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5221
The relationship between leisure time physical activity patterns, Alzheimer’s disease markers and cognition
Published 2025“…Engagement in leisure time physical activity in the life course is associated with better cognitive functioning at age 70, even in those with early markers of Alzheimer’s disease. If causal, this is likely via multiple pathways, potentially through the preservation of hippocampal volume, as well as via cognitive resilience pathways delaying cognitive manifestations of early markers of Alzheimer’s disease, particularly in women. …”
Journal article -
5222
Adverse health events associated with antipsychotic use: an umbrella review
Published 2021“…In terms of patient variables, older adults aged over 65 and patients with dementia were more likely to experience antipsychotic-associated adverse outcomes than adults and patients with schizophrenia. …”
Thesis -
5223
Discrete differential geometry driven methods for architectural geometry
Published 2022“…This enables easy integration of existing and future 3D editing techniques with rich data models. The method links the original data model to the edited geometry using point set registration, recovering the existing information based on spatial and UV search methods, and automatically labels the newly created geometry. …”
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Thesis-Doctor of Philosophy -
5224
霸凌小说的翻译研究 —— 以 Thirteen Reasons Why 和《汉娜的遗言》为例来探讨译本如何再现原著的主题思想 = A translation study on novels about bullying – using Thirteen Reasons Why and its Taiwan version to explore how the...
Published 2022“…The literary translation of bullying themed novels is closely linked with the current state of our community, which gives it value and importance. …”
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Final Year Project (FYP) -
5225
Innovation and firm survival: the role of timing, funding, and networks
Published 2024“…There is a large body of literature that provides empirical evidence for the debate regarding the positive and negative links between firms’ innovation and survival. While many studies have discussed how innovation influences firms’ survival, little has been done to explore how this relationship is shaped by other factors. …”
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Thesis-Doctor of Philosophy -
5226
Investigating viral glycosylation pathways for drug and vaccine development
Published 2021“…Iminosugars, which inhibit N-linked glycan processing enzymes such as endoplasmic reticulum alpha-glucosidase I and II of the glycoprotein quality control pathway, constituted one of the two most promising groups of drugs in this antiviral cellular screen that have not entered clinical trials yet.…”
Thesis -
5227
Topochemical manipulation of some complex transition metal oxides
Published 2016“…This phase is composed of sheets of apex-linked Ni<sup>1+</sup>O<sub>4</sub> and Ru<sup>2+</sup>O<sub>4</sub> squares in a checkerboard ordered arrangement. …”
Thesis -
5228
Differences in the effectiveness of individual-level smoking cessation interventions by socioeconomic status
Published 2025“…<p><b>Background</b></p> People from lower socioeconomic groups are more likely to smoke and less likely to succeed in achieving abstinence, making tobacco smoking a leading driver of health inequalities. …”
Journal article -
5229
Early Immune Regulatory Changes in a Primary Controlled Human Plasmodium vivax Infection: CD1c + Myeloid Dendritic Cell Maturation Arrest,...
Published 2017“…Induction of the kynurenine pathway and increased Treg activation, together with skewed mDC maturation, suggest P. vivax promotes an immunosuppressive environment, likely impairing the development of a protective host immune response.…”
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Journal Article -
5230
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5231
Selective lighting up of epiberberine alkaloid fluorescence by fluorophore-switching aptamer and stoichiometric targeting of human telomeric DNA G-quadruplex multimer
Published 2015“…The steady-state absorption, steady-state/time-resolved fluorescence, and NMR studies demonstrate that EPI most likely interact with the 5′ end flanking sequence substructure beyond the core [Q] and the G-quadruplex tetrad in a much more specific manner than the other alkaloids. …”
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Journal Article -
5232
Structural analysis of the novel influenza A (H7N9) viral Neuraminidase interactions with current approved neuraminidase inhibitors Oseltamivir, Zanamivir, and Peramivir in the pre...
Published 2013“…Results: Combination of molecular docking and Molecular Dynamics simulation reveal that zanamivir forms more favorable and stable complex than oseltamivir and peramivir when binding to the active site of the H7N9 neuraminidase. And it is likely that the novel influenza A (H7N9) virus adopts a higher probability to acquire resistance to peramivir than the other two inhibitors. …”
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Journal Article -
5233
Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology
Published 2025“…In other words, analyses with results that were far from the mean were no more or less likely to have dissimilar variable sets, use random effects in their models, or receive poor peer reviews than those analyses that found results that were close to the mean. …”
Journal article -
5234
Fiona Patrick - Thesis submitted in partial fulfilment of the degree of Doctor of Clinical Psychology (DClinPsych)
Published 2024“…Self-loathing may be a relevant NSB in overweight/obese populations. Considering the likely heterogeneity of overweight/obese populations is important in future work.…”
Thesis -
5235
Forwards in time approaches to understanding genealogies in Λ-Fleming-Viot type models
Published 2024“…The patterns of isolation by distance reveal that ancestors are more likely to have originated from areas of high population density. …”
Thesis -
5236
Understanding customer retrials in call centers: preferences for service quality and service speed
Published 2021“…<p><strong>Problem definition: </p></strong> Customers are likely to initiate retrial calls when their previous contact with a call center fails to deliver a satisfactory resolution. …”
Journal article -
5237
Integrated transcriptomic and proteomic profiling of responses to clinical and novel bisphosphonates
Published 2024“…Pre-clinical studies also indicate that the observed non-skeletal effects of bisphosphonates are likely due to mechanisms beyond inhibition of osteoclasts. …”
Thesis -
5238
Long Covid: a global health issue – a prospective, cohort study set in four continents
Published 2024“…Participants in HICs were more likely to report not feeling fully recovered (54.3% vs 18.0%, p<0.001; 56.8% vs 40.1%, p<0.001), fatigue (42.9% vs 27.9%, p<0.001; 41.6% vs 27.9%, p<0.001), new/persistent fever (19.6% vs 2.1%, p<0.001; 20.3% vs 2.0%, p<0.001) and have a higher prevalence of anxiety/depression and impact on usual activities compared with participants in LMICs at 2 to <6 and 6 to <12 months post-COVID-19 hospital discharge, respectively. …”
Journal article -
5239
Consensus on current management of endometriosis
Published 2013“…A different group of international experts from those participating in this process would likely have yielded subtly different consensus statements. …”
Journal article -
5240
Internet tool to support self-assessment and self-swabbing of sore throat: development and feasibility study
Published 2023“…A web-based tool that helps people assess their sore throat, through the use of clinical prediction rules, taking throat swabs or saliva samples, and taking throat photographs, has the potential to improve self-management and help identify those who are the most and least likely to benefit from antibiotics. <br><strong> Objective:<br></strong> We aimed to develop a web-based tool to help patients and parents or carers self-assess sore throat symptoms and take throat photographs, swabs, and saliva samples for diagnostic testing. …”
Journal article