Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging by Baik, Sang-Ha, Selvaraji, Sharmelee, Fann, David Y., Poh, Luting, Jo, Dong-Gyu, Herr, Deron R., Zhang, Shenpeng R., Kim, Hyun Ah, Silva, Michael De, Lai, Mitchell K. P., Chen, Christopher Li- Hsian, Drummond, Grant R., Lim, Kah-Leong, Sobey, Christopher G., Arumugam, Thiruma V.

“…Our data provide a genetic-based molecular framework for hypoperfusion-induced hippocampal damage and reveal common cellular signaling pathways likely to be important in the pathophysiology of VaD.…”
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Metrics to relate COVID-19 wastewater data to clinical testing dynamics by Xiao, Amy, Wu, Fuqing, Bushman, Mary, Zhang, Jianbo, Imakaev, Maxim, Chai, Peter R., Duvallet, Claire, Endo, Noriko, Erickson, Timothy B., Armas, Federica, Arnold, Brian, Chen, Hongjie, Chandra, Franciscus, Ghaeli, Newsha, Gu, Xiaoqiong, Hanage, William P., Lee, Wei Lin, Matus, Mariana, McElroy, Kyle A., Moniz, Katya, Rhode, Steven F., Thompson, Janelle, Alm, Eric J.

“…Time lag and transfer function analysis showed that wastewater data preceded clinically reported cases in the first wave of the pandemic but did not serve as a leading indicator in the second wave, likely due to increased testing capacity, which allows for more timely case detection and reporting. …”
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Host genotype and microbiome associations in co-occurring clonal and non-clonal kelp, Ecklonia radiata by Gonzalez, Sebastian Vadillo, Vranken, Sofie, Coleman, Melinda A., Wernberg, Thomas, Steinberg, Peter D., Marzinelli, Ezequiel Miguel

“…Thus, factors regulated by the host genotype (e.g. secondary metabolite production) likely drive differences in microbial communities between morphs. …”
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A comparative analysis of ENCODE and Cistrome in the context of TF binding signal by Perna, Stefano, Pinoli, Pietro, Ceri, Stefano, Wong, Limsoon

“…Results: We provide evidence that data points with high signalValue(s) (top 25% of values) are more likely to be consistent between ENCODE and Cistrome in human cell lines K562, GM12878, and HepG2. …”
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Factors associated with the intention to practise family planning among antenatal women with risk of gestational diabetes mellitus in Klang Health District: a cross-sectional study by Baharuddin, Siti Athirah, Sumsusdin, Mohd Hafiz, Dong, Ley Na, Lim, Pei Sean, Hameed, Nasrinsa Shahul, Md Nawawi, Nor Aliah, Affan, Nur Akmal, Kanapathy, Shanmuga Kritika, Mohamad, Fadzilah, Cheong, Ai Theng

“…Malay antenatal women from low-income households with good knowledge and previous practice were more likely to have the intention to practise FP after delivery. …”
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Plan Implementation Challenges in a Shrinking City: A Conformance Evaluation of Youngstown’s (OH) Comprehensive Plan With a Subsequent Zoning Code by Ryan, Brent D., Gao, Shuqi

“…Takeaway for practice: Our findings indicate that implementing smart shrinkage land use recommendations in shrinking cities is likely to be challenging because legislators may resist codification of reduced populations and lessened economic capacity. …”
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A Wavelet-Based Approach Reveals Host-Cell-Type-Specific Multi-omics Networks in Inflammatory Bowel Disease by Chang, Stephanie, Shankar, Adeethyia, Zhao, Yongzhong, Liu, Tong, Wang, Xiaodi

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The Origins of the East Greenland Coastal Current on the Northeast Greenland Shelf: a Comparison of Two Reanalysis Products by Vianco, Sara L.

“…The EGCC in RARE is primarily buoyancy-driven, though the along-coast winds likely play a major role in maintaining the density front that supports the EGCC. …”
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Carbon Capture Efficiency in Natural Gas Combined Cycle Power Plants: Analyzing the Effects of Variable Load Operations by Knight, Caleb M.

