Greener refrigerants by Hui, Harrison Jun Jie

“…Although many studies and experiments were carried out to improve the efficiency of the refrigeration cycles, most do not consider warm climates along with other localized factors like the stack effect. This study analyses the first and second law performance of seven refrigerants, R32, R1234yf, R134a, R1234ze(E), R404a, R401a and R744 at a evaporator temperature of 0°C and -32°C with varying condenser temperature of between 54.4°C and 70.0°C. …”
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Development of conductive cnts-filled polymeric nanocomposites produced via selective laser sintering by Ng, Yao Guang

“…Despite SLS process offering advantages such as abundant flexibilities in producing complex geometries, it also brought along constraints like the limited polymers that fit the bill for laser sintering. …”
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Fabrication of vascularized hydrogel construct through 3D printing by Neo, Frederik Wang Huang

“…Thus, vascularization in this case is the process of forming a distributed network of blood vessels much like that of a functional living organ, the purpose being to disseminate essential oxygen and nutrients in order for the cells to remain alive and functioning. …”
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Sec71 functions as a GEF for the small GTPase Arf1 to govern dendrite pruning of Drosophila sensory neurons by Wang, Yan, Zhang, Heng, Shi, Meng, Liou, Yih-Cherng, Lu, Lei, Yu, Fengwei

“…We further identified Sec71 as a guanine nucleotide exchange factor for Arf1 that preferentially interacts with its GDP-bound form. Like Arf1, Sec71 is also important for dendrite pruning, but not for apoptosis, of sensory neurons. …”
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Facile fabrication and characterization of multi-type carbon-doped TiO2 for visible light-activated photocatalytic mineralization of gaseous toluene by Zhang, Li, Tse, Man Siu, Tan, Ooi Kiang, Wang, Yu Xi, Han, Mandi

“…Raman, FTIR and XPS measurements revealed the presence of graphite-like carbon and the coexistence of substitutional and interstitial carbon in the TiO2 lattice. …”
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Ball with hair: modular functionalization of highly stable G-quadruplex DNA nano-scaffolds through N2-guanine modification by Lech, Christopher Jacques, Phan, Anh Tuân

“…Various chemistries including small modifications (N2-methyl-guanine), bulky aromatic modifications (N2-benzyl-guanine), and long chain-like modifications (N2-6-amino-hexyl-guanine) are tested and are found to be generally compatible with G-quadruplex formation. …”
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Urban flood detection with Sentinel-1 Multi-Temporal Synthetic Aperture Radar (SAR) observations in a Bayesian Framework : a case study for Hurricane Matthew by Lin, Nina Yunung, Yun, Sang-Ho, Bhardwaj, Alok, Hill, Emma M.

“…We identified smooth surfaces, like asphalt roads, and SAR shadows as the major sources of underprediction, and aquatic plants and soil moisture changes were the major sources of overprediction.…”
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Superconducting resonator and Rydberg atom hybrid system in the strong coupling regime by Yu, Deshui, Landra, Alessandro, Valado, María Martínez, Hufnagel, Christoph, Kwek, Leong Chuan, Amico, Luigi, Dumke, Rainer

“…Varying the electrostatic field brings the atomic-qubit transition on or off resonance with respect to the microwave resonator, leading to a strong atom-resonator coupling with an extremely large cooperativity. Like the nonlinearity induced by Josephson junctions in superconducting circuits, the large atom-resonator interface disturbs the harmonic potential of the resonator, resulting in an artificial two-level particle. …”
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Myristoylation restricts orientation of the GRASP domain on membranes and promotes membrane tethering by Heinrich, Frank, Nanda, Hirsh, Goh, Haw Zan, Bachert, Collin, Lösche, Mathias, Linstedt, Adam D.

“…The mammalian Golgi reassembly stacking protein (GRASP) proteins are Golgi-localized homotypic membrane tethers that organize Golgi stacks into a long, contiguous ribbon-like structure. It is unknown how GRASPs undergo trans pairing given that cis interactions between the proteins in the plane of the membrane are intrinsically favored. …”
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Quantitative evaluation of stone fragments in extracorporeal shock wave lithotripsy using a time reversal operator by Wang, Jen-Chieh, Zhou, Yufeng

“…The time reversal operator (TRO) method has the ability to detect point-like scatterers, and the number of non-zero eigenvalues of TRO is equal to that of the scatterers. …”
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Structural and functional characterisation of chikungunya virus replication complex dynamics by Tan, Yaw Bia

