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4981
Revealing the potential role of hsa-miR-663a in modulating the PI3K-Akt signaling pathway via miRNA microarray in spinal muscular atrophy patient fibroblast-derived iPSCs
Published 2024“…Bioinformatics analysis using various databases was performed to predict the potential putative gene targeted by hsa-miR-663a. The findings showed differential expression of hsa-miR-663a in SMA patients in relation to a healthy control. …”
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4982
Computer aided diagnoses for detecting the severity of Keratoconus
Published 2024“…Conclusion: The algorithm used for extracting the cone base area of the keratoconic cornea at different stages was validated by an ophthalmic specialist to ensure that the cone base area was appropriately extracted. The findings may help ophthalmologists to make informed decisions for patients with severe KC and assessments based on the percentage of corneal defects.…”
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4983
Effect of microwave sintering on density, microstructural and magnetic properties of pure strontium hexaferrite at low temperatures and heating rate
Published 2024“…Coercivity Hc and magnetic energy density BH max recorded optimum values at 1050 °C. The findings emphasize the critical role of microwave sintering in tailoring the properties of strontium hexaferrite for magnetic applications.…”
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4984
Toward low-carbon cities: a review of circular economy integration in urban waste management and its impact on carbon emissions
Published 2024“…We examine city-level CEWM initiatives worldwide, assess the carbon emission quantification methods, and highlight specific CEWM strategies with significant carbon reduction potential. Our findings reveal that city-level initiatives predominantly prioritize waste reduction and prevention (51%), followed by education and engagement (23%), material recycling and upcycling (21%), and waste conversion (6%). …”
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4985
Bacteria as potential biocontrol agents for managing purple witchweed (Striga hermonthica) in grain sorghum
Published 2024“…Additionally, the biopriming with S. morookaensis promoted the growth of shoots and roots of germinating sorghum, regardless of the presence of Striga seeds. These findings highlight the potential of S. morookaensis strain NRRL B-12429 as a viable candidate for biocontrol agent applications in sorghum cultivation. …”
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4986
Restoring restaurant design and layout: towards safer dining out experience
Published 2024“…The interview sessions were recorded and transcribed, whereas the data collected were analyzed using thematic analysis. The findings of this research concluded that the impact of COVID-19 on the restaurants' design and layout were found most in the reduced number of customers, influence on restaurant design and alteration of restaurant layout. …”
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4987
Jaya algorithm hybridized with extreme gradient boosting to predict the corrosion-induced mass loss of agro-waste based monolithic and Ni-reinforced porous alumina
Published 2024“…This study demonstrates the mass loss of monolithic and Ni-reinforced porous alumina developed using rice husk and sugarcane bagasse in acidic and alkaline corrosive media. Based on empirical findings, the formation of a very stable Ni3Al2SiO8 spinelloid phase in the RH-graded composites increased their chemical stability in the corrosive environments compared to their monolithic and corresponding SCB-graded counterparts. …”
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4988
Decoding stakeholder priorities of safety culture preferences in the oil and gas industry
Published 2024“…Management personnel highlighted the importance of safety ownership and communication, whereas policymakers focused on broader, policy-oriented aspects. The findings suggest that safety culture improvement initiatives should be tailored to address the specific needs and priorities of each professional group. …”
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4989
Electron beam grafted Polyethylene/Polypropylene fibers: a novel approach to amine-functionalized adsorbents for Naproxen removal
Published 2024“…Notably, even at a low amine-to-isopropanol ratio (30 %) using EDA, the adsorbents achieved a high naproxen removal rate of 96.90 % within 90 min and an adsorption capacity of 247.10 mg/g, surpassing the performance of the DAP-modified (PE/PP)-g-GMA. These findings suggest that amine-functionalized adsorbents with short alkyl chain lengths exhibit higher removal efficiencies, as they are capable of reducing the residual concentration after adsorption to levels approaching the predicted no-effect concentration.…”
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4990
Mechanical Properties of Biocomposite Films Based Polyvinyl Alcohol/Potato Starch Filled by Coffee Ground Waste
Published 2024“…Fracture morphological analysis via scanning electron microscopy confirmed these findings, revealing wave-like patterns and strong interfacial bonding between the matrix and filler at this concentration. …”
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4991
Work intensity and fat mass percentage are associated with asymptomatic morphometric vertebral fractures in knee osteoarthritis patients: a cross-sectional study
