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1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity
Published 2020“…This study aimed to develop selective M. tuberculosis DHFR inhibitors using rationale scaffolding design and synthesis, phenotype-oriented screening, enzymatic inhibitory study, whole cell on-target validation, molecular modeling, and in vitro DMPK determination to derive new anti-TB agents. 2,4-diamino-1-phenyl-1,3,5-triazaspiro[5.5]undeca-2,4-dienes 20b and 20c were identified as selective M. tuberculosis DHFR inhibitors, showing promising antimycobacterial activities (MIC50: 0.01 μM and MIC90: 0.025 μM on M. tuberculosis H37Rv). …”
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Journal Article -
62
A 2'-alkynylnucleotide strategy for site-directed spin labelling of DNA
Published 2016“…The destabilising effect of the spin labelling was determined by UV denaturation studies and circular dichroism, and the spin labelled DNA was investigated by EPR spectroscopy. …”
Thesis -
63
Spin defects in hBN assisted by metallic nanotrenches for quantum sensing
Published 2023“…The negatively charged boron vacancy (VB-) in hBN plays a prominent role, as it can be easily generated while its spin population can be initialized and read out by optical means at room-temperature. …”
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Journal Article -
64
Nonlinear spin filter for non-magnetic materials at zero magnetic field
Published 2021Subjects: Get full text
Journal Article -
65
Three-dimensional photonic topological insulator without spin-orbit coupling
Published 2023“…Spin-orbit coupling, a fundamental mechanism underlying topological insulators, has been introduced to construct the latter's photonic analogs, or photonic topological insulators (PTIs). …”
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Journal Article -
66
Spin-based magnetic random-access memory for high-performance computing
Published 2024“…In contrast to conventional electronic devices, manipulating electric charges in non-magnetic semiconductors to process information, spintronic devices are based on the spin of electrons, offering innovative computing solutions. …”
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Measurement of the Z boson production cross-section in pp collisions at √𝑠 = 5.02 TeV
Published 2024“…</jats:italic>0 <jats:italic>< η <</jats:italic> 4<jats:italic>.</jats:italic>5 with transverse momentum <jats:italic>p</jats:italic><jats:sub>T</jats:sub><jats:italic>></jats:italic> 20 GeV/<jats:italic>c</jats:italic>. …”
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69
Search for Heavy Narrow Dilepton Resonances in Pp Collisions at √s = 7 TeV and √s = 8 TeV
Published 2014“…Data samples from pp collisions at √s = 7 TeV and 8 TeV at the LHC, with integrated luminosities of up to 5.3 and 4.1 fb[superscript −1], respectively, are combined. …”
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70
Phosphatidylinositol 4,5-Bisphosphate Is an HCV NS5A Ligand and Mediates Replication of the Viral Genome
Published 2016“…We investigated interactions between PI(4,5)P2 and hepatitis C virus (HCV) nonstructural protein 5A (NS5A) and effects on the viral life cycle. …”
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Journal Article -
71
Fluctuations of anisotropic flow in Pb+Pb collisions at s NN = 5. 02 TeV with the ATLAS detector
Published 2020“…Multi-particle azimuthal cumulants are measured as a function of centrality and transverse momentum using 470 μb−1 of Pb+Pb collisions at sNN = 5.02 TeV with the ATLAS detector at the LHC. These cumulants provide information on the event-by-event fluctuations of harmonic flow coefficients vn and correlated fluctuations between two harmonics vn and vm. …”
Journal article -
72
5G and Beyond : Fundamentals and Standards /
Published [202Subjects: “…5G mobile communication systems…”
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73
On the intermediate Jacobian of M5-branes
Published 2024“…We study Euclidean M5-branes wrapping vertical divisors in elliptic Calabi-Yau fourfold compactifications of M/F-theory that admit a Sen limit. …”
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74
RISC-V processor FPGA implementation
Published 2024Subjects: Get full text
Final Year Project (FYP) -
75
DSP implementation of V.32 modem
Published 2008“…The project, DSP Implementation of V.32 Modem, is concerned with the implementation of the ITU-T Trellis coding full duplex V.32 modem using a single DSP processor. …”
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Thesis -
76
Analysis of V2X communications
Published 2015“…Therefore to improve our traffic system and improve the fuel consumption efficiency in Singapore, we require a smart technology system: V2X – Talking Car Technology. V2X (aka. C2X) consists of 2 parts: V2V (Vehicle – to – Vehicle) and also V2I (Vehicle – to – Infrastructure). …”
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Final Year Project (FYP) -
77
Broadcasting in Asia : twenty-five years from now
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Measurements of the azimuthal anisotropy of prompt and nonprompt charmonia in PbPb collisions at √𝑠NN = 5.02 TeV
Published 2023“…Abstract The second-order (v2) and third-order (v3) Fourier coefficients describing the azimuthal anisotropy of prompt and nonprompt (from b-hadron decays) J/ψ, as well as prompt ψ(2S) mesons are measured in lead-lead collisions at a center-of-mass energy per nucleon pair of s NN $$ \sqrt{s_{\textrm{NN}}} $$ = 5.02 TeV. …”
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