A novel human stem cell platform for probing adrenoceptor signaling in iPSC derived cardiomyocytes including those with an adult atrial phenotype by Ahmad, F

“…</p> <p>Drug targeting of atrial-specific ion channels has been difficult because of lack of availability of appropriate cardiac cells, and preclinical testing studies have been carried out in non-cardiac cell lines, heterogeneous cardiac populations or animal models that have been unable to accurately represent human cardiomyocyte physiology. …”

An aerodynamic investigation of a high-pressure turbine using rotor casing static pressure measurements at engine representative conditions with different tip designs, tip gaps and... by Singh, D, Beard, PF, Cardwell, D, Staelens, V, Bahulekar, P, Stokes, M, Bather, S, Chana, KS

“…Steady and unsteady casing static pressure measurements were acquired, using pneumatic lines and high-frequency response (∼100 kHz) Kulite pressure transducers respectively. …”

Inflammation and colorectal cancer: elucidation of the cellular and molecular mechanisms by which interleukin 22 contributes to the development and progression of colorectal cancer by McCuaig, S

“…Using a panel of CRC cell lines and primary human organoids, we confirmed that this prognostic association is due to a functional interaction between IL-22 and mutant KRAS by observing that IL-22 enhances chemoresistance, 3-dimensional clonogenicity, and proliferation specifically in CRC cells with both high IL-22 receptor levels and <em>KRAS</em> mutations. …”

Citizenship and the politics of poverty definition during the segregation, apartheid and democratic eras in South Africa: 1910-2010 by Magasela, W

“…The Household Subsistence Level (HSL) and the Minimum Living Level (MLL) were derivatives of the PDL (the HSL was exactly the PDL, the MLL was lower in value) and were conceptually similar were used as poverty definitions and poverty lines to fix the wages of black workers, thus showing the link between the denial of citizenship and the politics of poverty definition.…”

Assessing the kinetics of oxygen-unloading from red cells using FlowScore, a flow-cytometric proxy of the functional quality of blood by Rabcuka, J, Smethurst, P, Dammert, K, Saker, J, Aran, G, Walsh, G, Tan, J, Codinach, M, McTaggart, K, Marks, D, Bakker, S, McMahon, A, Di Angelantonio, E, Roberts, D, Blonski, S, Korczyk, P, Shirakami, A, Cardigan, R, Swietach, P

“…Applying FlowScore to data from the COMPARE study revealed a positive association with the time-delay from sample collection to measurement, which was verified experimentally. The LifeLines dataset revealed age, sex, and smoking among factors affecting FlowScore. …”

Dress, Feminism, and British New Woman Novels by Allen-Johnstone, C

“…For example, Grand elevated cross-class feminism, but she belittled middle-class women's taste, side-lined poor women’s most pressing sartorial concerns, and dressed to impress. …”

The impact of the World Wide Web on public relations agencies in Singapore. by Wong, Voal Voal., Seah, Sandra Meow Khim.

“…The researchers explore the potential of the WWW as a PR tool, the history of the Internet and its likely developments in the near future to better understand the impact of this new medium. …”
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Development of the capital market in Malaysia : a critical analysis by Li Qingyuan, Lim Boon Hau, Teo Yong Meng

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Demonstratives in Singapore Malay : expression of stance through the use of Itu and Ini by Soffia Ghazali

“…In the case of multiple demonstratives, one of the demonstratives is likely to carry out the tracking or pointing function, making the other demonstrative available to express other information such as stance.…”
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Automatic retrieval of visual continuity errors in movies by Pickup, L, Zisserman, A

“…In this work we develop a scheme for automatically detecting these errors and producing a ranked list of the most likely inconsistencies, working from a commercial DVD release. …”

Purging to transform the post-colonial state: evidence from the 1952 Egyptian Revolution by Ketchley, N, Wenig, G

“…Experienced bureaucrats and those with university education were more likely to be retained. This threat-competence calculation also informed which ministries experienced more purging. …”

Paraneoplastic neurological syndromes: a practical approach to diagnosis and management by Binks, S, Uy, C, Honnorat, J, Irani, SR

