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  1. 201

    Determination of the life span of inflammatory dendritic cells by Tay, Yong Long

    Published 2014
    “…More importantly, we demonstrated the presence of Plet-1+ DCs in brain of P.berghei infected mice which open up a new disease model for the characterization of Plet-1+ DCs. In conclusion, our findings on the turnover rate of Plet-1+ DC can be used in future studies to maintain the ablation of this population for its characterization during steady state and DSS-induced inflammation.…”
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    Final Year Project (FYP)
  2. 202

    Development of immune-modulatory RNAS to regulate RIG-I-like receptors mediated antiviral immune response for therapy and vaccination by Yong, Hui Yee

    Published 2019
    “…From these hairpin dsRNAs, the shortest hairpin required to activate type I interferon signalling is the RNA with 10 perfectly base paired stem RNA (3p10L). From these findings, mismatch along the stem of the RNA was introduced to create a guanosine insertion along the stem of the 3p10L RNA and enhanced type I interferon signalling in both HEK-Lucia™ RIG-I cells and THP1-Dual™ with the guanosine insertion at the position 9 of 3p10L (3p10LG9) were observed. …”
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    Thesis
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    Cable health degradation IV by Ching, Chee Yong

    Published 2022
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    Final Year Project (FYP)
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