Estimating evolutionary and demographic parameters via ARG-derived IBD by Huang, Z, Kelleher, J, Chan, Y, Balding, D

“…Computational cost limits model complexity in our approach, but we are able to incorporate unknown nuisance parameters and model misspecification, still finding improved parameter inference.…”

Mitigating the challenges of distribution shift under strong computational constraints by Botos, C

“…The thesis also extends its investigation to online continual learning with label delay, proposing a novel approach to address the challenges of evolving data distributions and delayed feedback. The findings have significant implications beyond vision tasks, with the potential to impact a wide range of real-world applications. …”

Novel loci and biomedical consequences of iron homoeostasis variation by Allara, E, Bell, S, Smith, R, Keene, SJ, Gill, D, Gaziano, L, Morselli Gysi, D, Wang, F, Tragante, V, Mason, A, Karthikeyan, S, Lumbers, RT, Bonglack, E, Ouwehand, W, Roberts, DJ, Dowsett, J, Ostrowski, SR, Larsen, MH, Ullum, H, Pedersen, OB, Brunak, S, Banasik, K, Erikstrup, C, Mitchell, J

“…These associations were largely driven by HFE, which was associated with the largest iron variation. Our findings enhance understanding of iron homoeostasis and its biomedical consequences, suggesting that lifelong exposure to higher iron levels is likely associated with lower risk of anaemia-related disorders and higher risk of genitourinary, musculoskeletal, infectious and neoplastic diseases.…”

Rethinking urban street experiments through Lefebvre's rhythmanalysis: from vehicles and vibrancy to virtuosos by Chan, THY

“…Combining rhythmanalysis with spatial discourse analysis, the study ‘reads’ and ‘listens’ to temporary spaces through historical records (N = 55) of seven street experiments in Hong Kong from 2016 to 2020. Findings uncover the overly abstract agendas of these experiments — exemplified through narratives involving chairs, railings, and traffic signals — often oversimplify and exclude possibilities. …”

Literacy instruction from afar: evidence for the effectiveness of a remotely delivered language-rich reading programme by Downing, C, Evans-Jones, G, Calabrich, SL, Wynne, C, Cartin, R, Dunton, J, Elliott, R, Caravolas, M, Hulme, C, Jones, M

“…This study demonstrates that a remotely-delivered literacy programme is effective. These findings have important implications for delivering specialist literacy instruction at scale.…”

What is that I hear? An interdisciplinary review and research agenda for non‐native accents in the workplace by Hideg, I, Shen, W, Hancock, S

“…Second, we organize and integrate extant research findings using a 2 × 2 framework that incorporates the two main theoretical perspectives used to explain the effects of accents—stereotypes and processing fluency—and the two primary categories of workplace outcomes examined—interpersonal (i.e., others' evaluations of speakers with non-native accents, such as hiring recommendations) and intrapersonal (i.e., non-native-accented speakers' own evaluations and experiences, such as sense of belonging). …”

Homo europaeus: identity, bureaucracy and belonging in Brussels by Montgomery, S

“…It argues that Brussels-based European identity is not a delimited category anchored in specific points in time and space but an ‘elective identity’ that is a steppingstone to a global cosmopolitan manner of being in and interacting with the world. Its findings speak to an anthropological understanding of the conditions and possibilities for being European and belonging to Europe, where Europeanness emerges as an assertion of systemic integration in a turbulent geopolitical context marked by overlapping crises and enduring fragmentation.…”

Topological phase transition in quasi-one-dimensional bismuth iodide Bi 4 I 4 by Zhao, WX, Yang, M, Du, X, Li, YD, Zhai, KY, Hu, YQ, Han, JF, Huang, Y, Liu, ZK, Yao, YG, Zhuang, JC, Du, Y, Zhou, JJ, Chen, YL, Yang, LX

“…By tracking the temperature evolution of the (100) surface states, we unveil a thermal hysteresis of the surface gap in line with the α-β structural phase transition. Our findings directly evidence a temperature-induced topological phase transition from WTI to HOTI in Bi4I4, which paves the way to its potential applications at room temperature.…”

Dysregulation of MMP2-dependent TGF-ß2 activation impairs fibrous cap formation in type 2 diabetes-associated atherosclerosis by Singh, P, Sun, J, Cavalera, M, Al-Sharify, D, Matthes, F, Barghouth, M, Tengryd, C, Dunér, P, Persson, A, Sundius, L, Nitulescu, M, Bengtsson, E, Rattik, S, Engelbertsen, D, Orho-Melander, M, Nilsson, J, Monaco, C, Goncalves, I, Edsfeldt, A

“…This is regulated by free transforming growth factor-ß2 which is affected by hyperglycemia. Our findings underscore the importance of transforming growth factor-ß2-driven fibrous repair in type 2 diabetes as an area for future therapeutic strategies.…”