“…Through mosquito bites, the infected victims develop Chikungunya Fever (CHIKF) associated with symptoms like acute fever and painful polyarthritis. Unfortunately, there are no current effective antiviral drugs and vaccine treatments against CHIKV and many other +ssRNA viruses due to the inadequacy of biological information of its replication complex (RC) formations and the process of viral replications. …”
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Two types of new three-dimensional d–f heterometallic coordination polymers based on 2-(pyridin-3-yl)-1H Imidazole-4,5-dicarboxylate and oxalate ligands : syntheses, structures, lu... by Cai, Song-Liang, Zheng, Sheng-Run, Wen, Zhen-Zhen, Fan, Jun, Wang, Ning, Zhang, Wei-Guang

“…Complexes 1–5 are isostructural, exhibiting three-dimensional (3D) heterometallic networks with pcu topology based on the linkages of two-dimensional (2D) lanthanide–oxalate layers and pillar-like M(HPyIDC)2 (M = Fe, Co) subunits. Complexes 6–9 are also isomorphous and display another type of 3D heterometallic coordination framework built through the connections of 2D lanthanide–oxalate layers and one-dimensional (1D) Ag2(PyIDC)2 chains. …”
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Exploring the regulation of myofilament function in the heart using experimental and computational approaches by Folkmanaite, M

“…Dysregulation of cAMP-dependent, PKA-mediated phosphorylation of myofilament proteins, such as troponin I (TNI) and myosin binding protein C (MYBPC), contributes to cardiac pathologies like heart failure. Current therapies, such as beta-blockers and phosphodiesterase (PDE) inhibitors, often lack specificity and have adverse effects. …”

A population-based cohort study examining the incidence and impact of psychotic experiences from childhood to adulthood, and prediction of psychotic disorder by Sullivan, SA, Kounali, D, Cannon, M, David, AS, Fletcher, PC, Holmans, P, Jones, H, Jones, PB, Linden, DEJ, Lewis, G, Owen, MJ, O'Donovan, M, Rammos, A, Thompson, A, Wolke, D, Heron, J, Zammit, S

“…<p><strong>Methods:</strong></p> This was a population-based cohort study using the semistructured Psychosis-Like Symptoms Interview at ages 12, 18, and 24 (N=7,900 with any data). …”

Two-phase immersion cooling for power dense printed circuit board converters by Ristic-Smith, A

“…This is particularly important for applications like on-board chargers in electric vehicles, where compact magnetic components can lead to substantial reduction in volume for transformer isolated DC-DC converters.…”

Addressing inequities in research for early to mid-career women scientists in low- and middle-income countries: “Supporting Women in Science” programme by Das, JK, Raza, M, Padhani, ZA, Hussain, NF, Villar, J, Kennedy, S, Bhutta, ZA

“…Capacity-building initiatives like SWIS are crucial interventions to empower women scientists, foster equitable representation in academia, and create inclusive research environments and the programme acts as a steppingstone for future global leaders.…”

The critical role of IL-23 receptor positive T cells in the pathogenesis of anterior uveitis associated with spondyloarthropathy by Hedley, R

“…Consistent with the concept of IL-23 being a unifying factor in SpA, I show that like the gut, skin, and joints - IL-23 can also act locally on a resident IL-23 responsive cells to drive pathology within the eye.…”

Exploring the composition of placental microbiome and its potential origin in preterm birth by Saadaoui, M, Djekidel, MN, Murugesan, S, Kumar, M, Elhag, D, Singh, P, Kabeer, BSA, Marr, AK, Kino, T, Brummaier, T, McGready, R, Nosten, F, Chaussabel, D, Terranegra, A, Al Khodor, S

“…Additionally, it’s unclear whether the placental microbiome differs between healthy pregnancies and those with complications like preterm birth (PTB), which remains a leading cause of neonatal morbidity and mortality worldwide. …”

Clinical delineation and immunopathogenesis of autoimmune encephalitis by Varley, J

“…Finally, the underlying immunology in patients with AE secondary to leucinerich glioma inactivated protein-1 (LGI1) and contactin-associated protein-like 2 (CASPR2) antibodies remains unexplored and a likely source of novel, targeted immunotherapies.…”

Association between a selective 5-HT4 receptor agonist and incidence of major depressive disorder: emulated target trial by de Cates, AN, Harmer, CJ, Harrison, PJ, Cowen, PJ, Emmanuel, A, Travis, S, Murphy, SE, Taquet, M

“…Highly selective 5-HT4R agonists, such as prucalopride, have antidepressant-like and procognitive effects in preclinical models, but their clinical effects are not yet established. …”