Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy by Zheng, SL, Henry, A, Cannie, D, Lee, M, Miller, D, McGurk, KA, Bond, I, Xu, X, Issa, H, Francis, C, De Marvao, A, Theotokis, PI, Buchan, RJ, Speed, D, Abner, E, Adams, L, Aragam, KG, Ärnlöv, J, Raja, AA, Backman, JD, Baksi, J, Barton, PJR, Biddinger, KJ, Boersma, E, Lindgren, CM

“…We demonstrate that polygenic scores predict DCM in the general population and modify penetrance in carriers of rare DCM variants. Our findings may inform the design of genetic testing strategies that incorporate polygenic background. …”

Single point mutations in ATP synthase compensate for mitochondrial genome loss in trypanosomes by Dean, S, Gould, MK, Dewar, CE, Schnaufer, AC

“…Our results provide insight into the molecular mechanism of compensation for kDNA loss by showing FO-independent generation of the mitochondrial membrane potential with increased dependence on the ADP/ATP carrier. Our findings also suggest that, in the pathogenic bloodstream stage of T. brucei, the huge and energetically demanding apparatus required for kDNA maintenance and expression serves the production of a single F1FO–ATPase subunit. …”

Vitamin D in Gambian children with discordant tuberculosis (TB) infection status despite matched TB exposure: a case control study by Stockdale, L, Sambou, B, Sissoko, M, Egere, U, Sillah, AK, Kampmann, B, Basu Roy, R

“…Mean vitamin D levels were 2.05 ng/mL (95% CI - 0.288 to 4.38) higher in 24 highly TB-exposed uninfected children compared with 24 matched highly TB-exposed infected children (p = 0.08). The findings warrant further investigation in larger studies to understand the implications and significance. …”

Disciplining the state: virtue, violence, and state-making in modern China by Thornton, P

“…Scholars of European history assert that war makes states, just as states make war. This study finds that in China, the challenges of governing produced a trajectory of state-building in which the processes of moral regulation and social control were at least as central to state-making as the exercise of coercive power. …”

Self-diagnosis of mental disorders: a qualitative study of attitudes on Reddit by Foulkes, L, Underhill, R

“…Together, these themes highlight that there is considerable anger, derision and criticism targeted towards people who self-diagnose with mental disorders, and that this is particularly targeted towards adolescents who self-diagnose on or as a result of social media. The findings have important implications for understanding how to support and validate people, particularly adolescents, who (sometimes accurately) use diagnostic language to express how they are feeling.…”

The impact of antibiotics on the gut microbiota of children recovering from watery diarrhoea by Le, S-NH, Nguyen Ngoc Minh, C, de Sessions, PF, Jie, S, Tran Thi Hong, C, Thwaites, GE, Baker, S, Pham, DT, Chung The, H

“…These changes included a pronounced, transient overabundance of Enterococcus species and depletion of Bifidobacterium pseudocatenulatum. Our findings demonstrate that antibiotic treatment slows gut microbiota recovery in children following watery diarrhoea.…”

Comparison of physics, chemistry and biology teachers’ perceptions of nature of science and domains of science by Kaya, E, Erduran, S

“…This observation is corroborated through some of the findings from the qualitative data analysis which provides detailed variations among the teachers indicating a complex set of relations between the similarities and differences among teachers’ perceptions across subject specialisms. …”

Addressing Factors that Impact Sexual Well-Being and Intimacy in IBD Patients by Elias, S, Nandi, N, Fourie, S, Grover, L, Newman, KL

“…Purpose of Review: This review details the pathophysiologic mechanisms from medical, surgical to psychosocial factors that illustrate how and why sexual health and intimacy are impacted in IBD. Recent Findings: Recent clinical surveys of practicing gastroenterologists document that clinicians should routinely address sexual health when addressing patient reported outcomes but very few actually make direct inquiry or suggest management into this important aspect of human life. …”

‘Swirling' around translanguaging spaces of nature of science in multilingual classrooms by Cheung, KKC, Erduran, S, Oancea, A

