Electrochemical polymerase chain reaction using electroactive graphene oxide nanoparticles as detection labels by Ang, Wei Li, Seah, Xin Yun, Koh, Puay Ching, Caroline, Caroline, Bonanni, Alessandra

“…From that, the extrapolated cycle threshold value showed a linear relationship with the initial number of copies of target DNA. Through the findings, electroactive nanocarbon material demonstrated high potential as electrochemical label for PCR, with the electrochemical signals produced directly correlated to the amount of PCR product. …”
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Direct reuse of electronic plastic scraps from computer monitor and keyboard to direct stem cell growth and differentiation by Shi, Pujiang, Tan, Chiew Kei, Wu, Zhuoran, Gabriel, Jean-Christophe P., Srinivasan, Madhavi, Lee, Jong-Min, Tay, Chor Yong

“…Interestingly, compared to commercial tissue-culture treated plastics and in a competitive adipogenic and osteogenic differentiation environment, ADSCs cultured on the keyboard and light diffuser plastics favoured bone cells formation while the grating-like microstructures of the prismatic sheet promoted fat cells differentiation via the process of contact guidance. Our findings point to the real possibility of utilizing discarded computer plastics as a "waste-to-resource" material to programme stem cell fate without further processing nor biochemical modification, thus providing an innovative second-life option for E-plastics from personal computers.…”
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Systematic study of short circuit activation on the performance of PEM fuel cell by Zhang, Caizhi, Liu, Hao, Zeng, Tao, Chen, Jiawei, Lin, Pengfeng, Deng, Bo, Liu, Fujian, Zheng, Yifeng

“…However, the smallest impact is short-circuit interval. Another finding is that the five activation parameters are not independent, so the optimal activation parameter value needs to be analyzed in combination with the operating conditions. …”
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The cancellation heuristic in intertemporal choice shifts people's time preferences by Sengupta, Arjun, Savani, Krishna

“…Furthermore, we provide evidence of the underlying mechanism-people's intertemporal decisions shifted to a greater extent in the cancellation condition, particularly if their marginal utility diminished faster. The findings indicate that two features of human psychology-diminishing marginal utility and the cancellation heuristic-can be simultaneously utilized to nudge people to make decisions that would be better for them in the long run.…”
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Value-added products from thermochemical treatments of contaminated e-waste plastics by Das, Pallab, Gabriel, Jean-Christophe P., Tay, Chor Yong, Lee, Jong-Min

“…A basic framework of the existing processes has been established by reviewing the most interesting findings in recent times and the prospects that they open in the field recycling of e-waste plastics.…”
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Facial action unit detection using attention and relation learning by Shao, Zhiwen, Liu, Zhilei, Cai, Jianfei, Wu, Yunsheng, Ma, Lizhuang

“…Attention mechanism has recently attracted increasing attentions in the field of facial action unit (AU) detection. By finding the region of interest of each AU with the attention mechanism, AU-related local features can be captured. …”
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Mitofusins Mfn1 and Mfn2 are required to preserve glucose- but not incretin-stimulated β-cell connectivity and insulin secretion by Georgiadou, Eleni, Muralidharan, Charanya, Martinez, Michelle, Chabosseau, Pauline, Akalestou, Elina, Tomas, Alejandra, Yong, Fiona Su Wern, Stylianides, Theodoros, Wretlind, Asger, Legido-Quigley, Cristina, Jones, Ben, Lopez-Noriega, Livia, Xu, Yanwen, Gu, Guoqiang, Alsabeeh, Nour, Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Ali, Yusuf, Soleimanpour, Scott A., Linnemann, Amelia K., Rodriguez, Tristan A., Rutter, Guy A.

