Starvation, ferroptosis, and prodrug therapy synergistically enabled by a cytochrome c oxidase like nanozyme by Cao, Changyu, Yang, Nan, Su, Yan, Zhang, Zheye, Wang, Chenxi, Song, Xuejiao, Chen, Peng, Wang, Wenjun, Dong, Xiaochen

“…Herein, a cytochrome c oxidase-like nanozyme (copper-silver alloy nanoparticle, Cu-Ag NP) is demonstrated for nanocatalytic cancer therapy. …”
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Automated lesion segmentation and quantification for prediction of paradoxical worsening in patients with tubercular serpiginous-like choroiditis by Kalra, Gagan, Agarwal, Aniruddha, Marchese, Alessandro, Agrawal, Rupesh, Bansal, Reema, Gupta, Vishali

“…To develop and evaluate a fully automated pipeline that analyzes color fundus images in patients with tubercular serpiginous-like choroiditis (TB SLC) for prediction of paradoxical worsening (PW). …”
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Development of diamond-like carbon films for large area microelectronic applications using ECR-CVD by Yoon, Soon Fatt.

“…In this project, the ECR-CVD technique has been used to deposit amorphous and diamond-like carbon films from a mixture of hydrogen and methane, and for the characterisation of optical, structural and mechanical properties of the films, the following analytical techniques has been employed.…”
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Fabrication and packaging of piezoresistive MEMS pressure sensor array for passive fish-like underwater sensing by Chia, Mark Sebastian Xiong Wei.

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Human metapneumovirus in Singapore : epidemiology, fusion-attachment protein interaction and virus-like particle assembly by Loo, Liat Hui

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Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation by Jackman, Joshua Alexander, Linardy, Eric, Yoo, Daehan, Seo, Jeongeun, Ng, Wei Beng, Klemme, Daniel J., Wittenberg, Nathan J., Oh, Sang-Hyun, Cho, Nam-Joon

“…A plasmonic nanohole sensor for virus-like particle capture and virucidal drug evaluation is reported. …”
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DRD-UNet, a UNet-like architecture for multi-class breast cancer semantic segmentation by Ortega-Ruíz, Mauricio Alberto, Karabağ, Cefa, Roman-Rangel, Edgar, Reyes-Aldasoro, Constantino Carlos

“…This paper describes a UNet-like deep learning architecture called DRD-UNet, which adds a novel processing block called DRD (Dilation, Residual, and Dense block) to a UNet architecture. …”
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Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines by Sherry, L, Bahar, MW, Porta, C, Fox, H, Grehan, K, Nasta, V, Duyvesteyn, HME, De Colibus, L, Marsian, J, Murdoch, I, Ponndorf, D, Kim, S, Shah, S, Carlyle, S, Swanson, JJ, Matthews, S, Nicol, C, Lomonossoff, GP, Macadam, AJ, Fry, EE, Stuart, DI, Stonehouse, NJ, Rowlands, DJ

“…Continued use of these vaccines, however, threatens ultimate disease eradication and achievement of a polio-free world. Virus-like particles (VLPs) that lack a viral genome represent a safer potential vaccine, although they require particle stabilization. …”

Bacteriocin-like peptides encoded by a horizontally acquired island mediate Neisseria gonorrhoeae autolysis by Poncin, K, McKeand, SA, Lavender, H, Kurzyp, K, Harrison, OB, Roberti, A, Melia, C, Johnson, E, Maiden, MCJ, Greaves, DR, Exley, R, Tang, CM

“…The nap island in the gonococcus encodes 3 cationic, bacteriocin-like peptides which have no detectable antimicrobial activity. …”

Distinct movement disorders in contactin-associated-protein-like-2 antibody-associated autoimmune encephalitis by Gövert, F, Abrante, L, Becktepe, J, Balint, B, Ganos, C, Hofstadt-van Oy, U, Krogias, C, Varley, J, Irani, SR, Paneva, S, Titulaer, MJ, de Vries, JM, Boon, AJW, Schreurs, MWJ, Joubert, B, Honnorat, J, Vogrig, A, Ariño, H, Sabater, L, Dalmau, J, Scotton, S, Jacob, S, Melzer, N, Bien, CG, Geis, C, Lewerenz, J, Prüss, H, Wandinger, K-P, Deuschl, G, Leypoldt, F

