Mass spectrometry imaging highlights dynamic patterns of lipid co-expression with Aβ plaques in mouse and human brains by Huang, Helen Xuexia, Inglese, Paolo, Tang, Jiabin, Yagoubi, Riad, Correia, Gonçalo D. S., Horneffer-van der Sluis, Verena M., Camuzeaux, Stephane, Wu, Vincen, Kopanitsa, Maksym V., Willumsen, Nanet, Jackson, Johanna S., Barron, Anna M., Saito, Takashi, Saido, Takaomi C., Gentlemen, Steve, Takats, Zoltan, Matthews, Paul M.

“…Likewise, in human donors with varying Braak stages, similar studies of cortical sections revealed co-expression of lysophospholipids and ceramides around Aβ plaques in AD (Braak stage V/VI) but not in earlier Braak stage controls. Our findings in mice provide evidence of temporally and spatially heterogeneous differences in lipid composition as local and global Aβ-related pathologies evolve. …”
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Selective photoelectrochemical oxidation of glycerol to glyceric acid on (002) facets exposed WO3 nanosheets by Xiao, Yonghao, Wang, Mengran, Liu, Dong, Gao, Jiajian, Ding, Jie, Wang, Huan, Yang, Hong Bin, Li, Fuhua, Chen, Mengxin, Xu, Yangsen, Xu, Danyun, Zhang, Yun-Xiao, Fang, Shaofan, Ao, Xin, Wang, Jingyu, Su, Chenliang, Liu, Bin

“…Compared to (200) facets exposed WO3 , a combination of experiments and theoretical calculations indicates that the superior performance of selective glycerol oxidation mainly originates from the better charge separation and prolonged carrier lifetime resulted from the plenty of surface trapping states, lower energy barrier of the glycerol-to-GLYA reaction pathway, more abundant active sites and stronger oxidative ability of photogenerated holes on the (002) facets exposed WO3 . Our findings show great potential to significantly contribute to the sustainable and environmentally friendly chemical processes via designing high performance photoelectrochemical cell via facet engineering for renewable feedstock transformation.…”
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Profiling pro-inflammatory proteases as biomolecular signature of material-induced subcutaneous host response in immuno-competent mice by Tran, Nam M. P., Truong, Anh T. H., Nguyen, Dang T., Dang, Tram Thuy

“…This study also demonstrates the predictive utility of protease activity as a non-invasive, pro-inflammatory parameter for evaluation of the anti-inflammatory effects of model bioactive compounds on material-induced host response. Overall, our findings provide new insights into protease presence in material-induced immune responses, facilitating future biomaterial assessment to evoke appropriate host responses for implant applications.…”
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Optical quantum sensing for agnostic environments via deep learning by Zhou, Zeqiao, Du, Yuxuan, Yin, Xu-Fei, Zhao, Shanshan, Tian, Xinmei, Tao, Dacheng

“…Extensive experiments are conducted to investigate the performance of DQS under different settings up to eight photons. Our findings not only offer a different lens through which to accelerate optical quantum sensing tasks but also catalyze future research integrating deep learning and quantum mechanics.…”
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Customer co-creation in B2C e-commerce: does it lead to better new products? by Pee, Loo Geok

“…This is also one of the earliest studies to report empirical evidence for the impact of customer co-creation in e-commerce. The findings offer specific insights into the co-creation tasks and NPD stages to open for customer co-creation in practice.…”
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Adsorption of hyaluronic acid on solid supports: Role of pH and surface chemistry in thin film self-assembly by Choi, Jae-Hyeok, Kim, Seong-Oh, Linardy, Eric, Dreaden, Erik C., Zhdanov, Vladimir P., Hammond, Paula T., Cho, Nam-Joon

“…The observed specifics of the kinetics of HA adsorption, including a short initial linear phase and subsequent long non-linear phase, were described by using a mean-field kinetic model taking HA diffusion limitations and reconfiguration in the adsorbed state into account. The findings extend the physicochemical background of design strategies for improving the use of passive HA adsorption for surface modification applications.…”
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p27 is regulated independently of Skp2 in the absence of Cdk2 by Kaldis, Philipp, Kotoshiba, Shuhei, Gopinathan, Lakshmi, Pfeiffenberger, Elisabeth, Rahim, Anisa, Vardy, Leah Karen Anne, Nakayama, Keiko, Nakayama, Keiichi I.