Ideology, language and the politics of time by Ewing, A

“…From the standpoint of ideology studies, it incorporates methods and findings in conceptual history and in the work of Reinhart Koselleck, the primary theorist in the field, to the study of political thinking. …”

Harnessing ultrasound-derived hydroxyl radicals for the selective oxidation of aldehyde functions by Fischer, AF, Bahry, T, Xie, Z, Qian, K, Li, R, Kwan, J, Jerome, F, Valange, S, Liu, W, Amaniampong, PN, Choksi, TS

“…Leveraging such pH and frequency effects is crucial to mitigating product degradation by secondary reactions with hydroxyl radicals and oxidation products (specifically hydrogen peroxide and superoxide). These findings demonstrate the potential of ultrasound as a driver for the selective oxidation of aldehyde functions to carboxylic acids, offering a sustainable route for valorizing biomass-derived platform molecules.…”

Exploring China’s cyber sovereignty concept and artificial intelligence governance model: a machine learning approach by Hung, HT

“…Therefore, this article applies topic modelling to official/semi-official texts about cyber and AI governance to understand the cyber sovereignty concept and how it shapes China’s approach to AI governance. This article finds that cyber sovereignty is an extension of China’s state-centric view of international order. …”

An antibody cocktail targeting two different CD73 epitopes enhances enzyme inhibition and tumor control by Xu, J, Chen, S, He, Y, Zhu, X, Wang, Y, Ye, Z, Zhou, JC, Wu, X, Zhang, L, Ren, X, Jia, H, Yu, H, Wei, X, Feng, Y, Chen, X, Cui, X, Pan, X, Wang, S, Xia, S, Shang, H, Pu, Y, Xu, W, Li, H, Chen, Q

“…In various animal models of syngeneic and xenograft tumors, HB0045 inhibits tumor growth more potently than the single mAbs. Collectively, our findings provide functional and structural insights into the mechanism of a CD73-targeting antibody cocktail.…”

Making the world a better place? English higher education and global public good by Marginson, S, Yang, L, Brotherhood, T

“…Interviewees included leaders and faculty in three universities, policy makers/regulators, national higher education organisations, and academic experts on higher education. The findings are interpreted in terms of theorisations of global spatiality and global public good. …”

Express: Learning new words via reading: the influence of emotional narrative context on learning novel adjectives by Dong, Y, Mak, MH, Hepach, R, Nation, K

“…Results from sentence completion and valence judgment were mixed, depending on the task demands. These findings are discussed with reference to theories of affective embodiment and the implications for learning abstract words are considered.…”

Paired analysis of host and pathogen genomes identifies determinants of human tuberculosis by Luo, Y, Huang, C, Howard, NC, Wang, X, Liu, Q, Li, X, Zhu, J, Amariuta, T, Asgari, S, Ishigaki, K, Calderon, R, Raman, S, Ramnarine, AK, Mayfield, JA, Moody, DB, Lecca, L, Fortune, SM, Murray, MB, Raychaudhuri, S

“…While the prevalence of the interacting strain almost doubled between 2010 and 2020, its infection is not associated with rs3130660 in this recent cohort. These findings suggest a complex interplay among host, pathogen, and environmental factors in tuberculosis dynamics.…”

The Pandemic EVIDENCE Collaboration Pillar 3: practice and policy by Leal, J, Byambasuren, O, Richards, G, Maltoni, S, Stelfox, T, Fiest, K, Bartoszko, J

“…There is also a clear need to improve the communication of scientific findings and evidence to enable more effective decision-making, especially about how scientists can most effectively advise governments. …”

Investor behavioral intention in investment-based crowdfunding: a systematic literature review by Astiwi Indriani, Aisyah Abdul Rahman, Shifa Mohd Nor, Nur Sa’adah Muhamad

“…By establishing an insightful foundation for future research and providing actionable insights for practitioners seeking to foster trust, manage risk, and harness both intrinsic and extrinsic motivations, our findings bear the potential to shape the evolution of investment-based crowdfunding in the coming years.…”
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Fintech renaissance: powering efficiency in Asian banking through country competitiveness by Mozaffar Alam Chowdhury, Soh, Wei Ni, Norhuda Abdul Rahim, Jalila Johari

“…The validated data satisfied the criteria for stationary, serial autocorrelation, heteroscedasticity, homogeneity, and multicollinearity. The findings show that Fintech significantly improves bank efficiency with the mediating effect of country competitiveness. …”
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A 10-year systematic review on the incorporation of digital games for multimodal literacy education by Shen, Yanan, Ab Jalil, Habibah, Jamaluddin, Rahimah

“…This study conducted a 10-year systematic review of 20 relevant empirical journal articles to provide a comprehensive understanding of utilizing digital games in multimodal literacy learning across primary, secondary, and higher education levels. The findings revealed the main contextual features, game features, theoretical and methodological perspectives, and the possibilities of digital games for multimodal literacy learning. …”
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