Drug-eluting scaffolds for bone and cartilage regeneration by Lee, Wei Li, Loo, Say Chye Joachim, Huang, Charlotte L.

“…The advancement in strategies for bone and cartilage regeneration have been centralized on a concept that describes the close relationship between osteogenic cells, osteoconductive scaffolds, delivery growth factors and its mechanical environment. …”
Get full text
Get full text

Assessment of PCL/carbon material scaffolds for bone regeneration by Huang, Boyang, Caetano, Guilherme, Wang, Weiguang, Bártolo, Pauko

“…Biomanufacturing is a relatively new research domain focusing on the use of additive manufacturing technologies, biomaterials, cells and biomolecular signals to produce tissue constructs for tissue engineering. For bone regeneration, researchers are focusing on the use of polymeric and polymer/ceramic scaffolds seeded with osteoblasts or mesenchymal stem cells. …”
Get full text
Get full text

Studies on the physicochemical, biomechanical and biological properties of novel decellularized bovine scaffold for bone regeneration by Qabbani, Ali Abdul Qader Hameed Al

“…DCC scaffolds demonstrated better immuno-compatibility and greater bone regeneration potential than DMB, making them a promising option for bone grafting applications.…”
Get full text

Chitosan nanofibrous scaffold with graded and controlled release of ciprofloxacin and BMP-2 nanoparticles for the conception of bone regeneration by Zhang, Sihan, Zhao, Guanglei, Mahotra, Manish, Ma, Shiyuan, Li, Wenrui, Lee, Hiang Wee, Yu, Hong, Sampathkumar, Kaarunya, Xie, Denghui, Guo, Jinshan, Loo, Joachim Say Chye

Get full text

Smart shrinkage solutions? the future of present-day urban regeneration on the inner peripheries of Europe by Mykhnenko, V

Electrical stimulation therapy and HA/TCP composite scaffolds modulate the Wnt pathways in bone regeneration of critical-sized defects by Helaehil, Júlia Venturini, Helaehil, Luiza Venturini, Alves, Laryssa Fernanda, Huang, Boyang, Santamaria-Jr, Milton, Bartolo, Paulo, Caetano, Guilherme Ferreira

Get full text

Assessing public participation in tourism-related urban regeneration: a case of Kochi Heritage City, India by Rahman, Fazlur, Halim, Norhazliza, Abdul Ahad, Abdul Ahad

“…Moreover, it shows difficulties in providing a common state of participation in policy development for tourismrelated urban regeneration. Therefore, the article contributes to a critical examination of public participation in regeneration, which will help in conceptualizing public participation in tourism-related urban regeneration in Kochi. …”
Get full text

Musculoskeletal regeneration: a zebrafish perspective by Kaliya-Perumal, Arun-Kumar, Ingham, Philip William

“…Moreover, clinically relevant muscle and skeletal injury zebrafish models recapitulate mammalian regeneration. Upon muscle injury, quiescent stem cells - known as satellite cells - become activated, proliferate, differentiate and fuse to form new myofibres, while bone fracture results in a phased response involving hematoma formation, inflammation, fibrocartilaginous callus formation, bony callus formation and remodelling. …”
Get full text

Application of MCG-PTCC system on neo-cartilage regeneration by Jiang, Yuwei

“…This project aims to apply the advance fabricated micro-cavities gel (MCG) construct and the innovative phase transfer cell culture (PTCC) strategy to cartilage tissue engineering to realize the self-formation of the bone fide neo-cartilage tissue. The phenomenon called edge flourish (EF) is the underlying principle for successfully creating the MCG-PTCC system. …”
Get full text

Fabrication and characterization of magnetic scaffolds in bone tissue engineering by Chia, Amanda

“…The results are indicative of the excellent physical properties and biocompatibility of PCL-TCP-MNP scaffolds as well as PEMF-induced enhanced bone healing, suggesting potential use of the magnetic scaffolds and PEMF for bone repair and regeneration.…”
Get full text

BMP signaling promotes zebrafish heart regeneration via alleviation of replication stress by Vasudevarao, MD, Posadas Pena, D, Ihle, M, Bongiovanni, C, Maity, P, Geissler, D, Mohammadi, HF, Rall-Scharpf, M, Niemann, J, Mommersteeg, MTM, Redaelli, S, Happ, K, Wu, C, Beisaw, A, Scharffetter-Kochanek, K, D’Uva, G, Malek Mohammadi, M, Wiesmüller, L, Geiger, H, Weidinger, G