“…Ablation of other ubiquitin ligases for p27 such as KPC1, DDB1, and Pirh2 did not restore stability of p27 in Cdk2−/−Skp2−/− MEFs. Our findings point towards novel and alternate pathways for p27 regulation.…”
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Virus-specific T lymphocytes home to the skin during natural dengue infection by Rivino, Laura, Kumaran, Emmanuelle A., Thein, Tun-Linn, Too, Chien Tei, Gan, Victor Chih Hao, Hanson, Brendon J., Wilder-Smith, Annelies, Bertoletti, Antonio, Gascoigne, Nicholas R. J., Lye, David Chien, Leo, Yee Sin, Akbar, Arne N., Kemeny, David M., MacAry, Paul A.

“…The juxtaposition of dengue-specific T cells with virus-permissive cell types at sites of possible dengue exposure represents a previously uncharacterized form of immune surveillance for this virus. These findings suggest that vaccination strategies may need to induce dengue-specific T cells with similar homing properties to provide durable protection against dengue viruses.…”
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High expression of MnSOD promotes survival of circulating breast cancer cells and increases their resistance to doxorubicin by Fu, Afu, Ma, Shijun, Wei, Na, Tan, Blanche Xiao Xuan, Tan, Ern Yu, Luo, Kathy Qian

“…Specific siRNA-mediated MnSOD knockdown reversed all three phenotypes. Our findings therefore suggest that MnSOD plays an important integrative role in supporting cancer cell survival in circulation, metastasis, and doxorubicin resistance. …”
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Robust design of LCL filters for single-current-loop-controlled grid-connected power converters with unit PCC voltage feedforward by Li, Xiaoqiang, Fang, Jingyang, Tang, Yi, Wu, Xiaojie

“…Moreover, another interesting finding is that the feedforward control can help maintain a high current control bandwidth under grid impedance variation. …”
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Geometric shapes effect of in-duct perforated orifices on aeroacoustics damping performances at low Helmholtz and Strouhal number by Zhao, Dan, Ji, Chenzhen, Wang, Bing

“…The measured minimum reflection coefficient Rmin occurs at Ma ≈ 0.024. This experimental finding is consistent with the quasi-steady prediction.…”
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“A wound that has been festering since 2007”: The Burma/Myanmar naming controversy and the problem of rarely challenged assumptions on Wikipedia by Luyt, Brendan

“…Design/methodology/approach: The author’s approach to the study of the Wikipedia talk pages devoted to the Burma/Myanmar naming controversy is qualitative in nature and explores the debate over sources through textual analysis. Findings: Editors brought to their work a number of underlying assumptions including the primacy of the nation-state and the nature of a “true” encyclopedia. …”
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Enhanced indirect ferromagnetic p-d exchange coupling of Mn in oxygen rich ZnO:Mn nanoparticles synthesized by wet chemical method by Ilyas, Usman, Rawat, Rajdeep Singh, Tan, T. L., Lee, P., Chen, R., Sun, Handong, Fengji, Li., Zhang, Sam

“…This paper investigates the ferromagnetism in ZnO:Mn powders and presents our findings about the role played by the doping concentration and the structural defects towards the ferromagnetic signal. …”
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Interface and surface cation stoichiometry modified by oxygen vacancies in epitaxial manganite films by Li, Zhi Peng, Bosman, Michel, Yang, Zhen, Ren, Peng, Wang, Lan, Zhu, Weiguang, Dong, Zhili, Foo, Yong Lim, Cao, Liang, Yu, Xiaojiang, Ke, Chang, Breese, Mark B. H., Rusydi, Andrivo

