Selective targeting of MYC mRNA by stabilized antisense oligonucleotides by Gill, Taylor, Wang, Haichuan, Bandaru, Raj, Lawlor, Matthew, Lu, Chenyue, Nieman, Linda T, Tao, Junyan, Zhang, Yixian, Anderson, Daniel G, Ting, David T, Chen, Xin, Bradner, James E, Ott, Christopher J

“…MYCASO treatment of cancer cell lines leads to significant inhibition of cellular proliferation while specifically perturbing MYC-driven gene expression signatures. …”
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Unsupervised Learning for Generative Scene Editing and Motion by Fang, David S.

“…In this thesis, we propose two distinct lines of unsupervised learning work with generative applications: 1) BlobGSN and 2) optical flow estimation and flow generation with diffusion models. …”
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Analysis of subtelomeric virulence gene families in Plasmodium falciparum by comparative transcriptional profiling by Witmer, Kathrin, Schmid, Christoph D., Brancucci, Nicolas M. B., Luah, Yen-Hoon, Preiser, Peter Rainer, Bozdech, Zbynek, Voss, Till S.

“…Here, we analysed promoters of upsA, upsB and upsC var, rifA1-type rif, stevor, phist and pfmc-2tm genes and investigated their role in endogenous gene transcription by comparative genome-wide expression profiling of transgenic parasite lines. We find that the three major var promoter types are functionally equal and play an essential role in singular gene choice. …”
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A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system by Shen, Yunbing, Jiang, Long, Iyer, Vaishnavi Srinivasan, Raposo, Bruno, Dubnovitsky, Anatoly, Boddul, Sanjaykumar V., Kasza, Zsolt, Wermeling, Fredrik

“…Here, we present a rapid and universal experimental approach to functionally analyze a CRISPR-targeted cell population that does not involve generating clonal lines. As a simple readout, we leverage the CRISPR-induced genetic heterogeneity and use sequencing to identify how different genotypes are enriched or depleted in relation to the studied cellular behavior or phenotype. …”
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Elucidating the size-dependency of in vitro digested polystyrene microplastics on human intestinal cells health and function by Ma, Yiyuan, Koh, Cheryl Jie Yan, Lim, Hong Kit, Shi, Pujiang, Tay, Chor Yong

“…Herein, the potential deleterious biological effects of pristine and in vitro digested polystyrene (PS) MPs of varying sizes (i.e., 0.1, 1, and 10 µm) are systematically examined over a wide concentration range of 25–400 µg mL−1 on two human intestinal cell lines, namely Caco-2 and NCM 460. Specifically, significant internalization of 0.1 and 1 µm PS -MPs have been observed in both cell types 24 h postexposure. …”
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Label-free assessment of differentiation efficiency in iPSC-derived spinal cord progenitor cells via Magnetic Resonance Relaxometry (MRR) by Tan, Jerome Zu Yao, Chen, Jiahui, Roxby, Daniel, Chooi, Wai Hon, Nguyen, Tan Dai, Ng, Shi-Yan, Chew, Sing Yian, Han, Jongyoon

“…In this study, human iPSCs derived from Cord Lining Endothelial cells were differentiated into Spinal-cord Progenitor Cells (SCPCs) through a 10-day process. …”
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Flexible integrated sensor with asymmetric structure for simultaneously 3D tactile and thermal sensing by Wang, Yongqing, Sun, Kun, Zhang, Qisheng, Yu, Samson Shenglong, Han, Boon Siew, Wang, Jianpeng, Zhao, Mingyan, Meng, Xianglin, Chen, Sicheng, Zheng, Yuanjin

“…The resistive thermal sensors are fabricated with serpentine lines and possess stable heat-sensing performance (165 mV/°C) under shape deformation conditions. …”
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Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin by Peng, Minhua, Watanabe, Satoru, Chan, Kitti Wing Ki, He, Qiuyan, Zhao, Ya, Zhang, Zhongde, Lai, Xiaoping, Luo, Dahai, Vasudevan, Subhash G., Li, Geng

“…In addition, ADE-mediated dengue virus infection of human cell lines and primary PBMCs was inhibited. In a time-of-drug-addition study, luteolin was found to reduce infectious virus particle formation, but not viral RNA synthesis, in Huh-7 cells. …”
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Mythical heroines : the appropriation of myth in reconstructing female identities in ethnic American literature by Goh, I-Mei.

