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  1. 10161
  2. 10162
  3. 10163
  4. 10164
  5. 10165
  6. 10166

    Developments in THz Polaritonics: Towards Integrated Nonlinear THz Spectroscopy by Sung, Eric Rueyhao

    Published 2024
    “…When optimized, the method generates THz fields with electric field strengths up to 175 kV/cm, which is roughly 20x larger than what is generated by a single line of pump light. …”
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    Thesis
  7. 10167

    Control and operation of modular multilevel converters by Yang, Shunfeng

    Published 2018
    “…The fault tolerant control can be activated with 5ms after the fault occurrence. The MMC is able to seamlessly ride through the switching device open-circuit fault. …”
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    Thesis
  8. 10168

    Simulations study of fluid-structure interaction of a wind turbine by Zheng, Shuai

    Published 2018
    “…This report presents the study of fluid-structure interaction (FSI) of a 5kW horizontal axis wind turbines (HAWT). The motivation of the current investigation is to address the FSI problem of HAWT in the whole flow field analysis with hybrid turbulence model method which is used to find out the flow and structure characteristics of wind turbine in operation under different tip speed ratio (TSR). …”
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    Thesis
  9. 10169

    Effect of educational intervention on the intention to provide family-centered care among selected hospitals’ paediatric nurses in Tehran, Iran by Rostami, Forouzan

    Published 2015
    “…The most significant predictor was attitude (β = 0.393, t =5.914, p < 0.01), followed by perceived behaviour control (β = 0.320, t = 4.815, p < 0.01) and subjective norms (β = 0.172, t = 2.184, p < 0.01). …”
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    Thesis
  10. 10170
  11. 10171

    Surface peptide functionalization of zeolitic imidazolate framework-8 for autonomous homing and enhanced delivery of chemotherapeutic agent to lung tumor cells by Nurul Akmarina, Mohd Abdul Kamal, Emilia, Abdulmalek, Sharida, Fakurazi, Cordova, Kyle E., Mohd Basyaruddin, Abdul Rahman

    Published 2021
    “…Most importantly, this surface-functionalized nanoparticle was more selective towards lung cancer cells (A549) than normal human lung fibroblast cells (MRC-5) with a selectivity index (SI) of 3.98. This work demonstrates a new one-pot strategy for realizing a surface-functionalized zeolitic imidazolate framework that actively targets cancer cells via an autonomous homing peptide system to deliver a chemotherapeutic payload effectively.…”
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    Article
  12. 10172

    Dissolution and biological assessment of cancer-targeting nano-ZIF-8 in zebrafish embryos by Nurul Akmarina, Mohd Abdul Kamal, Emilia, Abdulmalek, Sharida, Fakurazi, Cordova, Kyle E.

    Published 2022
    “…Monitoring malformation showed minimal adverse effects with only 8.3% of edema at 62.5 μg mL–1. This study indicates that cancer-targeting GEM⊂RGD@nZIF, with its pH-responsive behavior for sustaining chemotherapeutic dissolution in a physiologically relevant environment and its non-toxicity toward the healthy embryos within the tested concentrations, has considerable potential for use in cancer treatment.…”
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    Article
  13. 10173

    Integrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture System by Large, Emma, Hughes, David J., Sarkar, Ujjal, Ravindra, Kodihalli C., Young, Carissa L., Rivera-Burgos, Dinelia, Yu, Jiajie, Cirit, Murat, Wishnok, John S, Lauffenburger, Douglas A, Griffith, Linda G, Tannenbaum, Steven R

    Published 2017
    “…Kupffer cell–mediated cytokine release recapitulated an in vivo proinflammatory response exemplified by a cohort of 11 cytokines that were differentially regulated after lipopolysaccharide induction, including interleukin (IL)-1β, IL-1Ra, IL-6, IL-8, IP-10, tumor necrosis factor-α, RANTES (regulated on activation normal T cell expressed and secreted), granulocyte colony-stimulating factor, macrophage colony-stimulating factor, macrophage inflammatory protein-1β, and IL-5. In summary, our findings indicate that three-dimensional liver microphysiological systems may serve as preclinical investigational platforms from the perspective of the discovery of a set of clinically relevant biomarkers including potential reactive metabolites, endogenous bile acids, excreted proteins, and cytokines to predict early drug-induced liver toxicity in humans.…”
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    Article
  14. 10174

    Study of $$ {B}_c^{+}\to {\chi}_c{\pi}^{+} $$ decays by Aaij, R., Abdelmotteleb, A. S. W., Abellan Beteta, C., Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F.

    Published 2024
    “…A study of B c + → χ c π + $$ {B}_c^{+}\to {\chi}_c{\pi}^{+} $$ decays is reported using proton-proton collision data, collected with the LHCb detector at centre-of-mass energies of 7, 8, and 13 TeV, corresponding to an integrated luminosity of 9 fb−1. …”
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    Article
  15. 10175

    State and Dynamics Estimation in an Outdoor Multi-Drone Slung Load System by Merton, Harvey

    Published 2024
    “…Real world testing shows errors of 0.2 m and 5 ◦ respectively. Applying extended Kalman filter and unscented Kalman filter formulations, simulated position estimates average around an error of 0 m, while the error noise magnitude is only 6% of the cable length at 0.06 m. …”
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    Thesis
  16. 10176
  17. 10177

    Cooperation and Fairness in Multi-Agent Reinforcement Learning by Aloor, Jasmine, Nayak, Siddharth Nagar, Dolan, Sydney, Balakrishnan, Hamsa

    Published 2024
    “…For goal coverage scenarios, we find that, on average, the proposed model yields a 14% improvement in efficiency and a 5% improvement in fairness over a baseline model that is trained using random assignments. …”
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    Article
  18. 10178

    An encoding scheme capturing generic priors and properties of amino acids improves protein classification by Zhou, Xinrui, Yin, Rui, Zheng, Jie, Kwoh, Chee-Keong

    Published 2019
    “…Compared with the traditional methods using task-specific designed features, CFreeEnS improves the predicting accuracy, with an increase ranging from 5.54% to 14.14%. The results indicate that the improved CFreeEnS, free from dependence on carefully designed features, is promising in capturing generic priors and essential properties of amino acids, thereby serving as an automated feature engineering method for protein sequences.…”
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    Journal Article
  19. 10179

    Experimental study of single- and two-phase heat transfer of fractal-like structures by Mak, Joel Tse Hoi

    Published 2020
    “…These channels were semi-circular, with a diameter ratio of 2−13, a length ratio of 0.5 and a bifurcation angle of 25˚. A multichannel parallel design consisting of four horizontal channels was used as a comparison. …”
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    Final Year Project (FYP)
  20. 10180

    Scaffold-mediated non-viral delivery platform for CRISPR/Cas9-based genome editing by Chin, Jiah Shin, Chooi, Wai Hon, Wang, Hongxia, Ong, William, Leong, Kam W., Chew, Sing Yian

    Published 2020
    “…To evaluate the genome-editing efficiency of this platform, U2OS.EGFP cells were used as the model cell type. pDOPA coating was essential in allowing Cas9:sgRNA lipofectamine complexes to adhere onto the scaffolds with a higher loading efficiency, while laminin coating was necessary for maintaining cell viability and proliferation on the pDOPA-coated fibers for effective gene editing (21.5% editing efficiency, p < 0.001). Importantly, U2OS.EGFP cells took up Cas9:sgRNA lipofectamine complexes directly from the scaffolds via reverse transfection. …”
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    Journal Article