitative cognitive consistency models in Singapore. by Lim, Wendy Mei Sze., Chua, Sha Ping.

Get full text

Nearest neighbor queries in spatial database by Liu, Danzhou.

Get full text

Efficient mining of group patterns for mobile users by Wang, Yida

Get full text

Reflections by Yu, Ming Dong

Get full text

Back to the Basics of SARS-CoV-2 Biochemistry: Microvascular Occlusive Glycan Bindings Govern Its Morbidities and Inform Therapeutic Responses by Scheim, David E., Parry, Peter I., Rabbolini, David J., Aldous, Colleen, Yagisawa, Morimasa, Clancy, Robert, Borody, Thomas J., Hoy, Wendy E.

“…Consistent with the biochemistry of coronaviruses as well established over decades, SARS-CoV-2 makes its initial attachment to host cells through the binding of its spike protein (SP) to sialylated glycans (containing the monosaccharide sialic acid) on the cell surface. …”
Get full text

NMDA receptor activation enhances inhibitory GABAergic transmission onto hippocampal pyramidal neurons via presynaptic and postsynaptic mechanisms by Xue, Jiu Gang, Masuoka, Takayoshi, Gong, Xian Di, Chen, Ken-Shiung, Yanagawa, Yuchio, Law, Alex Sai Kit, Konishi, Shiro

“…Thus NMDARs at glutamatergic synapses on both CA1 pyramidal neurons and interneurons appear to exert feedback and feedforward inhibition for determining the spike timing of the hippocampal microcircuit.…”
Get full text
Get full text

Commercialization of a web site, AsiaPhoto.com. by Cheong, Catherine Wai Shan.

Get full text

Are we apathetic? surveying Singaporeans' political attitudes, participation, and knowledge. by Chan, Boon Wee., Wong, Teck Zhung.

Get full text

Comparative advertising in Singapore : proposed amendments to the 1999 Singapore code of advertising practice (2nd Edition). by Ong, Lynn Pei Shan., Tian, Yee Shin.

Get full text