“…Mitochondrial fusion and fission cycles are thus essential in the β-cell to maintain normal glucose, but not incretin, sensing. These findings broaden our understanding of the roles of mitofusins in β-cells, the potential contributions of altered mitochondrial dynamics to diabetes development, and the impact of incretins on this process.…”
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Comprehensive analysis of feature extraction methods for emotion recognition from multichannel EEG recordings by Yuvaraj, Rajamanickam, Thagavel, Prasanth, Thomas, John, Fogarty, Jack, Ali, Farhan

“…The stability of these findings across the five different datasets also indicate that FD features derived from EEG data are reliable for emotion recognition. …”
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Metal mediated high performance antimicrobial hydrogel films for wound infection management: Zn, Cu, and Mg versus Ag and Au by Sen, Raj Kumar., Prabhakar, Priyanka, Mayandi, Venkatesh, Dwivedi, Neeraj, Yadav, Amit K., Solanki, Pratima R., Gupta, Ayush, Gowri, V. S., Lakshminarayanan, Rajamani, Verma, Navin Kumar, Mondal, D. P., Srivastava, Avanish Kumar, Dhand, Chetna

“…Strikingly, the Cu and Zn integrated hydrogels demonstrated broad-spectrum antimicrobial properties. The findings of this work thus reveal a more cost-effective, sustainable, and environmentally friendly approach to designing high-value-added wound care products.…”
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Optically detected magnetic resonance spectroscopic analyses on the role of magnetic ions in colloidal nanocrystals by Dehnel, Joanna, Harchol, Adi, Barak, Yahel, Meir, Itay, Horani, Faris, Shapiro, Arthur, Strassberg, Rotem, de Mello Donegá, Celso, Demir, Hilmi Volkan, Gamelin, Daniel R., Sharma, Kusha, Lifshitz, Efrat

“…The information extracted from the analyses of the ODMR spectra in those studies exposes fundamental physical parameters, such as g-factors, exchange coupling constants, and hyperfine interactions, together providing insights into the nature of the carrier (electron, hole, dopant), its local surroundings (isotropic/anisotropic), and spin dynamics. The findings illuminate the importance of ODMR spectroscopy in advancing our understanding of the role of magnetic ions in semiconductor nanocrystals and offer valuable knowledge for designing magnetic materials intended for various spin-related technologies.…”
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Lower serum uric acid and impairment of right cerebral hemisphere structural brain networks are related to depressive symptoms in cerebral small vessel disease: a cross-sectional s... by Yu, Lei, Yi, Ming, Guo, Jiayu, Li, Jinbiao, Zeng, Huixing, Cui, Liqian, Xu, Xiangming, Liu, Gang, Fan, Yuhua, Zeng, Jinsheng, Xing, Shihui, Chen, Yicong, Wang, Meng, Tan, Shuangquan, Jin, Leow Yi, Kumar, Dilip, Vipin, Ashwati, Ann, Soo See, Fatin Zahra Binte Zailan, Sandhu, Gurveen Kaur, Kandiah, Nagaendran, Dang, Chao

“…HAMD scores were significantly associated with nodal network metrics in the right cerebral hemisphere. Our findings suggested that lower SUA levels are significantly associated with disrupted structural brain networks in the right cerebral hemisphere of patients with SVD who have depressive symptoms.…”
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Effect mechanism of Er content variations on the mechanical and corrosion properties of T6 state Al–Mg–Si-xEr sheets by Cao, Puli, Zhu, Daibo, Wu, Na, Ouyang, Lingxue, Li, Chengbo, Liu, Yang, Zhu, Yulong, Liu, Jirong

“…This work investigates the influence of erbium (Er) content on the microstructure, mechanical properties, and corrosion behavior of T6 state AA6061 sheets. The findings reveal that nanoscale Al(Fe, Mn)Si particles are the main factors hindering dislocation motion and grain boundaries (GBs) migration. …”
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Phonon stability boundary and deep elastic strain engineering of lattice thermal conductivity by Shi, Zhe, Tsymbalov, Evgenii, Shi, Wencong, Barr, Ariel, Li, Qingjie, Li, Jiangxu, Chen, Xing-Qiu, Dao, Ming, Suresh, Subra, Li, Ju

“…Computational work combining ab initio calculations and machine learning (ML) algorithms has further demonstrated that the bandgap of diamond can be altered significantly purely by reversible elastic straining. These findings open up unprecedented possibilities for designing materials and devices with extreme physical properties and performance characteristics for a variety of technological applications. …”
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Dynamic traffic safety risk assessment in road tunnel entrance zone based on drivers' psychophysiological perception states: methodology and case-study insights by Niu, Jia'an, Liang, Bo, Wong, Yiik Diew, He, Shiyong, Qin, Can, Wen, Sen

