Investigation of compliant fixed abrasive machining of internal surfaces using flexible tool by Vohra Moiz Sabbir

“…Average surface roughness (Ra) value was found to be in the range of 0.8 IJ.m - 1.5 IJ.m depending on tool speed, bend radius of flexible shaft, feed rate, abrasive grain size and the density of abrasive grains on the tool. …”
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Analysis and design of RSSI in the RF receiver chain by Bhaskar Yashaswini

“…The circuit is operated at 1.1V supply voltage and has the maximum power consumption of 330 µW. …”
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The divergent fates of primitive hydrospheric water on Earth and Mars by Wade, Jon, Dyck, Brendan, Palin, Richard M., Moore, James Daniel Paul, Smye, Andrew J.

“…Although some of the water on Mars was lost to space via photolysis following the collapse of the planet’s magnetic field3,4,5, the widespread serpentinization of Martian crust6,7 suggests that metamorphic hydration reactions played a critical part in the sequestration of the crust. …”
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A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein–protein interactions identifies a novel putative Mdm2-binding site in p53 by Wong, Jin Huei, Alfatah, Mohammad, Sin, Mei Fang, Sim, Hong May, Verma, Chandra Shekhar, Lane, David P., Arumugam, Prakash

“…Using the p53-Mdm2 interaction to optimize the assay, we show that the p53-Mdm2 inhibitor nutlin-3 is a substrate for the yeast ATP-binding cassette (ABC) transporter Pdr5. By deleting nine ABC transporter-related genes, we generated a ABC9Δ yeast strain that is highly permeable to small molecules. …”
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Colloidal semiconductor nanocrystals for light-emitting devices : from materials to device perspectives by Shendre, Sushant

“…The novel architecture of this material offers a high level of performance in LED applications to achieve external quantum efficiency (EQE) of 5%, which is among the best achieved by the NPLs to date. …”
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Complexities of the San Andreas fault near San Gorgonio Pass : implications for large earthquakes by Yule, Doug, Sieh, Kerry

“…The pattern of crustal seismicity beneath these structures includes a 5–8 km high east-west striking step in the base of crustal seismicity, which corresponds to the downdip limit of rupture of the 1986 North Palm Springs earthquake. …”
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NALPS : a precisely dated European climate record 120–60 ka by Wang, X., Cheng, Hai, Spötl, C., Edwards, R. Lawrence, Boch, R., Häuselmann, Ph

“…The rapid and large oxygen isotope shifts of 1 to 4.5‰ occurred within decades to centuries and strongly mimic the Greenland D-O pattern. …”
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Let's move with Leon: a qualitative evaluation of a UK digital intervention to improve physical activity in people with a musculoskeletal condition by Webb, Justin, Allison, Heather, Mprah, Michael

“…A total of 128 of the 184 intervention participants (70.11%) provided at least one qualitative comment over the course of the evaluation (mean number of comments per participant = 5); in total, 674 comments were received. The thematic analysis identified three themes: (1) dipping in and out, (2) one size does not fit all and (3) monitoring and feedback. …”
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Determinants of underdiagnosis of COPD in national and international surveys by Lamprecht, B, Soriano, JB, Studnicka, M, Kaiser, B, Vanfleteren, LE, Gnatiuc, L, Burney, P, Miravitlles, M, García-Rio, F, Akbari, K, Ancochea, J, Menezes, AM, Perez-Padilla, R, Montes de Oca, M, Torres-Duque, CA, Caballero, A, González-García, M, Buist, S

“…Only 26.4% reported a previous lung function test, and only 5.0% reported a previous diagnosis of COPD, whereas 9.7% had a postbronchodilator FEV1/FVC < LLN. …”

The relationship between viral clearance rates and disease progression in early symptomatic COVID-19: a systematic review and meta-regression analysis by Singh, S, Boyd, S, Schilling, WHK, Watson, JA, Mukaka, M, White, NJ

“…Treatment benefit was defined clinically as the relative risk of hospitalization/death during follow-up (≥14 days), and virologically as the SARS-CoV-2 viral clearance rate ratio (VCRR). The VCRR is the ratio of viral clearance rates between the intervention and control arms. …”

A comparative analysis of vitrification and two slow freezing methods for gonocyte-containing neonatal calf testicular tissue and subsequent in vitro culture by Tang, S, Jones, C, Davies, J, Lane, S, Coward, K

“…No significant differences were observed in the proportion of seminiferous tubules containing PGP9.5-positive germ cells when compared between the three methods. …”

Role of Tau and NRF2 in oxidative stress responses by Ameyaw, B

“…In the neuroblastoma cell line SH-SY5Y, which expresses high levels of Tau, Tau KO led to increased oxidative stress, reversible by re-expressing Tau, but not fully rescued by NRF2 upregulation or microtubule stabilisation.…”

