In vitro anti-proliferative mechanism of combination therapy with tannic acid and cisplatin against human osteosarcoma cell line U2OS by Kasiram, Mohamad Zahid Mohd

“…Mechanistically, anti-proliferative and apoptotic effect of TA and its combination with cisplatin on U2OS cells were suggested to be modulated via JNK1 inhibition, ERK2 activation, and intrinsic apoptotic pathways. The findings suggest the potential inclusion of TA in cisplatin-based chemotherapy for osteosarcoma and warrant further investigation…”
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Target Design and Optimizations for Spent Fuel Transmutation by Tukharyan, Grigor

“…A proposed tank design with a lead/Tc-99 target that is surrounded by LLFP pins and heavy water is considered for the spallation study. …”
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Interplanetary space weather effects on Lunar Reconnaissance Orbiter avalanche photodiode performance. by Clements, E. B., Carlton, A. K., Joyce, C. J., Schwadron, N. A., Spence, H. E., Sun, X., Cahoy, K.

“…We compare noise data from the Lunar Reconnaissance Orbiter (LRO) Lunar Orbiter Laser Altimeter (LOLA) SiAPDs with radiation measurements from the onboard Cosmic Ray Telescope for the Effects of Radiation (CRaTER) instrument. We did not find any evidence to support radiation as the cause of changes in detector threshold voltage during radiation storms, both for transient detector noise and long-term average detector noise, suggesting that the approximately 1.3 cm thick shielding (a combination of titanium and beryllium) of the LOLA detectors is sufficient for SiAPDs on interplanetary missions with radiation environments similar to what the LRO experienced (559 cGy of radiation over 4 years).…”
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Actionable Auditing: Investigating the Impact of Publicly Naming Biased Performance Results of Commercial AI Products by Buolamwini, Joy, Raji, Inioluwa Deborah

“…Within 7 months of the original audit, we find that all three targets released new API versions. …”
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The International Affiliation Network of YouTube Trends by Platt, Edward, Bhargava, Rahul, Zuckerman, Ethan

“…Consistent with existing work on video popularity, we find that long trending times within one nation do not necessarily translate to reaching a wide global audience. …”
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Association between COVID-19 outcomes and mask mandates, adherence, and attitudes by Adjodah, Dhaval, Dinakar, Karthik, Chinazzi, Matteo, Fraiberger, Samuel P., Pentland, Alex, Bates, Samantha, Staller, Kyle, Vespignani, Alessandro, Bhatt, Deepak L.

“…These effects are large, corresponding to 14% of the highest recorded number of cases, 13% of deaths, and 7% of admission proportion. We also find that mask mandates are linked to a 23.4 percentage point increase in mask adherence in four diverse states. …”
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Branch-and-bound performance estimation programming: a unified methodology for constructing optimal optimization methods by Das Gupta, Shuvomoy, Van Parys, Bart P. G., Ryu, Ernest K.

“…Finally, we use the BnB-PEP methodology to find proofs with potential function structures, thereby systematically generating analytical convergence proofs.…”
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Probing axion-like particles at the Electron-Ion Collider by Balkin, Reuven, Hen, Or, Li, Wenliang, Liu, Hongkai, Ma, Teng, Soreq, Yotam, Williams, Mike

“…In a prompt-decay search, we find that the EIC can set the most stringent bound for <jats:italic>m</jats:italic><jats:sub><jats:italic>a</jats:italic></jats:sub> ≲ 20 GeV and probe the effective scales Λ ≲ 10<jats:sup>5</jats:sup> GeV. …”
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Petz recovery from subsystems in conformal field theory by Vardhan, Shreya, Wei, Annie Y., Zou, Yijian

“…In the case where A and C are far apart, we find a surprising non-commutativity of the replica trick with the OPE limit. …”
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Assessing compounding climate-related stresses and development pathways on the power sector in the central U.S. by Gurgel, Angelo Costa, Reilly, John, Morris, Jennifer, Schlosser, C. Adam, Gao, Xiang, Yuan, Mei, Tapia-Ahumada, Karen

“…Potential supply gaps range from 5% in the North Central region under mild changes in climate to 21% in the Lakes-Mid Atlantic region under more severe climate change. We find increases in electricity demand to be more important in determining the size of the potential supply gap than stresses on power generation, while larger shares of renewables in the power system contribute to lower supply gaps. …”
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Anomalous crystalline ordering of particles in a viscoelastic fluid under high shear by Sun, Sijie, Xue, Nan, Aime, Stefano, Kim, Hyoungsoo, Tang, Jizhou, McKinley, Gareth H., Stone, Howard A., Weitz, David A.