“…The results show that the traffic safety risk identification accuracy of the machine learning model proposed in this study reaches 95.13%, and the model can dynamically assess the real-time driving risk level. The findings have practical implications for the prevention of traffic crashes in the tunnel entrance zone and the realization of safe and stable operation of road tunnels.…”
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Motor adaptation with passive machines: A first study on the effect of real and virtual stiffness by Tommasino, Paolo, Melendez-Calderon, A., Burdet, E., Campolo, Domenico

“…In particular, we tested 20 healthy subjects under two different real stiffness conditions (Stiff Channel vs Compliant Channel) and two different virtual conditions (Viscous vs Springy). Our main finding is that compliance of the channel favours a better adaptation featured with less lateral errors and longer retention of the after-effect. …”
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Mechanisms of Yersinia YopO kinase substrate specificity by Lee, Wei Lin, Singaravelu, Pavithra, Wee, Sheena, Xue, Bo, Ang, Khay Chun, Gunaratne, Jayantha, Grimes, Jonathan M., Swaminathan, Kunchithapadam, Robinson, Robert C.

“…Using artificial substrates we clarified YopO’s substrate length requirements and its phosphorylation consensus sequence. These findings provide fresh insight into the mechanism of the YopO kinase and demonstrate that YopO executes a specific strategy targeting actin-modulating proteins, across multiple functionalities, to compete for control of their native phospho-signaling, thus hampering the cytoskeletal processes required for macrophage phagocytosis.…”
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Identification and characterization of roseltide, a knottin-type neutrophil elastase inhibitor derived from hibiscus sabdariffa by Nguyen, Giang Kien Truc, Tam, James Pingkwan, Loo, Shining, Kam, Antony, Xiao, Tianshu, Liu, Chuan Fa

“…Taken together, our findings demonstrate that roseltide rT1 is a novel knottin-type neutrophil elastase inhibitor with therapeutic potential for neutrophil elastase associated diseases.…”
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Neurobiology of culturally common maternal responses to infant cry by Rigo, Paola, Bornstein, Marc H., Putnick, Diane L., Esposito, Gianluca, Swain, James E., Suwalsky, Joan T. D., Su, Xueyun, Du, Xiaoxia, Zhang, Kaihua, Cote, Linda R., De Pisapia, Nicola, Venuti, Paola

“…Culturally common responses to own infant cry coupled with corresponding fMRI findings to own infant and to generic infant cries identified specific, common, and automatic caregiving reactions in mothers to infant vocal expressions of distress and point to their putative neurobiological bases. …”
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Epithelial-mesenchymal transition of cancer cells using bioengineered hybrid scaffold composed of hydrogel/3D-fibrous framework by Pal, Mintu, Chen, Huizhi, Lee, Bae Hoon, Lee, Justin Yin Hao, Yip, Yun Sheng, Tan, Nguan Soon, Tan, Lay Poh

“…In this study, we focused on two major points (i) designing and fabrication of 3D hybrid scaffolds comprising electrospun fibers with cancer cells embedded within hydrogels, and (ii) determining the potential roles of 3D hybrid scaffolds associated with EMT in cancer progression and metastasis. Our findings revealed that 3D hybrid scaffold enhances cell proliferation and induces cancer cells to undergo EMT, as demonstrated by significant up-regulation of EMT associated transcriptional factors including Snail1, Zeb1, and Twist2; and mesenchymal markers whereas epithelial marker, E-Cadherin was downregulated. …”
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Modeling the change of beach profile under tsunami waves : a comparison of selected sediment transport models by Li, Linlin, Huang, Zhenhua

“…For real tsunamis, high suspended sediment concentration may occur, and density stratification and hindered settling effect play an important role; therefore, Delft3D, with both hindered settling and density stratification being considered, may perform better than XBeach. The findings reported here will be useful for researchers and practitioners working on tsunami hazard mitigation.…”
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