Published 2024“…Multivariable logistic regression analysis revealed that an increase in fat mass percentage resulted in decreased AMVF incidence (HR: 0.83, 95% CI: 0.70–0.97; p = 0.018), while occupation (moderate or heavy work) remained a highly significant predictor (HR: 57.76, 95% CI: 4.23–788.57; p = 0.002). These findings support the potential importance of considering occupational activities and body fat composition in managing AMVF among knee OA patients, but further research is required to establish causal relationships.…”
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4992
Experimental and multiscale analysis of volume fraction effects in tensile properties of recycled PLA-PDA/kenaf fiber 3D printing filament composites
Published 2024“…The methodology integrates experimental single filament tensile testing with multiscale finite element modeling to accurately predict the composite’s mechanical behavior across different scales. The findings reveal that a 5% kenaf fiber weight/volume fraction provides the optimal balance between tensile strength, stiffness, and toughness, achieving a significant 49.3% improvement over the unreinforced rPLA. …”
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4993
Modeling approach of cloud 4D printing service composition optimization based on non-dominated sorting genetic algorithm III
Published 2024“…In this research, the NSGA III algorithm is employed to develop a multiobjective optimization framework for 4D printing service portfolios, addressing critical issues such as service cost, time, quality, adaptability, and overall service optimization amidst fluctuating demand and service availability. The findings indicate that the NSGA III algorithm demonstrates superior performance in terms of generational distance and inverted generational distance, particularly excelling in convergence and diversity for high-dimensional optimization problems when compared to the comparison algorithms. …”
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4994
Sygyzium claviflorum fruit extract preadipocyte differentiation inhibition in 3T3-L1 cells
Published 2024“…Moreover, SCFE suppressed sterol regulatory element binding protein-1 (SREBP-1), peroxisome proliferator-activated receptor-gamma (PPAR-γ), and CCAAT/enhancer-binding protein-alpha (C/EBP-α) gene expressions during preadipocyte differentiation into adipocytes. Conclusion: The findings revealed the anti-adipogenic properties of SCFE, indicating its potential as a natural obesity management remedy. …”
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4995
Mechanical properties of novel hybrid bamboo fibre/ aluminium mesh reinforced polymer composite
Published 2024“…The composites were fabricated using epoxy resin reinforced with bamboo fibre, and an aluminium expanded mesh sheet was constructed using a vacuum infusion process utilising various stacking sequences and mesh sizes. The test findings indicated that the composite material exhibited tensile stress values ranging from 27 to 34 MPa and a corresponding tensile strain value between 1.1% and 1.6%. …”
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4996
Dengue hemorrhagic fever prevention and control: DHF-solve model using linebot-application and GIS
Published 2024“…The factor that most significantly influenced behaviour was people's perception of DHF, which received an average score of 4.19. The findings from the model development indicated that the DHF-Solve Linebot is an effective management and control system for DHF. …”
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4997
RSM and ANN-based optimized ultrasound-assisted extraction of functional components from olive fruit (cv Arbequina): assessment of antioxidant attributes and GC-MS metabolites prof...
Published 2024“…The results of ANN, which employed the multilayer perceptron design, were fairly in line with the findings of the experiments. The antioxidant characteristics and GC-MS metabolite profile of the obtained extracts were examined. …”
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4998
Assessing the sustainability of organic rice farming in Central Java and Jogjakarta: an economic, ecological, and social evaluation
Published 2024“…The results of validation and stability tests indicated that the sustainability model was both stable and reliable across all three dimensions, with an overall sustainability score of 1. These findings underscore the importance of promoting sustainable agricultural practices in organic rice farming and highlight the need for enhanced government involvement in raising awareness, providing training, and fostering educational initiatives to support the economic, ecological, and social dimensions of sustainability in the region.…”
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4999
Aptamer-based detection of foot-and-mouth disease virus using single-stranded DNA probe
Published 2024“…The binding strength analyzed using the equilibrium dissociation constant (Kd) showed strong binding affinity at 3.092 ± 0.05 nM. Based on these findings, the method shows significant potential with high sensitivity and specificity for FMD virus detection assay.…”
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5000
Streamlined boiling lysis DNA extraction for Gram-positive aquaculture pathogen Streptococcus agalactiae
Published 2024“…Extracted DNA was assessed using spectrophotometry, electrophoresis, polymerase chain reaction (PCR) and loop-mediated isothermal amplification (LAMP) while its stability was inspected after five months of storage. The findings revealed variations in DNA yield, purity and integrity among the extraction methods. …”
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