Relapse after cessation of weekly tocilizumab for giant cell arteritis: a multicentre service evaluation in England by Quick, V, Abusalameh, M, Ahmed, S, Alkoky, H, Bukhari, M, Carter, S, Coath, FL, Davidson, B, Doddamani, P, Dubey, S, Ducker, G, Griffiths, B, Gullick, N, Heaney, J, Holloway, A, Htut, EEP, Hughes, M, Irvine, H, Kinder, A, Kurshid, A, Lim, J, Ludwig, DR, Malik, M, Mercer, L, Mulhearn, B, Nair, JR, Patel, R, Robson, J, Saha, P, Tansley, S, TOC STOP 2022 Investigators, Mackie, SL

“…At time of stopping qwTCZ, median (IQR) prednisolone dose was 2 (0–5) mg/day. By 6, 12 and 24 months after stopping qwTCZ, 21.4%, 35.4% and 48.6%, respectively, had relapsed, requiring an increase in prednisolone dose to a median (IQR) of 20 (10–40) mg/day. 33.6% relapsers had a major relapse as defined by EULAR. …”

Reallocation of time between device-measured movement behaviours and risk of incident cardiovascular disease by Walmsley, R, Chan, S, Smith-Byrne, K, Ramakrishnan, R, Woodward, M, Rahimi, K, Dwyer, T, Bennett, D, Doherty, A

“…For an average individual, reallocating 20 min/day to MVPA from all other behaviours proportionally was associated with 9% (95% CI 7% to 10%) lower risk, while reallocating 1 hour/day to sedentary behaviour from all other behaviours proportionally was associated with 5% (95% CI 3% to 7%) higher risk.</p> <p><strong>Conclusion</strong> Machine-learning methods classified movement behaviours accurately in free-living accelerometer data. …”

‘An unimaginable challenge’: a cross-cultural qualitative study of ethics and decision-making around tracheostomy ventilation in patients with amyotrophic lateral sclerosis by Ozeki-Hayashi, R, Wilkinson, D

“…<p><strong>Methods</strong></p> We conducted semi-structured in-depth interviews with 16 doctors actively involved in the management of ALS patients from Japan (n=7), the UK (n=5), and the US (n=4). We used three hypothetical cases to explore decision-making. …”

Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study by Carter, AR, Gill, D, Davies, NM, Taylor, AE, Tillmann, T, Vaucher, J, Wootton, RE, Munafò, MR, Hemani, G, Malik, R, Seshadri, S, Woo, D, Burgess, S, Davey Smith, G, Holmes, MV, Tzoulaki, I, Howe, LD, Dehghan, A

“…All three risk factors combined were estimated to mediate 42% (36% to 48%) and 36% (5% to 68%) of the effect of education on coronary heart disease in observational and mendelian randomisation analyses, respectively. …”

Jamaican customs data, c. 1800-45 by Graham, A, Lavallee, E

“…Unless otherwise noted, years follow the financial year of the island, running from 30 September to 29 September i.e. "1824/5" refers to the period 30 September 1824 to 29 September 1825.…”

Sudden gains in internet cognitive therapy for social anxiety disorder in routine clinical practice by Yim, SH, Clark, DM, Salkovskis, PM, Thew, GR

“…</p> <p><strong>Conclusions:</strong>&nbsp;Approximately 2 in 5 patients experienced a sudden gain whilst accessing the iCT-SAD intervention in routine practice. …”

Targeting c-Met for endoscopic detection of dysplastic lesions within Barrett’s esophagus using EMI-137 fluorescence imaging by Huang, Y-J, Rieder, J, Tan, KV, Tenditnaya, A, Vojnovic, B, Gorpas, D, Quante, M, Vallis, KA

“…<p>Purpose: Esophageal cancer (EC) carries a poor prognosis with 5-year overall survival of less than 20%. Barrett&rsquo;s esophagus (BE) increases the risk of esophageal adenocarcinoma (EAC). …”

Predictors for severe persisting pain in rheumatoid arthritis are associated with pain origin and appraisal of pain by Baerwald, CG, Stemmler, E, Gnüchtel, S, Jeromin, K, Fritz, B, Bernateck, M, Adolf, D, Taylor, PC, Baron, R

“…</p> <br> <p><strong>Results:</strong> Of 567 patients, 337 (59.4%) were classified as reference group, 102 (18.0%) as nonresponders, and 128 (22.6%) as patients with persisting pain. 21 (8.8%) responders, 28 (35.0%) non-responders, and 27 (26.5%) persisting pain patients tested positive for NeP at week 24. …”