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41
Inhalable biomimetic nanomotor for pulmonary thrombus therapy
Published 2024Get full text
Journal Article -
42
Early detection of reduced artemisinin susceptibility in plasmodium falciparum using novel phenotypic indicators
Published 2019“…The changes in eIF2α phosphorylation and DNA damage, appearing shortly after in vitro drug treatment, were successfully detected in malaria parasites, and correlated with artemisinin resistance, demonstrating their potentials in future clinical applications.…”
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Thesis -
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Surface modification of smooth poly (L-lactic acid) films for gelatin immobilization
Published 2013“…Poly(l-lactic acid) (PLLA) is widely used in drug delivery and medical implants. Surface modification of PLLA with functional groups to immobilize gelatin or other extracellular matrix proteins is commonly used to improve its cellular affinity. …”
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Journal Article -
44
Large simple randomized controlled trials—from drugs to medical devices: lessons from recent experience
Published 2025“…They are considered essential to establish definitive evidence of efficacy and safety for new drugs, and whenever possible they should also be the preferred method for investigating new high-risk medical devices. …”
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Roughness-Controlled Self-Assembly of Mannitol/LB Agar Microparticles by Polymorphic Transformation for Pulmonary Drug Delivery
Published 2016“…SEM images coupled with image analysis software reveal that different surface morphology of the microparticles have different drug adhesion mechanisms. Comparison of ACI results and image analysis of SEM images shows that an increase in the particle surface roughness can increase the fine particle fractions (FPFs) using the rod-covered mannitol microparticles as drug carriers. …”
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Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction
Published 2023“…Several patient-derived models have been established lately for the prediction of drug response. However, each of these models has its limitations that impede their clinical application. …”
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Journal Article -
49
Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers
Published 2016“…The studies described in this thesis were undertaken to evaluate the application of paper spray mass spectrometry for direct analysis of small molecule drugs and biomarker in dried matrix spot samples. …”
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Thesis -
50
Janus particle preparation through UV-induced partial photodegradation of spin-coated particle films
Published 2022“…Photocatalytic titanium dioxide particles prefunctionalized with a surface coating were assembled as particle films via spin-coating on a substrate. The particle films were placed directly under an ultraviolet light source, which induced the photodegradation of the surface coating only on the particle surfaces exposed to the light. …”
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Journal Article -
51
Spatially controlled molecular encapsulation in natural pine pollen microcapsules
Published 2020Get full text
Journal Article -
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Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY)
Published 2024“…These screens reveal antifungal drug targets, transporters responsible for drug uptake or efflux, as well as metabolic, signalling and trafficking pathways affecting antifungal susceptibility. …”
Thesis -
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Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo...
Published 2014“…In part II, my first project is the development of novel drug-loaded nanogels for pH sensitive drug release, which will be described in chapter 3. …”
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Thesis -
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RES.10-001 Making Science and Engineering Pictures, Fall 2014
Published 2017Get full text
Learning Object -
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Cave fever
Published 2018“…It is a 3D animated short film that blends elements of 2D animation techniques, telling a comedic story of a dragon and a goblin.…”
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Final Year Project (FYP) -
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Investigation of blood pressure regulation schemes
Published 2009“…Hence, continuous monitoring and careful control of the infusion of drug is required. Since the middle 1970s, many researches have been conducted using various types of feedback control system to regulate blood pressure through the infusion of antihypertension drug [5]. …”
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Final Year Project (FYP) -
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Sustained delivery of timolol maleate from liposomal nanocarriers
Published 2014“…Liposomes were prepared using thin film hydration and average particle size in the range of around 100 nm was prepared using a bench top extruder and drug was actively loaded by ammonium sulphate gradient loading technique. …”
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Final Year Project (FYP)