Investigating the role of factor inhibiting HIF (FIH) in tumourigenesis by Ma, J

“…Factor Inhibiting HIF (FIH), an oxygen-dependent hydroxylase of HIF, inhibits the transcription of selective HIF target genes, and is hence a potential therapeutic target to fine-tune HIF activity. However, how FIH may affect tumourigenesis has not been comprehensively investigated.…”

A driftwood-based record of Arctic sea ice during the last 500 years from northern Svalbard reveals sea ice dynamics in the Arctic Ocean and Arctic peripheral seas by Hole, GM, Rawson, T, Farnsworth, WR, Schomacker, A, Ingólfsson, Ó, Macias-Fauria, M

“…Provenance and age determinations by dendrochronology and wood anatomy provide insights into Arctic Ocean currents and climatic conditions at a fine spatial resolution, as crossdating with reference chronologies from the circum-Arctic boreal forests enables determination of the watershed the driftwood originated from. …”

Evaluating new malaria vaccine candidates by Noé, A

“…In a human efficacy study of prime-target vaccination, multi-omic analyses were performed on hepatic fine needle aspirates and peripheral blood samples to study liver TRM and their circulating counterparts. …”

Nebular dominated galaxies: insights into the stellar initial mass function at high redshift by Cameron, AJ, Katz, H, Witten, C, Saxena, A, Laporte, N, Bunker, A

“…Modelling the UV turnover with a DLA requires extreme column densities (𝑁HI > 1023 cm−2 ), and simultaneously explaining the high 𝑓esc,Ly𝛼 requires a fine-tuned geometry. In contrast, modelling the spectrum as primarily nebular provides a good fit to both the continuum and emission lines, motivating scenarios in which (a) we are observing only nebular emission or (b) the ionizing source is powering extreme nebular emission that outshines the stellar emission. …”

Integration of genetic data and genomic annotation in the analysis of genome wide association studies by Ng, E

“…An example of an identified association was that between serum apolipoprotein B levels and rs7412, which is consistent with other GWAS. To fine map these loci and assign functional annotation, I created Bayesian credible sets and checked for overlap between SNPs in these credible sets and regulatory marks in the Encyclopaedia of DNA Elements (ENCODE) database. …”

The structural, mechanical, and biological variation of silica bioglasses obtained by different sintering temperatures by Sarmast Sh, M., Dayang Radiah, A. B., Hoey, D. A., Abdullah, N.

“…These findings highlight the potential of fine-tuning the sintering temperature to modulate the crystallinity of bioglasses, thereby enhancing their application scope in bone tissue engineering.…”

Structural insights into cold-active lipase from Glaciozyma antarctica PI12: AlphaFold2 prediction and molecular dynamics simulation by Matinja, Adamu Idris, Ahmad Kamarudin, Nor Hafizah, Leow, Adam Thean Chor, Oslan, Siti Nurbaya, Mohamad Ali, Mohd Shukuri

“…Cold-active lipase applications are now growing in the detergency, synthesis of fine chemicals, food processing, bioremediation, and pharmaceutical industries. …”

Responses of gas exchange and growth in Merkus pine seedlings to expected climatic changes in Thailand by Koskela, Jarkko

“…A carbon-and nitrogen-balance growth model applied structural regularities of a tree and a modification of functional balance between foliage and fine roots as growth-guiding rules. Adaptation to local climates was incorporated in the models. …”

AI-powered COVID-19 forecasting: a comprehensive comparison of advanced deep learning methods by Tariq, Muhammad Usman, Ismail, Shuhaida

“…Bayesian optimization was also implemented to fine-tune these models. Results: The evaluation framework revealed that each model exhibited different levels of predictive accuracy and precision. …”
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AI-powered COVID-19 forecasting: a comprehensive comparison of advanced deep learning methods by Tariq, Muhammad Usman, Ismail, Shuhaida

“…Bayesian optimization was also implemented to fine-tune these models. Results: The evaluation framework revealed that each model exhibited different levels of predictive accuracy and precision. …”
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A Review of Genetic Algorithm: Operations and Applications by Md Isa, Faizatulhaida, Ariffin, Wan Nor Munirah, Jusoh, Muhammad Shahar, Erni Puspanantasari Putri, Erni Puspanantasari Putri

