Circadian rhythm and misalignment in the pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD): an experimental medicine approach by Marjot, T

“…I show that 3-night shifts are associated with profound hepatic insulin resistance, a pathological hallmark of MASLD. This is likely to be related to a combination of circadian misalignment, sleep deprivation, and elevated light exposure during sleep. …”

Using cluster analysis to reconstruct dengue exposure patterns from cross-sectional serological studies in Singapore by Sangkaew, Sorawat, Tan, Li Kiang, Ng, Lee Ching, Ferguson, Neil M., Dorigatti, Ilaria

“…Conclusion: Cluster analysis is an unsupervised machine learning technique that can be applied to analyse PRNT antibody titres (without pre-established cut-off thresholds to indicate protection) to explore common patterns of DENV infection and infer the likely history of dengue exposure in a population.…”
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Synergy of compress strain and antioxidant of platinum-copper for enhanced the oxygen reduction performance by Zhang, Jun, Liang, Pingjuan, Xu, Xinlan, Wang, Rong, Liu, Shuyue, Wang, Chunyuan, Liu, Boyu, Luo, Laizheng, Jin, Meng, Liu, Huan, Yi, Huan, Lu, Shi-Yu

“…Herein, we report a worm-liked PtCu nanocrystals dispersed on nitrogen-doped carbon hollow microspheres (Pt0.38Cu0.62/N-HCS). …”
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Space weather radiation effects on geostationary satellite solid-state power amplifiers by Lohmeyer, W. Q., Cahoy, K. L.

“…Our observations suggest that internal charging from either past elevated radiation belt fluxes or some conditions related to relativistic electron enhancements (either causally or accidentally) is most likely responsible for the SSPA anomalies. We next consider the timing of these anomalies with respect to the local time (LT) and season. …”
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System-level design of low-carbon structures by Fang, Demi L.

“…“What is more likely to be associated with a reduction in emissions: switching from concrete to timber, or shortening the spans throughout the building?” …”
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Targeted hematopoietic stem cell depletion through SCF-blockade by Chan, Yan Y., Ho, Pui Y., Dib, Carla, Swartzrock, Leah, Rayburn, Maire, Willner, Hana, Ko, Ethan, Ho, Katie, Down, Julian D., Wilkinson, Adam C., Nakauchi, Hiro, Denis, Morgane, Cool, Taylor, Czechowicz, Agnieszka

“…Further, they highlight multiple approaches for efficacy in SCID settings and optimal combinations for WT settings. This work is likely to aid in the development of clinical non-genotoxic HSCT conditioning approaches that could benefit millions of people world-wide.…”
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Inclusions in calcite phantom crystals suggest role of clay minerals in dolomite formation by Farsang, Stefan, Pekker, Péter, Lampronti, Giulio I., Molnár, Zsombor, Milovský, Rastislav, Pósfai, Mihály, Ozdín, Daniel, Raub, Timothy D., Redfern, Simon Anthony Turner

“…While the micrometer-sized phyllosilicate and hematite particles were likely transported from the terra rossa and attached to the surface of growing calcite, the presence of phyllosilicates that are only a few atomic layers thick and of euhedral hematite, goethite, and dolomite crystals suggests that these particles precipitated along with the phantom calcite in situ, from an aqueous solution carrying terra rossa-derived and limestone-derived solutes. …”
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Outcomes of shoulder replacement surgery in routine care by Craig, RS

“…Patients aged over 85 years were far more likely to experience a serious adverse event (1 in 5 men and 1 in 10 women). …”

Preclinical development of antisense conjugates for the treatment of myotonic dystrophy 1 by Stoodley, J

“…It was concluded that this was likely due to the specific chemical properties of the compound rather than inherent limitations of anti-TfR1 antibodies, suggesting that further optimization of the conjugate’s chemical characteristics is necessary to improve therapeutic efficacy. …”