“…Here, we use a fully immersed parallel plate geometry to measure the high-shear-rate behavior of a suspension of particles in a viscoelastic fluid. We find an unexpected separation of the particles within the suspension resulting in the formation of a layer of particles in the center of the cell. …”
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Parallel Algorithms for Hierarchical Nucleus Decomposition by Shi, Jessica, Dhulipala, Laxman, Shun, Julian

“…Nucleus decompositions have been shown to be a useful tool for finding dense subgraphs. The coreness value of a clique represents its density based on the number of other cliques it is adjacent to. …”
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Crossover from viscous fingering to fracturing in cohesive wet granular media: a photoporomechanics study by Meng, Yue, Li, Wei, Juanes, Ruben

“…We inject water into the oil-filled photoelastic granular pack, varying the injection flow rate, defending-fluid viscosity, and intergranular cohesion. We find two different modes of fluid invasion: viscous fingering, and fracturing with leak-off of the injection fluid. …”
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Brief Report: Quantifying Speech Production Coordination from Non- and Minimally-Speaking Individuals by Talkar, Tanya, Johnson, Kristina T., Narain, Jaya, Maes, Pattie, Picard, Rosalind W., Quatieri, Thomas F.

“…Results We specifically find that frustrated and dysregulated utterances show similar correlation structure outputs, especially when compared to self-talk, request, and delighted utterances. …”
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Single-Shot Quantitative Polarization Imaging of Complex Birefringent Structure Dynamics by Ge, Baoliang, Zhang, Qing, Zhang, Rui, Lin, Jing-Tang, Tseng, Po-Hang, Chang, Che-Wei, Dong, Chen-Yuan, Zhou, Renjie, Yaqoob, Zahid, Bischofberger, Irmgard, So, Peter T. C.

“…We envision that PSIM will find a broad range of applications in quantitative material characterization under dynamical conditions.…”
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Microscale advection governs microbial growth and oxygen consumption in macroporous aggregates by Shen, Rachel, Borer, Benedict, Ciccarese, Davide, Salek, M. Mehdi, Babbin, Andrew R.

“…Here, we quantify how pores through microenvironments that permit flow can elevate nutrient supply to the resident bacterial community using a microfluidic experimental system and gain further insights from coupled population-based and computational fluid dynamics simulations. We find that the microscale structure determines the relative contribution of advection vs diffusion, and even a modest flow through a pore in the range of 10 µm s−1 can increase the carrying capacity of a microenvironment by 10%. …”
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Feasibility Analysis of On-Orbit Debris Detection Using Commercial Star Trackers by Shtofenmakher, Allan, Balakrishnan, Hamsa

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Risk-Aware Framework Development for Disruption Prediction: Alcator C-Mod and DIII-D Survival Analysis by Keith, Zander, Nagpal, Chirag, Rea, Cristina, Tinguely, R. Alex

“…While this study finds cases where disruptive conditions are not predicted, there are instances where the desired outcome is produced. …”
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Safety assessment using computer experiments and surrogate modeling: Railway vehicle safety and track quality indices by Neves Costa, João, Ambrósio, Jorge, Andrade, António R., Frey, Daniel

“…Finally, an example illustrates how these surrogates can be used to find which safety quantities govern safety and define track geometry limits directly linked to vehicle safety.…”
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Electrolyte Dependence of Li+ Transport Mechanisms in Small Molecule Solvents from Classical Molecular Dynamics by Crabb, Emily, Aggarwal, Abhishek, Stephens, Ryan, Shao-Horn, Yang, Leverick, Graham, Grossman, Jeffrey C.

“…Using classical molecular dynamics simulations, we find that a vehicular mechanism can be increasingly preferred with a decreasing solvent viscosity and increasing interaction energy between the solvent and Li+. …”
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