“…The three literary texts being investigated along these lines are Maxine Hong Kingston’s The Woman Warrior, Bharati Mukherjee’s Jasmine and Toni Morrison’s Beloved. …”
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Functional analysis of root-preferential oil palm metallothionein promoter in tobacco by Masura, Subhi Siti, Shaharuddin, Noor Azmi, Masani, Mat Yunus Abdul, Chan, Kuang-Lim, Low, Eng-Ti Leslie, Chan, Pek-Lan, Rahmah, Abdul Rahman Siti, Amiruddin, Nadzirah, Abdullah, Mohd Puad, Azzeme, Azzreena Mohamad, Parveez, Ghulam Kadir Ahmad, Abd Rasid, Omar

“…Stable functional characterisation of tobacco transgenic lines using the T1 generation showed that a deletion construct, designated as RSP-2D (1107 bp), directed strong GUS expression at all stages of root development, particularly in mature roots. …”

Determinants of Expatriate Manager Failures in the International Assignment by Mansor, Mohd Fitri, Abd Hamid, Nurzawani, Kamil, Syahida, Abu, Noor Hidayah

“…The international assignment requires an organization send their staff abroad for high potential career development, to coordinate global lines of business, transfer the organization knowledge in abroad, expand into new markets worldwide and also manage an international subsidiary. …”
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Global research trend of sustainable transport in response to energy efficiency: A bibliometric analysis by Maryam Jamilah, Asha’ari, Salina, Daud, Kasavan, Saraswathy, Wan Mohammad Taufik, Wan Abdullah, Siti Indati, Mustapa, Rajadurai, Jegatheesan, Nurul Nadiah, Ahmad, Wan Noordiana, Wan Hanafi, Siti Norhidayah, Toolib, Mohamed Azrin, Mohamed Ali

“…The study found that the subject categories of ‘‘transport planning,’’ ‘‘transport policy,’’ ‘‘climate change,’’ ‘‘electric vehicles,’’ and ‘‘public transport’’ are the most prolific research contributors. …”
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Demographic differences in International students' information source uses and everyday information seeking challenges by Sin, Sei-Ching Joanna

“…However, their everyday life information seeking (ELIS) behavior is seldom studied. This hinders the planning of information services and information literacy training. …”
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Invited perspectives : how machine learning will change flood risk and impact assessment by Wagenaar, Dennis, Curran, Alex, Balbi, Mariano, Bhardwaj, Alok, Soden, Robert, Hartato, Emir, Mestav Sarica, Gizem, Ruangpan, Laddaporn, Molinario, Giuseppe, Lallemant, David

“…Flood risk and impact assessments are also being influenced by this trend, particularly in areas such as the development of mitigation measures, emergency response preparation and flood recovery planning. Machine learning methods have the potential to improve accuracy as well as reduce calculating time and model development cost. …”
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Stochastic optimization model for water allocation on a watershed scale considering wetland’s ecological water requirement by Xu, Ye, Wang, Yu, Li, Sha, Huang, Guohe, Dai, Chao

“…LBNSCCP model) was proposed for supporting the water supply planning and wetland restoration activities of the Xiaoqing River watershed. …”
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Electricity load forecasting for smart home by Lin, James Rizhong

“…Electricity load forecasting (ELF) is a significant activity in topics such as power systems planning & operation. With the adoption of clean and sustainable energy, together with the need for more efficient and reliable power grids, there is a push towards Smart Grid. …”
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Autonomous navigation system by Au, Yi Xian

“…We suggest a multi-robot global planning pipeline that is hierarchical that prioritizes the agents to prevent collisions between them and compute their trajectories toward the specified target. …”
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Unsupervised land-use change detection using multi-temporal POI embedding by Yao, Yao, Zhu, Qia, Guo, Zijin, Huang, Weiming, Zhang, Yatao, Yan, Xiaoqin, Dong, Anning, Jiang, Zhangwei, Liu, Hong, Guan, Qingfeng

“…Rapid land-use change detection (LUCD) is pivotal for refined urban planning and management. In this paper, we investigate LUCD through learning embeddings of points of interest (POIs) from multiple temporalities. …”
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Vinyl sulfone functionalized injectable thermogels for facile peptide coupling by Oei, John Xin Jian

“…Future studies, such as bioactive peptide functionalization and formation of a strong crosslinked gel in situ are next planned for the DVS functionalized thermogel.…”
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Development of the polyglot Asian medicine knowledge graph system by Khoo, Christopher S. G., Stanley-Baker, Michael, Faizah Binte Zakaria, Chen, Jinju, Ang, Shaun Qiao Rou, Huang, Bo

“…The current coverage of the database is mainly traditional Chinese medicines with some Malay and Indonesian data, with plans to extend to other Southeast Asian communities. …”
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