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721
Smart platform architecture for family of products
Published 2020“…Methods used include product line commonality index, function structure, design structure matrix (DSM), generational variety index (GVI) and system dynamics. …”
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Final Year Project (FYP) -
722
Hydrophosphination as a valuable tool to chiral diphosphines and their derivatives
Published 2022“…Next, the synthesis of C-chiral diphosphines from naturally occurring curcumin and derivatives was attempted and the cytotoxicity of the diphosphine metal complexes was evaluated and compared against cisplatin and curcumin in the MKN74 and MCF7 cancer cell-lines. Lastly, the challenges associated with the generation of chiral phosphine-phosphino-chalcogenide and their complexes were discussed in detail and an example of the catalytic property of the phosphine-phosphino-chalcogenide metal complexes was illustrated.…”
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Thesis-Doctor of Philosophy -
723
Study on supply chain challenges in container shipping : the port operator's perspectice
Published 2009“…Main challenges faced by port operators highlighted in the report include the ever increasing size of vessels, the chronic problem of port congestions and mergers and acquisitions of shipping lines. Some recommendations made for these problems are best practices adopted by ports world wide, while others such as ‘sharing concept’ are derived personally. …”
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Final Year Project (FYP) -
724
Cellular reporter for inflammation.
Published 2011“…Currently, there are commercial green fluorescent protein (GFP) assays available for in vitro cell lines only. There are no in vivo systems that can report NF-B activation in hematopoietic stem cells. …”
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Final Year Project (FYP) -
725
Laser surface treatment of 50CrMo4 steel
Published 2018“…The speed of laser is significance in affecting the width and depth of the laser treated lines. When the speed is too high, the change is not visible, thus, the hardness test cannot be done on the cross section area.…”
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Final Year Project (FYP) -
726
Crypto-linguistics in Singapore : deciphering the Singapore Stone
Published 2019“…The Singapore Stone was a sandstone with around 50 lines of inscription, but was blown up in 1843. A fragment of the original stone now lies in the National Museum of Singapore. …”
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Final Year Project (FYP) -
727
New techniques for automated architectural reconstruction from photographs
Published 2002“…Second, we develop and refine a technique for piecewise planar model fitting involving sweeping polygonal primitives, and assess the performance of this technique. Third, lines at infinity are constructed from image correspondences and used to sweep planes in the principal directions. …”
Conference item -
728
Development of reconstructed intestinal micronucleus cytome (RICyt) assay in 3D human gut model for genotoxicity assessment of orally ingested substances
Published 2022“…Micronucleus assays typically utilise homogenous in vitro cell lines which poorly recapitulate the physiology, biochemistry and genomic events in the gut, the site of first contact for ingested materials. …”
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Journal Article -
729
Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT)
Published 2023“…By performing anti-cancer compound library screen on isogenic cell lines and using extrachromosomal telomeric C-circles, as a bona fide marker of ALT activity, we identify a receptor tyrosine kinase inhibitor ponatinib that deregulates ALT mechanisms, induces telomeric dysfunction, reduced ALT-associated telomere synthesis, and targets, in vivo, ALT-positive cells. …”
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Journal Article -
730
Investigating the content and function of stress-induced extracellular vesicles in colorectal cancer
Published 2021“…Therefore, my DPhil focussed on investigating the potential pro-tumorigenic properties of these “switched” EVs in CRC cell lines in vitro and also assessing the composition of EVs in CRC patient plasma.…”
Thesis -
731
Development of high-affinity peptide-drug conjugates for investigating the TRIM24 PHD and bromodomain
Published 2024“…Although, no significant antiproliferative effects were observed in the ER<sup>+</sup> MCF-7 breast cancer cell line, the triple negative CAL-51 cell line appeared sensitive to simultaneous TRIM24 PHD and BRD inhibition. …”
Thesis -
732
Neuroprotective effect of tocotrienol-rich fraction and a-tocopherol of vitamin E against glutamate toxicity in neuronal cells and astrocytes
Published 2015“…In this study, the effects of vitamin E when supplemented before (pre-treatment) and after (post-treatment) glutamate insult were elucidated in neuronal and astrocyte cell lines. The neuroprotective effect of TRF and α-TCP were investigated. …”
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Thesis -
733
Conformable ultrasound breast patch for deep tissue scanning and imaging
Published 2024“…The in vitro studies and clinical trials reveal that the array using a piezoelectric crystal [Yb/Bi-Pb(In <jats:sub>1</jats:sub> <jats:sub>/2</jats:sub> Nb <jats:sub>1/2</jats:sub> )O <jats:sub>3</jats:sub> -Pb(Mg <jats:sub>1/</jats:sub> <jats:sub>3</jats:sub> Nb <jats:sub>2/3</jats:sub> )O <jats:sub>3</jats:sub> -PbTiO <jats:sub>3</jats:sub> ] (Yb/Bi-PIN-PMN-PT) exhibits a sufficient contrast resolution (~3 dB) and axial/lateral resolutions of 0.25/1.0 mm at 30 mm depth, allowing the observation of small cysts (~0.3 cm) in the breast. …”
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Article -
734
Two-phase immersion cooling for power dense printed circuit board converters
Published 2024“…A theoretical model and numerical solution method for boiling on pin fins is developed and used to design heat spreaders to increase the power dissipation per unit semiconductor area with minimal penalty on the converter volume. …”
Thesis -
735
Serial interconnections of 1-contracting and 2-contracting systems
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Article -
736
Database and Application Programming Interface Development for Rotational Spectroscopy
Published 2024“…A database of spectroscopic data serves as the foundation of the automation pipeline for assigning spectral lines to species. While there are existing databases available for use, we developed our custom database, named SAAGAdb, and an application programming interface (API) to access the database to fulfill the needs of SAAGA. …”
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Thesis -
737
Assessing the financial performance of container shipping companies
Published 2009“…Five companies were shortlisted from the top 30 container shipping lines, where trends and changes in five selected indicators were analyzed over a specified timeframe before and after integration. …”
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Final Year Project (FYP) -
738
Targeted therapy to gastric cancer
Published 2009“…In this study, 17 gastric cancer cell lines were used to screen a library of 60 small molecule inhibitors and chemotherapy drugs for discovery of potential therapeutic agent by methyl thiazole tetrazolium (MTT) assays. 8 effective drugs which include Docetaxel, Paclitaxel, 17-DMAG, Bortezomib, Calyculin A, Okadaic acid, Staurosporine and Bafilomycin A1 were identified and subject to further characterization by IC50 calculation, cell migration assay, morphology study and cell cycle analysis by FACS. …”
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Final Year Project (FYP) -
739
Fullwave modeling of coplanar-waveguide discontinuities for applications in filter design and metamaterial characterization
Published 2008“…Coplanar waveguide (CPW) has been finding wide applications in microwave integrated circuit (MIC) and monolithic microwave integrated circuit (MMIC) due to several advantages it offers over microstrip lines. Typical discontinuities characteristics are an integral part of practical circuit design. …”
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Thesis -
740
Body . space . generative forms.
Published 2011“…The human body and its proportions are often used as blueprint of measurements for constructing regulating lines and division of spaces. As such, the aesthetic and practical relationship between these entities is undisputed. …”
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Final Year Project (FYP)