The emergence of DNAM-1 as the facilitator of NK cell-mediated killing in ovarian cancer by Pounds, R, Croft, W, Pearce, H, Hossain, T, Singh, K, Balega, J, Jeevan, DN, Sundar, S, Kehoe, S, Yap, J, Moss, P, Zuo, J

“…Expression of PVR, the DNAM-1 ligand, was significantly increased on tumours and DNAM-1 mediated NK cell lysis of primary tumour tissue was observed in vitro. Discussion: These findings reveal profound modulation of the tumour tissue and systemic profile of NK cells which likely contributes to the high rates of local progression and metastasis seen with OC. …”

Community responses to a novel house design: A qualitative study of “Star Homes” in Mtwara, southeastern Tanzania by Mshamu, S, Meta, J, Adhikari, B, Halifa, S, Mmbando, A, Wood, HS, Wood, OS, Bøjstrup, TC, Day, NPJ, Lindsay, SW, Knudsen, J, Deen, J, Seidlein, LV, Pell, C

“…Star Homes residents described how the structures triggered praise but also envy from other community members. Conclusions: The findings highlight the need for close attention to the use of novel design houses and careful sensitization around the potential benefits of dwellings to ensure that the intended health impacts of interventions are achieved.…”

Mendelian Randomization analysis of the causal effect of cigarette smoking on hospital costs by Dixon, P, Sallis, H, Munafo, M, Davey Smith, G, Howe, L

“…</p> <br> <p><strong>CONCLUSIONS:</strong> Our findings have implications for the potential cost-effectiveness of smoking interventions.…”

Of blood and belonging: the practice of antiretroviral treatment among HIV-positive youth in South Africa's Eastern Cape by Vale, B

“…Data for this study was gathered through eight months of multi-method ethnographic fieldwork with 23 HIV-positive youth, their families, and local health workers.</p> <p>The findings elucidate adolescent ART as a complex (and often volatile) form of social incorporation, through which young people negotiate survival, care and moral connection in contemporary South Africa. …”

Risk factors for PTSD symptoms following PICU admission for childhood septic shock by Corbet Burcher, GJ, O’Dea, LA, Cooper, MK, Lancaster, R, McCutcheon, RA, Garralda, ME, Nadel, S

“…PTS symptoms in children who have survived septic shock are prevalent. These findings support a possible contribution of acute inflammatory changes, cumulative traumatic exposure, and female gender in post-PICU PTSD development.…”

Unlocking the gates: pedestrian route choice in transforming metro station paid areas into mobile public spaces by Chan, HY, Tse, W-Y, Chen, A

“…Routes with proprietary underground exits also promote underground usages. These findings reveal how deliberate design, ingrained habits and symbolic meanings collectively shape pedestrian decisions. …”

Lebensphilosophie in Rabbi Avraham Itzhak HaCohen Kook’s thought: the case of Henri Bergson by Amati, G

“…It isolates relevant overlaps between Bergson's philosophy of life and Kook's thought, the findings are then leveraged to provide a new, deeper, and enriched interpretation of Kook's philosophy on these topics, and, in some cases, present original perspectives to resolve existing contradictions in his thought.…”

A generative model for evaluating missing data methods in large epidemiological cohorts by Radosavljević, L, Smith, SM, Nichols, TE

“…We compare our evaluations based on synthetic data to an exemplar study which includes variable selection on a single real imputed dataset, finding only small differences between the imputation methods though with iterative imputation leading to the most informative selection of variables. …”

Investigating heterogeneity across autism, ADHD, and typical development using measures of cortical thickness, surface area, cortical/subcortical volume, and structural covariance by Sadat-Nejad, Y, Vandewouw, MM, Cardy, R, Lerch, J, Taylor, MJ, Iaboni, A, Hammill, C, Syed, B, Brian, JA, Kelley, E, Ayub, M, Crosbie, J, Schachar, R, Georgiades, S, Nicolson, R, Anagnostou, E, Kushki, A

“…We integrated cortical thickness, surface area, and cortical/subcortical volume, with a measure of single-participant structural covariance using a graph neural network approach. Results: Our findings suggest two large clusters, which differed in measures of adaptive functioning (χ2 = 7.8, P = 0.004), inattention (χ2 = 11.169, P &lt; 0.001), hyperactivity (χ2 = 18.44, P &lt; 0.001), IQ (χ2 = 9.24, P = 0.002), age (χ2 = 70.87, P &lt; 0.001), and sex (χ2 = 105.6, P &lt; 0.001). …”

Adjustable wind selectivity in shearwaters implies knowledge of the foraging landscape by Harris, S, Bishop, C, Bond, S, Fernandes, P, Guilford, T, Lewin, P, Padget, O, Robins, P, Schneider, W, Waggitt, J, Wilmes, S, Cordes, L

“…Finally, birds are also less wind selective during longer continuous periods of flight, presumably also associated with target-oriented movement. Our findings reveal how an animal’s foraging strategy can dynamically optimize the complex trade-off between efficient travel and accessing known foraging areas, implying the incorporation of prior knowledge of the cost-benefit landscape well beyond the range of what can be detected directly. …”

Territorial movements of African lions: can waterholes shape multiple central-place territories in a savanna ecosystem? by Dejeante, R, Loveridge, A, Macdonald, D, Madlamoto, D, Chamaille-James, S, Valeix, M