“…The pathogenic mediators are likely to be neuronal-specific T cells. There is a variable response to immunotherapies and the clinical syndrome helps to direct the search for a specific set of tumours. …”

An undue emphasis on rural older adults in the Chief Medical Officer's annual report 2023? by Cheetham, NJ, Dhesi, J, Hopper, A, Dowd, JB, Steves, CJ

“…Older adults in urban areas are much more likely to live in deprived areas than older adults in rural areas. …”

Near-term deployment of novel carbon removal to facilitate longer-term deployment by Nemet, GF, Gidden, MJ, Greene, J, Roberts, C, Lamb, WF, Minx, JC, Smith, SM, Geden, O, Riahi, K

“…This commentary shows that the deployment of novel CO₂&nbsp;removal (CDR) over the next decade, its formative phase, is likely to be consequential in determining whether CDR will be available at scale and in time to reach net-zero CO₂&nbsp;emissions consistent with the Paris Agreement&rsquo;s temperature goal.…”

Perceptions of impure innovation: health professionals’ experiences and management of stigmatization when working as digital innovators by Gill, MJ, Naughton, B, Field, M, Shaw, S

“…We theorize that the more central a dual-role professional is within an organization and the more their innovation deviates from standard professional duties, the more likely the innovation is to be viewed as impure within a professional group and be the target of stigmatization. …”

Promoting strategic internal communication in governance to enhance employee creativity in organization by Nur Hidayah, Shamsul Azhar, Fadzida, Ismail, Noor Akma, Abu Bakar

“…The results indicate that when internal communication and leadership communication in governance are symmetrical, individuals are more likely to receive feedback from a variety of interpersonal sources, including supervisors, colleagues, and peers from different departments. …”
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Modelling the impact of testing, contact tracing and household quarantine on second waves of COVID-19 by Aleta, Alberto, Martín-Corral, David, Pastore y Piontti, Ana, Ajelli, Marco, Litvinova, Maria, Chinazzi, Matteo, Dean, Natalie E., Halloran, M. Elizabeth, Longini Jr, Ira M., Merler, Stefano, Pentland, Alex, Vespignani, Alessandro, Moro, Esteban, Moreno, Yamir

“…While severe social-distancing measures have proven effective in slowing the coronavirus disease 2019 (COVID-19) pandemic, second-wave scenarios are likely to emerge as restrictions are lifted. Here we integrate anonymized, geolocalized mobility data with census and demographic data to build a detailed agent-based model of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in the Boston metropolitan area. …”
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Two Paths: Why States Join or Avoid China’s Belt and Road Initiative by Atkins, Eleanor, Fravel, M Taylor, Wang, Raymond, Ackert, Nick, Huang, Sihao

“…We hypothesize, and find support for, the argument that democracies are less likely to join because they view participating in a Chinese-led initiative as more costly than non-democracies. …”
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A modified viscous flow law for natural glacier ice: Scaling from laboratories to ice sheets by Ranganathan, Meghana, Minchew, Brent

“…Our results yield a map of the dominant deformation mechanisms in the Antarctic Ice Sheet, showing that, contrary to long-standing assumptions, dislocation creep, characterized by a value of the stress exponent, likely dominates in all fast-flowing areas. This increase from the canonical value of dramatically alters the climate conditions under which marine ice sheets may become unstable and drive rapid rates of sea-level rise.…”
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The potential of smartphone apps in informing protobacco and antitobacco messaging efforts among underserved communities : longitudinal observational study by Lee, Edmund Wei Jian, Bekalu, Mesfin Awoke, McCloud, Rachel, Vallone, Donna, Arya, Monisha, Osgood, Nathaniel, Li, Xiaoyan, Minsky, Sara, Viswanath, Kasisomayajula

“…Health apps could be used to assess individual-level exposure to tobacco marketing, particularly in relation to the locations of TROs as well as locations where they were most likely to smoke. To date, it remains unclear how health apps could be used practically by health promotion organizations to better reach underserved communities in their tobacco control efforts.…”
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