“…The results narrow the selection range of useful oxygen pressures during deposition and demonstrate that accurate cation stoichiometry can only be achieved after oxygen vacancies are eliminated during growth. This finding suggests that the oxygen pressure serves as a tuning parameter for the interfacial dead layers and, hence, for control over device properties.…”
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Socio-demographic characteristics and clinical profile of suicide attempters attending the Emergency Department at a Tertiary Care Hospital in Oman: a retrospective study by Al Khatri, Mahmood, Al Huseini, Salim, Almaqbali, Mandhar, Cucchi, Angie, Al-Saadi, Alkhatib, Al Farsi, Abdulmunim, Jose, Sachin, Al-Sibani, Nasser, Al-Adawi, Samir

“…Although in its infancy, the present research’s findings could lay the groundwork for preventative interventions and programs.…”
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User acceptance of 2D embryology animation: early embryogenesis made easy by Yin, Chin Hui, Jaysri, Faris Hazreen, Wan Mohamed Zuri, Wan Nur Syaziyah, Nasharuddin, Nurul Amelina, Mohd Nor, Nurul Huda, Sa'at, Azmah, Hod, Rafidah, Mohd Nazan, Ahmad Iqmer Nashriq, Mohamad Asri, Siti Fadziyah, Abas, Razif

“…Limitations included the small sample size and focus on a specific embryonic stage, urging further studies with broader participant pools and diverse educational stages for improved generalizability. Conclusion: Our findings underscore the significance of multimedia in medical education and advocate for further refinement of such approaches to foster inclusive and effective learning environments.…”
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Factors associated with depression, anxiety, and satisfaction with life among Malaysian parental caregivers of adolescent psychiatric patients: a cross-sectional study by Cham, Choy Qing, Ibrahim, Norhayati, Kalaman, Clarisse Roswini, Ho, Meng Chuan, Visvalingam, Uma, Ahmad Shahabuddin, Farah, Abd Rahman, Fairuz Nazri, Halim, Mohd Radzi Tarmizi A., Harbajan Singh, Manveen Kaur, Azhar, Fatin Liyana, Yahya, Amira Najiha, Roslan, Samsilah, Siau, Ching Sin

“…Participants answered questionnaires measuring financial strain, caregiver burden, relationship quality, belief in mental illness, perceived COVID-19 stress, satisfaction with health services, depressive symptoms, anxiety symptoms and life satisfaction. Findings revealed that relationship quality among spouses, COVID-19 stress and caregiver burden were significantly correlated with anxiety symptoms, depressive symptoms and satisfaction with life. …”
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Newborn screening for severe combined immunodeficiency in Malaysia: current status, challenges and progress by Chang, Wai Leng, Mohd Noh, Lokman, Abdul Latiff, Amir Hamzah, Woo, Kent Chee Keen, Ismail, Intan Hakimah, Abd Hamid, Intan Juliana, Siniah, Sangeetha, Zainal Abidin, Mohd Azri, Sham, Marina, Mat Ripen, Adiratna, Baharin, Mohd Farid, Abdul Wahab, Asrul, Zainudeen, Zarina Thasneem, Hashim, Ilie Fadzilah, Wong, Yee Ming, Ahmad Shawaludin, Mohamad Qazreen, Ali, Adli

“…All 13 invited experts participated in this study, indicating complete participation from the entire Malaysian immunology fraternity (consisting of eight clinical immunologists and five immunopathologists). Key findings: Several initiatives are ongoing to establish SCID NBS in Malaysia. …”
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Spent coffee grounds enhanced compressive strength of cement mortar: An optimization study by Yee, Jia Jun, Khong, Sheh Ching, Tee, Kong Fah, Jolius, Gimbun, Chin, Siew Choo

“…In recent years, sustainable materials have begun finding their way into cement mortar, with SCG being one. …”
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Seaweed processing: Efficiency, kinetics, and quality attributes under solar drying by Khan, Nida, Sudhakar, Kumarasamy, Rizalman, Mamat

“…Economic analysis revealed an estimated annual profit of USD 2270, indicating the economic viability of the proposed system. The findings suggest that the PV-integrated solar dryer offers a promising alternative to traditional drying methods, providing enhanced efficiency and economic benefits for seaweed farmers.…”
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