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    Lancing drug reservoirs into subcutaneous fat to combat obesity and associated metabolic diseases by Than, Aung, Duong, Phan Khanh, Zan, Ping, Liu, Junjie, Leow, Melvin Khee-Shing, Chen, Peng

    Published 2021
    “…Specifically, ultrathin, core-shelled, and lance-shaped polymeric drug reservoirs (micro-lances [MLs]) are readily fabricated by a thermal pressing molding method and totally implanted into subcutaneous fat by lancing through the skin. Using a diet-induced obese mouse model, it is shown that the development of obesity and associated metabolic disorders is effectively inhibited by applying therapeutic core-shelled MLs once every 2 weeks. …”
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    Journal Article