“…The conclusion underscores the enduring relevance of GA in the optimization landscape, emphasizing their potential to remain a pivotal tool for addressing intricate real-world challenges, provided their parameters are fine-tuned judiciously to balance exploration and exploitation.…”
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Potential of Pressmud Waste from Sugar Industry in Brick Manufacturing for Green Business and Sustainability by Mohamad, Maheera, Chong, Khai Lin, Abdul Nasir, Muhammad Hafeez, Abidin, Rahimi, Abu, Noor Hidayah, Razalli, Mohd Rizal, Taib, Che Azlan, Mohd Yusoff, Yuhainis, Chellamuthu, Vignes

“…This study investigates the feasibility of using pressmud, a sugarcane refinery waste, as a fine bio-aggregate for the production of construction materials. …”
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Synthesis and optical study of lead halide perovskites for opto-electronic applications by Ha, Son Tung

“…These methods usually result in polycrystalline film with many pin-holes and defects. As a physicist, my first aim is to find a way to prepare highest quality, single crystal samples for studying their intrinsic and fundamental properties. …”
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Investigating the EM performance of building materials for mid-band 5G in urban built environment: an exploratory study by Ng, Sean Jake Peng

“…This comprehensive study encompasses various factors, including the choice of aggregate types (FAC and fine sand), different levels of Fe2O3 inclusions (2 wt% and 4 wt%), and channel frequencies within the 3300 to 3800 MHz frequency band (divided into five 100 MHz channels). …”
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Research on basic mechanical properties of different modulus alkaline excited ECC by Che, Jialing, Yang, Renze, Wang, Jun, Liu, Haifeng, Hu, Yun xiang, Doh, Shu Ing

“…The effect of the alkali activator modulus on the mechanical properties and microstructure of two types of fiber-reinforced engineering cementitious composites (alkali-excited ECC) with desert sand as fine aggregate was studied. The alkali activator was prepared by a certain proportion of NaOH and sodium silicate mixture, and the mechanical performance indexes were used for analysis, including compressive/tensile/flexural strength, Poisson's ratio and elastic modulus, flexural toughness ratio and energy performance index (PSH). …”
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Optimizing crystal size distribution based on different cooling strategies in batch crystallization process by Siti Zubaidah, Adnan, Noor Asma Fazli, Abdul Samad

“…Furthermore, the number of fine crystals was among the lowest at a volume distribution of 0.00071 m3/m compared to the linear profile at 0.00191 m3/m. …”
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Morphology‐Directed Light Emission from Fluorescent Janus Colloids for Programmable Chemical‐To‐Optical Signal Transduction by Frank, Bradley D., Nagelberg, Sara, Baryzewska, Agata W., Simón Marqués, Pablo, Antonietti, Markus, Kolle, Mathias, Zeininger, Lukas

“…Informed by experimental observations of morphology‐dependent optical confinement of internally emitted light within the higher refractive index phases, ray‐tracing is used to predict and fine‐tune the droplets’ optical properties and their ability to concentrate light. …”
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0-1 Knapsack in Nearly Quadratic Time by Jin, Ce

“…Our algorithm combines and extends several recent structural results and algorithmic techniques from the literature on knapsacktype problems: (1) We generalize the “fine-grained proximity” technique of Chen, Lian, Mao, and Zhang (2023) derived from the additivecombinatorial results of Bringmann and Wellnitz (2021) on dense subset sums. …”
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User satisfaction and service quality improvement priority of bus rapid transit in Belo Horizonte, Brazil by Zheng, Yunhan, Kong, Hui, Petzhold, Guillermo, Barcelos, Mariana M, Zegras, Christopher P, Zhao, Jinhua

“…These findings can help policymakers fine-tune improvement strategies targeted at different types of services.…”
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Accurate and Fast Approximate Graph Mining at Scale by Arpaci-Dusseau, Anna

“…Hybrid sampling further improves performance by automatically choosing the better scheme between fine-grained and coarse-grained sampling schemes. …”
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