Introduction - Oxford Energy Forum – Issue, 98

“…Structural issues are likely to prevent any reversal of these trends in the years to come, unless radical reforms are enacted, as in the case of Mexico.…”

Dietary pattern trajectories in early childhood and their associations with patterns of maternal feeding practices in a multi-ethnic Asian cohort by Appannah, Geeta, Toh, Jia Ying, Lai, Jun Shi, Yong, Heng Yaw, Shariff, Zalilah Mohd, Tint, Mya Thway, Yuan, Wen Lun, Pang, Wei Wei, Godfrey, Keith M., Tan, Kok Hian, Yap, Fabian, Lee, Yung Seng, Eriksson, Johan G., Chong, Mary F. F.

“…Children whose mothers showed high adherence to the structured with autonomy support feeding practices at age 5 years were significantly more likely to be associated with the higher but decreasing ‘healthy’ DP trajectory group [OR = 3.62 (95% CI: 1.64, 7.99)]. …”
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3D bioprinting of high cell concentrations & cell spheroids to achieve physiologically relevant cell environments by Chua, Cliff Dun An

“…Results proved that the spheroids showed signs of growth and that the spheroids seemed to grow a liking to the alginate hydrogel be it the various concentrations of crosslinkers. …”
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Why do Chinese firms go public abroad and how do they perform? by Yuan, Mengying

“…The main finding is that overseas-listed companies do not perform better than A-share listed firms, but they are more likely to conduct M&A activities, financial investments, and bond issuance in currencies other than RMB. …”
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Effective and efficient topic mining and exploration from geo-textual data by Zhao, Kaiqi

“…Worse still, the existing methods are frequency-based (the more a topic is mentioned, the more likely a user prefers the topic), while ignoring the user’s sentiment. …”
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Use of Mid Upper-Arm Circumference (MUAC) as screening tool in an urban township in the Eastern Cape: rationale for testing changed cut-off values to identify malnutrition by McLaren, Shawn, Steenkamp, Liana, Venter, Danie

“…The least squares regression formula (Y = 15.409 + 0.803x (males); Y = 15.13 + 0.83x (females)) was then used to predict where WHZ = -2 is most likely to correspond with a MUAC value in cm. The new predicted MUAC values of 13.8 cm (males) and 13.5 cm (females) were subsequently tested for sensitivity and specificity. …”
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A systematic review of obsessive-compulsive disorder symptomatology in religious people of Abrahamic faiths: implications for clinical practice by Hassan, H

“…There remains a dearth of literature on the experiences of ethnic minority fathers in particular, who may be less likely to access psychological support available. …”

Development and validation of questionnaire on knowledge, attitudes, practices and perceived barriers related to nutrition care process among clinical dietitians in Malaysia by Bahari, Zaini

“…It was appeared that the practice of the NCP was likely to be influenced by the individual dietetics professionals and their administrators. …”
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Pregnant women admitted to hospital with covid-19 in 10 European countries: individual patient data meta-analysis of population based cohorts in International Obstetric Survey Syst... by Engjom, HM, de Bruin, O, Ramakrishnan, R, Aabakke, AJM, Äyräs, O, Deneux-Tharaux, C, Donati, S, Knight, M, Jonasdottir, E, Svanvik, T, Vercoutere, A, Vousden, N, Bleomenkamp, KWM

“…This finding indicates that national public health policies likely had a substantial and previously unrecognised role in protecting pregnant women. …”

Using machine learning to discover candidate localised transcripts from microscopy and genome-wide bioinformatics data by Kiourlappou, M

“…Using the adapted pipeline I predict 66 genes highly likely to be localised in glial cells protrusions and assess their functional and cellular attributes using GO enrichment. …”

Investigating the health and care needs of pregnant women with multiple long-term conditions by D'Arcy, R

“…MLTC was observed to be a common health concern among pregnant women, and is likely to become increasingly prevalent in the future. …”