“…However, we found that both female and male lions repeatedly moved along straight paths between the waterholes located both in the core and in the periphery of their territories, potentially to defend multiple central-place territories driven by the distribution of waterholes in the landscape. These findings illustrate a case where territorial animals specifically mark feeding sites, increasing the renewal of territorial cues at these key places, potentially using long-distance territorial cues (i.e., vocalizations) to mark uncovered areas, and thereby reducing the cost of patrolling large territories. …”

Multi-mass imaging in chemical reaction dynamics by Kockert, H

“…</p> <p>In Chapter 3, the UV-induced photofragmentation dynamics of the CH₂BrI molecule are studied in a time-resolved UV-pump XUV-probe experiment. While the findings are largely consistent with previous studies on this system, evidence for charge transfer processes between the XUV ionized halogen photoproducts and neutral rotationally excited CH₂Br fragments are found.…”

Water resources and extreme events in the Awash basin: economic effects and policy implications: report prepared for the Global Green Growth Institute by Smale, R, Walker, O, Vadheim, B, Hope, R, Hope, R, Charles, K, Hall, J, Dadson, S, Borgomeo, E, Kebede, S, Alamirew, T, Bekele, F, Mengistu, A, Beyene, S

“…<br> Under current economic conditions, the report finds the consequences of hydrological variability to be severe. …”

On the hidden layer-to-layer topology of the representations of reality realised within neural networks by Gafvert, O, Grindrod, P, Harrington, HA, Higham, CF, Higham, DJ, Yim, KM

“…Instead, the manifold may become folded over and over, filling up further dimensions and creating non-realistic (unforeseeable) proximities.</p> <p><strong>Findings: </strong>We discuss some of the likely consequences of these relatively unforeseen characteristics and, in particular, the possible vulnerability of such algorithms to non-realistic perturbations. …”

Level and association of the general public knowledge and attitude on the role of technology in human trafficking: a quantitative study of Pakistan by Khan, Zeeshan, Mohammad Rahim Kamaluddin, Jamiah Manap, Surendran Rajaratnam, Masnizah Mohd, Chong, Ibrahim Maclean, Ratna Yunita Setiyani, Kalaivanan Syasyila

“…The stakeholders must leverage social media platforms to raise awareness about the ways in which human traffickers exploit technology. The findings of this study are also anticipated to enable the international community to achieve the UN Sustainable Development Goals (SDGs 2030), to focus on this new emerging issue to combat online human trafficking and safeguard the general public.…”
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Fostering motivation in TVET students: the role of learner-paced segments and computational thinking in digital video learning by Wan Nor Ashiqin Wan Ali, Wan Ahmad Jaafar Wan Yahaya, Syed Zulkarnain Syed Idrus, Mohd Noorul Fakhri Yaacob

“…Content delivered in the learner-paced mode allows students to progress through segments at their own pace, while the system-paced mode follows a fixed sequence. The findings from ANOVA analysis revealed that students in the learner-paced mode exhibited significantly higher motivation levels than those in the system-paced mode. …”
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Enhancing ESL low proficiency pre-university students’ writing skills through flipped writing framework by Lee, Rebecca Su Ping, Verezub, Elena, Ida Fatimawati Adi Badiozaman

“…Quantitative analysis yielded two significant findings: firstly, students' writing performance showed a marked improvement from pre-test to post-test when using the flipped classroom model; secondly, a positive correlation emerged between product-genre based flipped learning and writing performance. …”
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News framing of the 2022 Russian-Ukrainian conflict: a comparative analysis of CNN (USA) and CCTV (China) from a war and peace journalism perspective by Wang, Yao, Shahrul Nazmi Sannusi, Shamsiah Abd Kadir

“…Analysing how CNN and CCTV present the conflict from WJ/PJ perspectives helps to facilitate an understanding of how two different media systems might shape their respective audiences’ perceptions according to different ideologies. The findings revealed that CNN mainly focused on “Humanitarian Crisis and Civilian Impacts” and “Military Operations and Strategic”, whereas CCTV predominantly centred on the themes of “Military Operations and Strategic” and “Political Reactions and Stances”. …”
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Types of intermittent fasting and their effects on obesity and type II diabetes mellitus by Shu, Xian Gan, Patricia, Karissa, Yong, Ling Sou, Hui, Ching Low, Teck, Yew Low, Simpson, Timothy, Pei, Paulina Suu Tan, Pey, Yee Lee, Shamsul Mohd Zain, Wickneswari Ratnam

“…Keywords such as “Intermittent fasting”, “Obesity”, “Type II Diabetes Mellitus” were used and relevant articles were selected. The findings of this review showed that intermittent fasting is feasible and effective in reducing body weight and improving blood glucose. …”
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Unveiling the diversity and ecological roles of Macrofungi in Ayer Hitam Forest Reserve, Selangor, Malaysia by Noor Aisyah Mohd Nordin, Nur Ain Izzati Mohd Zainudin, Wan Mohd Syazwan, Nor Azwady Abd Aziz, Mohd Termizi Yusof, Nurul Shazini Ramli

“…Based on species diversity, order Polyporales is the highest occurrence species in the sampling areas with a Shannon-Weiner Index value of 2.103 and Simpson Index value of 0.954, Evenness Index value of 0.601, making it the most abundant order containing Microporus species, The findings are expected to enhance our knowledge of the biodiversity of macrofungi from different substrates in Ayer Hitam Forest Reserve, which can lead to conservation efforts and promote the ecological significance of macrofungi in tropical forest ecosystems.…”
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