“…In the elderly, anti-LGI1 and contactin associated protein like 2 (CASPR2) antibody-associated diseases compose a relevant fraction of autoimmune encephalitis. …”

Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer by Alsaiari, Shahad K., Nadeef, Seba, Daristotle, John L., Rothwell, William, Du, Bujie, Garcia, Johnny, Zhang, Linzixuan, Sarmadi, Morteza, Forster, Timothy A., Menon, Nandita, Lin, Stacey Qiaohui, Tostanoski, Lisa H., Hachmann, Nicole, Wang, Erika Yan, Ventura, John D., Barouch, Dan H., Langer, Robert, Jaklenec, Ana

“…In this work, we report the Toll-like receptor agonist activity of a nanoscale adjuvant zeolitic imidazolate framework–8 (ZIF-8). …”
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Enriching the methanol generation via CO2 photoconversion over the cockscomb-like fibrous silica copper by Mahadi, Bahari, Che Rozid, Mamat, Aishah, Abdul Jalil, Shing, Lo Sook, Nurul Sahida, Hassan, F. F.A., Aziz, Alhassan, Mansur, Mohd Ghazali, Mohd Nawawi, Kamarizan, Kidam, Herma Dina, Setiabudi

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Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptors by Luo, Dahai

“…The RIG-I-like receptors (RLRs)—RIG-I, MDA5, and LGP2—detect intracellular pathogenic RNA and elicit an antiviral immune response during viral infection. …”
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Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration by James, Rachel E., Schalks, Renee, Browne, Eleanor, Eleftheriadou, Ioanna, Munoz, Carmen Picon, Mazarakis, Nicholas D., Reynolds, Richard

“…Here we tested the hypothesis that persistent production of these cytokines in the meningeal compartment and diffusion into underlying GM can drive chronic MS-like GM pathology. Lentiviral transfer vectors were injected into the sagittal sulcus of DA rats to deliver continuous expression of TNF + IFNγ transgenes in the meninges and the resulting neuropathology analysed after 1 and 2 months. …”
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Chrysanthemum-like Au@Polydopamine synthesized using one-pot method and its advantage in immunochromatographic assay by Zhang, Gang-gang, Lai, Xiao-cui, Ding, Neng-shui, Xiong, Qirong, Hou, Shuai, Duan, Hongwei, Lai, Wei-hua

“…Flower-like gold nanoparticle (AuNF) is widely used as a probe. …”
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Genes for carnivory : a comparative study on the local duplication of papain-like cysteine proteases in carnivorous plants by Tan, Qiao Wen

“…Thus, the presence of protein degrading enzymes such as papain-like cysteine proteases (PLCPs) in trap fluids is not surprising. …”
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Bio-inspired Flow Sensing and Prediction for Fish-like Undulating Locomotion: A CFD-aided Approach by Zhou, Han, Hu, Tianjiang, Low, Kin Huat, Shen, Lincheng, Ma, Zhaowei, Wang, Guangming, Xu, Haijun

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Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation by Schneikert, Jean, Chandra, Shree Harsha Vijaya, Ruppert, Jan Gustav, Ray, Suparna, Wenzel, Eva Maria, Behrens, Jürgen

“…Using RNA interference and domain swapping experiments, we show that APCL benefits from the 15R of truncated APC to target β-catenin for degradation, in a process likely involving heterodimerization of the two partners. …”
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Local rainfall is more likely than distant thunderstorms to affect movement behaviour in Northern Kenyan elephants by Mulder, T, Mortimer, B, Ferwerda, J, Vollrath, F

“…We conclude that climate change makes a strong case for studying elephant behaviours in response to environmental cues during the day and night, especially in dry-land study sites like Northern Kenya.…”

GOLDEN2-like1 is sufficient but not necessary for chloroplast biogenesis in mesophyll cells of C4 grasses by Lambret-Frotte, J, Smith, G, Langdale, J

“…In land plants, chloroplast biogenesis is regulated by a family of transcription factors named GOLDEN2-like (GLK). In C4 grasses, it has been hypothesized that genome duplication events led to the sub-functionalization of GLK paralogs (GLK1 and GLK2) to control chloroplast biogenesis in two distinct cell types: mesophyll and bundle sheath cells. …”