The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator by Wong, Brandon Han Siang, Shim, Heesung, Goay, Stephanie Shee Min, Ong, Seow Theng, Nur Ayuni Binte Muhammad Taib, Chai, Kelila Xin Ye, Lim, Kerry, Huang, Dachuan, Ong, Choon Kiat, Vaiyapuri, Thamil Selvan, Cheah, Yeong Cheng, Wang, Yulan, Wulff, Heike, Webster, Richard David, Shelat, Vishalkumar G., Verma, Navin Kumar

“…Here, we aimed to identify and characterize an activator that would augment KCa3.1 currents without affecting other channels. We synthesized five quinoline derivatives and used electrophysiology to screen them on KCa3.1 and a panel of 14 other ion channels. …”
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Occurrence, human exposure and dynamics of phthalates in ACMV indoor environments : method development and field studies by Chen, Ailu

“…The study investigates occurrence of five typical phthalates in 24 ACMV indoor environments that are covered with different flooring materials. …”
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新加坡高校人才战略的理念建构和实践运作 - 以南洋理工大学为例 = Formulation and implementation of talent strategy in higher education : a case study of Nanyang Technological University in Singapore... by 刘宏 Liu Hong, 贾丽华 Jia Lihua, 范昕 Fan Xin

“…This article is structured into five parts. The first section discusses the formulation of talent strategies in Singapore. …”
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Examining diabetes management apps recommended from a Google search : content analysis by Jimenez, Geronimo, Lum, Elaine, Car, Josip

“…We found a wide variation in the type and the number of diabetes management features in the recommended apps. Five apps required payment to be used. Two-thirds of the apps had blood glucose management features, and less than half had medication management features. …”
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Understanding the justifications for food policies through political theory: a method for public policy analysis by Thomas, O

“…In other words, this thesis addresses the following question: How can looking at political theories help us understand the justifications for food policies?</p> <p>I examined five case studies of sugar reduction interventions. …”

Pathogen diversity and antimicrobial resistance transmission of Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study... by Dyson, ZA, Ashton, PM, Khanam, F, Chunga Chirambo, A, Shakya, M, Meiring, JE, Tonks, S, Karkey, A, Msefula, C, Clemens, JD, Dunstan, SJ, Baker, S, Dougan, G, Pitzer, VE, Basnyat, B, Qadri, F, Heyderman, RS, Gordon, MA, Holt, KE, Pollard, AJ, STRATAA Study Group

“…Azithromycin-resistance mutations in acrB were rare, appearing only in Dhaka (five [1%] of 452). Phylogenetic analyses showed that most cases derived from pre-existing, locally established pathogen variants; 702 (98%) of 713 drug-resistant infections resulted from local circulation of AMR variants, not imported variants or recent de novo emergence; and pathogen variants circulated across age groups. 479 (66%) of 731 cases clustered with others that were indistinguishable by point mutations; individual clusters included multiple age groups and persisted for up to 2·3 years, and AMR determinants were invariant within clusters.…”

A preliminary study on the effects of substituting fishmeal with defatted black soldier fly (Hermetia illucens) larval meal on Asian seabass (Lates calcarifer) juveniles: Growth pe... by Liu, Yun, Andin, Victor Charlie, Chor, Wei-Kang, Gunasekaran, Baskaran, Chong, Chou-Min, Lee, Po-Tsang, Loh, Jiun-Yan

“…After a 7-day challenge test with V. parahaemolyticus, the cumulative mortality rates of the BSFL5 and BSFL10 groups, respectively, dropped to 5.20%, 5.28% compared to the control group's 16.88%; however, the mortality rates of BSFL15 (34.67%) and BSFL20 (41.77%) groups were found to be significantly (p < 0.05) increased. …”

Cytotoxicity and mechanisms of action of Zerumbone-loaded nanostructured lipid carrier in triple negative breast cancer cells, MDA-MB-231 by Hosseinpour, Mahnaz

“…According to the Malaysian National Cancer Registry (2006), breast cancer is one of the five most common cancers amongst Malaysian women. …”
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RNA interference silencing of interleukin-6 in mesenchymal stromal cells and antitumour efficacy against multiple myeloma cells by Teoh, Hoon Koon

“…MSC transduced with IL-6 shRNA also inhibited U266 growth significantly to 53.1% and 74.4% by day five through cell-substrate and cell-cell interactions respectively (P<0.05, ANOVA). …”
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Rapid eye movement sleep deprivation induces vascular endothelial dysfunction in rats: roles of oxidative stress-mediated nitric oxide signalling and vitamin c supplementation by Nawi, Afifah

“…The beneficial effects of vitamin C were also evaluated. Thirty-five (35) adult male Sprague-Dawley rats were equally divided into 5 groups (n=7): free-moving control rats (FMC), REM sleep-deprived rats for 72-h (72-h REMsd), tank control rats (TC), sleep recovered for 72-h after 72-h of REMsd (SR), and 72-h REMsd pretreated with vitamin C (RVC). …”
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The Use of Artificial Intelligence in Digital Marketing : Competitive Strategies and Tactics / by Teixeira, Sandrina, 1975-, editor 655945, Remondes, Jorge, 1971-, editor 655946, IGI Global (Online service) 631983

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An implantable soft robotic ventilator augments inspiration in a pig model of respiratory insufficiency by Hu, Lucy, Bonnemain, Jean, Saeed, Mossab Y., Singh, Manisha, Quevedo Moreno, Diego, Vasilyev, Nikolay V., Roche, Ellen T.

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Additive manufacturing of interlocking glass masonry units by Massimino, Daniel, Townsend, Ethan, Folinus, Charlotte, Stern, Michael, Becker, Kaitlyn

“…The glass 3D printer employed in this study is capable of printing a maximum volume of 32.5 × 32.5 × 38 cm–suitable for producing full-size masonry units. …”
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Characterization of Nile Red-Stained Microplastics through Fluorescence Spectroscopy by Prasad, Suparnamaaya, Bennett, Andrew, Triantafyllou, Michael

“…Microplastics (MPs), typically defined as plastic fragments smaller than 5 mm, are pervasive in terrestrial and marine ecosystems. …”
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Evaluation of Enterococcus hirae isolated from vegetable wastes as probiotic and improvement of immune response in African catfish (Clarias spp.) by Hamid, Nur Hidayahanum

“…Both E. hirae strains were active at different levels of NaCl (0 to 6.5%) and also, at various temperatures ranging from 5 to 45°C, but no growth at 55°C. …”
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Tree-based Data Replay for More Efficient LLM Continual Learning by Bailey, Brian

“…Models trained under restrictive replay conditions—excluding data from parent nodes—achieved perplexity scores within 1.5% of the baseline and reduced training time by up to 20%. …”
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Digital Techniques for Heritage Presentation and Preservation / by Mukhopadhyay, Jayanta, editor 518135, Sreedevi, Indu, editor 642824, Chanda, Bhabatosh, editor 399240, Chaudhury, Santanu, editor 642825, Namboodiri, Vinay P., editor 642826

MORNING, NOON & NIGHT / by Sheldon, Sidney, author 498270

Build a Large Language Model (From Scratch) / by Raschka, Sebastian, author 656094

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Polymer-Inorganic Nanostructured Composites Based on Amorphous Silica, Layered Silicates, and Polyionenes / by Sukhyy, Kostyantyn M., 1976-, author 655484, Belyanovskaya, Elena A., 1972-, author 655485, IGI Global (Online service) 631983

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