NMR structure and activity relationship of defensin-analogous peptides by Bai, Yang

“…Despite intensive research, detailed bactericidal and cytotoxic mechanisms of AMPs are still largely unknown. In this thesis, molecular template evolution based on the peptide sequence modifications, biophysical studies using fluorescence labeling and NMR spectroscopy, virtual screening utilizing large scale molecular dynamics simulations are exploited for rational antimicrobial drug discovery. …”
Get full text

Quality of life and healthcare service utilization among methadone maintenance patients in a mountainous area of Northern Vietnam by Nguyen, Long Hoang, Nguyen, Lan Huong Thi, Boggiano, Victoria L., Hoang, Canh Dinh, Van Nguyen, Hung, Le, Huong Thi, Le, Hai Quan, Tran, Tho Dinh, Tran, Bach Xuan, Latkin, Carl A., Zary, Nabil, Vu, Minh Thuc Thi

“…Background: The expansion of methadone maintenance treatment in mountainous areas in still limited and little is known about its health impacts on drug users. …”
Get full text
Get full text

Detection of florfenicol resistance in opportunistic Acinetobacter spp. infections in rural Thailand by Tan, Bernice Siu Yan, Mohan, Lalit, Watthanaworawit, Wanitda, Ngamprasertchai, Thundon, Nosten, Francois H., Ling, Clare, Bifani, Pablo

“…Ff shares cross-resistance with chloramphenicol, which is still in use in several countries. Furthermore, by selecting for floR-resistance genes, we may be selecting for and facilitating the zoonotic and reverse zoonotic exchange of other flanking resistance markers between human and animal pathogens or commensals with detrimental public health consequences.…”
Get full text

Synthesis and characterization of silver nanoprism-based nanostructures by Mohammad Mehdi Shahjamali

“…The Ag@Au structure has still single crystalline nature and can have sharp tips depend on the particle's initial morphology. …”
Get full text

Genetic and molecular characterisation of non-tissue culture adapted influenza B viruses detected in Singapore between 2004-2009 by Muhammad Raihan Jumat

“…No mutations conferring drug resistance were noticed among the HA and NA proteins analysed. …”
Get full text

The influence of additives on the delivery of paclitaxel from bioresorbable PLGA films by Huang, Charlotte Liwen.

“…The study of the influences of additives on the drug delivery characteristics from PLGA thin films as a coating on angioplasty balloons was reported in this thesis. …”
Get full text

Multi-Modal Protein Function Prediction using a Joint Embedding Space from Two Graph Neural Networks by Tysinger, Emma P.

“…There’s a growing need for precise and quick computational prediction methods, filling the gap between sequence discovery and functional understanding. …”
Get full text
Get full text

Revealing the biotoxicity of phosphorene oxide nanosheets based on the villin headpiece by Zhang, Wei, Gou, Yuanyuan, Cheng, Li, Dong, Kaiwei, Sheng, Yijie, Ye, Chao, Yang, Xianqing, Mu, Yuguang

“…Phosphorene, a novel member of the two-dimensional nanomaterial family, has demonstrated great potential in biomedical applications, such as photothermal therapy, drug delivery and antibacterial. However, phosphorene is unstable and easily oxidized in an aerobic environment. …”
Get full text