“…Harsher start-up penalties applied to natural gas plants likely increase the incremental value of alternative energy technologies, although natural gas retains a critical role in the energy mix.…”
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Are there advantages to believing in fate? the belief in negotiating with fate when faced with constraints by Au, Evelyn W. M., Savani, Krishna

“…Instead, when individuals face constraining circumstances in which potential courses of actions are clearly limited, they are more likely to believe that they are able to negotiate with fate, and this belief can help them move forward from negative outcomes. …”
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Geographically-aware mobile application for managing events and interest group communications by Lee, Chong Yan

“…The proliferation of social media platforms, such as Instagram, Facebook, Twitter and Reddit, is attributed to humans’ need for more information to make more informed decision or to simply get together to fish out common gossips within the communities, with the likes of Reddit and Twitter. However, sometimes, people need timely information to make time-critical decision. …”
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On-chain analysis and cryptocurrency price forecasting using on-chain metrics by Sharma, Akshat

“…As blockchain technology continues to evolve, it is likely that the use cases for cryptocurrencies will expand, and the demand for these digital assets will continue to grow. …”
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Investigation of the fuel consumption of a ship considering the dynamic coupling effect among resistance, propeller torque and engine power under the control of a governor by Beh, Gerald Kah Hooi

“…Given the extensive costs involved to upgrade an existing ship in the fleet, it is likely that most ship owners will choose to reduce their ships’ speed. …”
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Molecular and biochemical characterisation of human casein kinase I alpha splice variants by Yong, Thomas Joon Kin.

“…Both splice variants are also likely to be encoded by the 2.4 kb mRNA transcripts, generated by employing an alternate polyadenylation signal identified in the longer transcripts. …”
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Advanced nanostructured materials : wide-band-gap oxides based magnetic semiconductors by Xing, Guozhong

“…Semiconductor spintronics has already become a major research area. Spintronics is very likely to have a significant impact on future generations of devices.Operation of spintronic devices could consume much less energy because aligning spins is more efficient than redistributing charges. …”
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The inhibitory effect of medication on the anaerobic co-digestion of food waste and brown water by Ng, Si Jia.

“…The inhibition level of both medications is likely to lie between 1mM and 10mM. It was observed that when paracetamol presented at concentration no more than 1mM, there was no significant impact on the biogas production. …”
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Development of novel monitors for early detection of fouling in reverse osmosis systems by Sim, Victor Siang Tze

“…The current generation of RO membranes is of sufficiently high permeability that further significant improvement in RO membrane permeability is less likely to be the primary driver for a major reduction in the cost of desalination but should arise from a variety of other process improvements. …”
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Time to resolution and effect on quality of life of molluscum contagiosum in children in the UK: a prospective community cohort study by Olsen, JR, Gallacher, J, Finlay, AY, Piguet, V, Francis, NA

“…</p> <p><strong>Interpretation</strong> One in ten children with molluscum contagiosum is likely to have a substantial effect on their quality of life and therefore treatment should be considered for some children, especially those with many lesions or who have been identified as having a severe effect on quality of life. …”

Molluscum contagiosum and associations with atopic eczema in children: a retrospective longitudinal study in primary care by Olsen, JR, Piguet, V, Gallacher, J, Francis, NA

“…Children were found to be more likely to have an MC consultation if they had previously consulted a GP with AE (OR 1.13; 95% CI = 1.11 to 1.16; P<0.005).…”

Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial by McIlroy, G, Gaskell, C, Jackson, A, Yafai, E, Tasker, R, Thomas, C, Fox, S, Boucher, R, Ghebretinsea, F, Harrison, C, Mead, AJ, McMullin, MF

“…It has shown activity in MF and is well-tolerated, but combination with other therapies is likely needed to achieve clonal remission. Combining a JAK2 inhibitor with an interferon may be synergistic, as haematopoietic cells are activated from quiescence (a typical kinase resistance mechanism) rendering them more sensitive to inhibition. …”