“…Pharmacological inhibition of ATM and ATR kinases revealed that DNA damage response signaling is essential for zebrafish heart regeneration. Manipulation of Bone Morphogenetic Protein (BMP)-Smad signaling using transgenics and mutants showed that BMP signaling alleviates cardiomyocyte replication stress. …”

Mode of heparin attachment to nanocrystalline hydroxyapatite affects its interaction with bone morphogenetic protein-2 by Goonasekera, Chandhi S., Jack, Kevin S., Bhakta, Gajadhar, Rai, Bina, Luong-Van, Emma, Nurcombe, Victor, Cool, Simon M., Cooper-White, Justin J., Grøndahl, Lisbeth

“…Heparin has a high affinity for bone morphogenetic protein-2 (BMP-2), which is a key growth factor in bone regeneration. …”
Get full text
Get full text

Electro spun dual structured and three-dimensional biodegradable scaffolds for bone and cartilage tissue engineering by Vidya Chamundeswari Narasimhan

“…For directing bone tissue regeneration, the scaffold was loaded with Ascorbic acid (AA) and ß- Glycerophosphate (ß-Gly) and electro spun prior to MSC seeding. …”
Get full text

Creating a "city of art" : evaluating Singapore's vision of becoming a renaissance city by Lee, Wai Kin, 1975-

Get full text

The effect of graphene and graphene oxide induced reactive oxygen species on polycaprolactone scaffolds for bone cancer applications by Hou, Yanhao, Wang, Weiguang, Bartolo, Paulo

“…Polycaprolactone (PCL)-based scaffolds play an important role in bone regeneration, serving as a physical substrate to fill the defect site, recruiting cells, and promoting cell proliferation and differentiation, ultimately leading to the regeneration of the bone tissue without multiple surgical applications. …”
Get full text

Effects of electromagnetic field on proliferation, differentiation, and mineralization of MC3T3 cells by Teoh, Swee-Hin, Suryani, Luvita, Too, Jian Hui, Hassanbhai, Ammar Mansoor, Wen, Feng, Lin, Daryl Jimian, Yu, Na

“…This research provides insight and foundation to clinical application of noninvasive therapy using PEMF to improve bone regeneration.…”
Get full text
Get full text

Efficient Hydroxyapatite Extraction from Salmon Bone Waste: An Improved Lab-Scaled Physico-Chemico-Biological Process by Muñoz, Francisco, Haidar, Ziyad S., Puigdollers, Andreu, Guerra, Ignacio, Padilla, María Cristina, Ortega, Nicole, Balcells, Mercedes, García, María José

“…Salmon aquaculture generates significant volumes of waste, offering a sustainable opportunity for biomaterial production, particularly in osteo-conduction/-induction, and de novo clinical/surgical bone regeneration. Henceforth, this study explores re-purposing salmon waste through a standardized pre-treatment process that minimizes the biological <i>waste</i> content, followed by a treatment stage to remove proteins, lipids, and other compounds, resulting in a mineral-rich substrate. …”
Get full text

Contrasting effects of vasculogenic induction upon biaxial bioreactor stimulation of mesenchymal stem cells and endothelial progenitor cells cocultures in three-dimensional scaffol... by Chan, Jerry Kok Yen, Liu, Yuchun, Teoh, Swee-Hin, Chong, Mark S. K., Yeow, Chen-Hua, Kamm, Roger D., Choolani, Mahesh

“…Clinical translation of bone tissue engineering approaches for fracture repair has been hampered by inadequate vascularization required for maintaining cell survival, skeletal regeneration, and remodeling. …”
Get full text
Get full text

Synergistic effect of ultrasound and reinforced electrical environment by bioinspired periosteum for enhanced osteogenesis via immunomodulation of macrophage polarization through P... by Jiang, Ting, Yu, Fei, Zhou, Yuqi, Li, Ruomei, Zheng, Mengting, Jiang, Yangyang, Li, Zhenxia, Pan, Jun, Ouyang, Ningjuan

“…The periosteum plays a vital role in repairing bone defects. Researchers have demonstrated the existence of electrical potential in the periosteum and native bone, indicating that electrical signals are essential for functional bone regeneration. …”
Get full text

Optimising high porosity 3D scaffold by wet electrospinning by Ong, Su Ming

“…Micro fibrous scaffolds can be considered as a possible solution to tackle this problem and facilitate bone regeneration. The major components of bone tissue engineering consist of the scaffold, cells, and growth factors. …”
Get full text