“…Furthermore, we articulate how linguistically diverse learners navigate within and across these two translanguaging spaces. Our findings indicate that the teacher and students discussed a network of NOS ideas using gestures, different named languages as well as visual resources within the NOS-negotiation space. …”

The (un)intended consequences of oil sanctions through the dark shipping of sanctioned oil by Bai, X, Fernández-Villaverde, J, Li, Y, Xu, L, Zanetti, F

“…China, leveraging discounted oil, boosts industrial output, propagating global economic shocks. Our findings expose dark shipping’s central role in reshaping oil markets and macroeconomic dynamics.…”

Quantitative energy storage and ejection release in superelastic shape memory alloy wire by Sui, WC, Pei, YC, Wang, BH, Liu, SJ, Wu, JT, Lu, H

“…In this paper, a revolutionary and yet explainable property of the SMA is investigated and confirmed: superelastic SMA energy storage and release can be quantitatively measured using electrical resistance. This finding boosted the SMA with significant advantages and potential in the field of mechanical energy storage and ejection release. …”

Identity through two lenses: the Slovak minority’s self and external views in Poland by Bryja, Marek

“…Employing a diagnostic survey method, the research investigates the perceptions of both Slovaks and Poles, offering a comparative analysis. The findings suggest that the core elements of the Slovak minority’s identity are rooted in language, traditions, culture, and religion. …”
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Exploring career realities: elevating graduate employability through job shadowing by Hanaliza Kamis, Phan, Jasmine Ah Kiaw, Sheela Karunaharan Thanaraj, Jen, Ling Gan

“…Upon completion, students present their findings to the organizations, then receive valuable feedback. …”
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Financial wellbeing of poor households: role of digital financial inclusion by Lu, Ming-Pey, Zunarni Kosim, Nora Azureen Abdul Rahman

“…The data were analyzed using PLS modeling techniques. The findings demonstrate that financial wellbeing is significantly determined by financial behavior, financial literacy, and digital financial inclusion. …”
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Pengintegrasian pemikiran komputasional melalui aplikasi mudah alih untuk meningkatkan disposisi pemikiran komputasional by Isra Khasyyatillah, Kamisah Osman, Hazrati Husnin

“…Additionally, it underscores the importance of CT elements in education to promote more inclusive teaching practices. Overall, the findings confirm the value of mobile learning applications in advancing CT in education.…”
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Exploring employers' perceptions on public universities' quality and graduate employability in Malaysia by Almasri, Amal Ahmad, Ali, Noor Azman, Jantan, Amer Hamzah

“…This study adopted a qualitative research design by using a semi- structural interview with ten employers. The findings indicate the determinants of university quality, including university outcomes, reputation, academic program and curriculum, infrastructure and support facilities, academic staff, and training as influential factors on graduate employability. …”

Re-narration in John Minford’s translation of Sun Tzu’s The Art of War by Zhang, Linyu, Mansor, Nor Shahila, Ghazali, Akmar Hayati Ahmad, Li, Mengduan

“…A sample of 671 translation instances from Chinese to English is analysed. The findings reveal that selective appropriation emerges as the primary framing strategy in commentary translation, while the repositioning of participants emerges as the most prominent framing strategy in re-narration.…”
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An improve unsupervised discretization using optimization algorithms for classification problems by Mohamed, Rozlini, Samsudin, Noor Azah

“…According to the experimental findings, the suggested EB has a major effect on the accuracy, recall, and F-measure of data classification. …”
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Effects of moisture content and temperature on microwave measurement of lightweight foamed concrete by Lee, Kim Yee, Phua, Yeong Nan, Lim, Siong Kang, You, Kok Yeow, Cheng, Ee Meng

“…Validation showed that the error was below 5 % for dielectric constant and below 8 % for loss factor at 5-GHz frequency. These findings have implications for the telecommunications industry and on-site moisture content measurements, with potential applications in building material engineering.…”

Measuring Sustainability of Takaful Performance in Malaysia by Che Arshad, Noraziah, Irijanto, Tubagus Thresna

“…It is expected that findings from this study will contribute to the existing literature to both theoretical and managerial approaches in order to better understand the pattern of performance for both local and foreign takaful companies in Malaysia…”
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