A bilayer swellable drug-eluting ureteric stent : localized drug delivery to treat urothelial diseases by Lim, Wei Shan, Chen, Kenneth, Chong, Tsung Wen, Xiong, Gordon Minru, Birch, William R., Pan, Jisheng, Lee, Bae Hoon, Er, Pei Shan, Salvekar, Abhijit Vijay, Venkatraman, Subbu S., Huang, Yingying

“…On deployment, the device swells to co-apt with the ureteric wall and ensure drug availability to these tissues. …”
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Collection and analysis on data from Drugs.com by Aw, Teng Teng

“…In this report, Scrapy, is a web scraper, which will be used to extract data from Drugs.com. Scrapy is a framework, done in Python and the outputs will be saved in JSON files. …”
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Nanosized silica particles for chiral drug separation by Tan, Timothy Thatt Yang.

“…The current work addresses the urgent need of novel stationary phases for rapid enantionseparation, and it complements and supports the projects by the PI in the synthesis and application of nanoparticles for achiral and chiral drug separation. The emphasis of this work lies on nanoparticle synthesis and functionalization. …”
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Layer-by-layer assembled micro and nano carriers for drug delivery applications by Mutukumaraswamy Shaillender

“…In nano- or microparticulate drug delivery, both control of the drug release and interaction of the particles with the cellular environment are critical attributes. …”
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Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes by Low, Jianrong L., Gehring, Adam J., Kranz, David M., Grotenbreg, Gijsbert M., Yau, Yin Hoe, Shochat, Susana Geifman, Bertoletti, Antonio, Naidoo, Anneta, Yeo, Gladys, Ho, Zi Zong

“…Various protein scaffolds have been designed to recapitulate the specific recognition of presented antigens with the aim to be exploited both diagnostically (e.g. to visualize cells exposed to infectious agents or cellular transformation) and therapeutically (e.g. for the delivery of drugs to compromised cells). In line with this, we report the construction of a soluble tetrameric form of an αβ T cell receptor (TCR) specific for the HBV epitope Env183–191 restricted by HLA-A*02:01, and compare its avidity and fine-specificity with a TCR-like monoclonal antibody generated against the same HLA target. …”
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A bilayer swellable drug-eluting stent for the treatment of fibrosis-induced ureteral stricture recurrence by Lim, Wei Shan

“…The first layer is needed for sustained release of drug while the second layer is required for close contact with urothelial wall. …”
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Roughness-Controlled Self-Assembly of Mannitol/LB Agar Microparticles by Polymorphic Transformation for Pulmonary Drug Delivery by Zhang, Fengying, Ngoc, Nguyen Thi Quynh, Tay, Bao Hui, Mendyk, Aleksander, Shao, Yu-Hsuan, Lau, Raymond

“…SEM images coupled with image analysis software reveal that different surface morphology of the microparticles have different drug adhesion mechanisms. Comparison of ACI results and image analysis of SEM images shows that an increase in the particle surface roughness can increase the fine particle fractions (FPFs) using the rod-covered mannitol microparticles as drug carriers. …”
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Characterization and evaluation of bilayer coating for enhanced localization and sustained drug delivery for fibrosis-induced ureteral stricture by Chin, Jia Wen

“…The usage of a bilayer coating, consisting of a hydrogel layer and a drug-loaded polymer layer, allows for direct contact with the ureter walls upon swelling and drug delivery through the urothelium. …”
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Cationic glycosylated block co-β-peptide acts on the cell wall of Gram-positive bacteria as anti-biofilm agents by Zhang, Kaixi, Raju, Cheerlavancha, Zhong, Wenbin, Pethe, Kevin, Gründling, Angelika, Chan-Park, Mary B.

“…In addition to the emergence of resistance to last resort drugs, bacteria escape antibiotics killing by forming complex biofilms. …”
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Increasing antibiotic activity by rapid bioorthogonal conjugation of drug to resistant bacteria using an upconverted light-activated photocatalyst by Du, Quanchao, Wu, Xiangyang, Bi, Wuguo, Xing, Bengang, Yeow, Edwin Kok Lee

“…We demonstrate that the mode of action is due to increased inhibition of peptidoglycan cell wall biosynthesis. The findings in this study demonstrate that on-demand NIR-light activated bioorthogonal conjugation of Van to microbes is a viable alternative treatment in combating drug-resistant bacteria.…”
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Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY) by Karadzas, M

“…These screens reveal antifungal drug targets, transporters responsible for drug uptake or efflux, as well as metabolic, signalling and trafficking pathways affecting antifungal susceptibility. …”

AI is a viable alternative to high throughput screening: a 318-target study by Wallach, Izhar, Bernard, Denzil, Nguyen, Kong, Ho, Gregory, Morrison, Adrian, Stecula, Adrian, Rosnik, Andreana, O’Sullivan, Ann Marie, Davtyan, Aram, Samudio, Ben, Thomas, Bill, Worley, Brad, Butler, Brittany, Laggner, Christian, Thayer, Desiree, Moharreri, Ehsan, Friedland, Greg, Truong, Ha, van den Bedem, Henry, Ng, Ho Leung, Stafford, Kate, Sarangapani, Krishna, Giesler, Kyle, Ngo, Lien, Mysinger, Michael, Ahmed, Mostafa, Anthis, Nicholas J., Henriksen, Niel, Gniewek, Pawel, Eckert, Sam, de Oliveira, Saulo, Suterwala, Shabbir, PrasadPrasad, Srimukh Veccham Krishna, Shek, Stefani, Contreras, Stephanie, Hare, Stephanie, Palazzo, Teresa, O’Brien, Terrence E., Van Grack, Tessa, Williams, Tiffany, Chern, Ting-Rong, Kenyon, Victor, Lee, Andreia H., Cann, Andrew B., Bergman, Bastiaan, Anderson, Brandon M., Cox, Bryan D., Warrington, Jeffrey M., Sorenson, Jon M., Goldenberg, Joshua M., Young, Matthew A., DeHaan, Nicholas, Pemberton, Ryan P., Schroedl, Stefan, Abramyan, Tigran M., Gupta, Tushita, Mysore, Venkatesh, Presser, Adam G., Ferrando, Adolfo A., Andricopulo, Adriano D., Ghosh, Agnidipta, Ayachi, Aicha Gharbi, Mushtaq, Aisha, Shaqra, Ala M., Toh, Alan Kie Leong, Smrcka, Alan V., Ciccia, Alberto, de Oliveira, Aldo Sena, Sverzhinsky, Aleksandr, de Sousa, Alessandra Mara, Agoulnik, Alexander I., Kushnir, Alexander, Freiberg, Alexander N., Statsyuk, Alexander V., Gingras, Alexandre R., Degterev, Alexei, Tomilov, Alexey, Vrielink, Alice, Garaeva, Alisa A., Bryant-Friedrich, Amanda, Caflisch, Amedeo, Patel, Amit K., Rangarajan, Amith Vikram, Matheeussen, An, Battistoni, Andrea, Caporali, Andrea, Chini, Andrea, Ilari, Andrea, Mattevi, Andrea, Foote, Andrea Talbot, Trabocchi, Andrea, Stahl, Andreas, Herr, Andrew B., Berti, Andrew, Freywald, Andrew, Reidenbach, Andrew G., Lam, Andrew, Cuddihy, Andrew R., White, Andrew, Taglialatela, Angelo

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Overcoming endurance issue : UAV-enabled communications with proactive caching by Xu, Xiaoli, Zeng, Yong, Guan, Yong Liang, Zhang, Rui

“…Specifically, we focus on content-centric communication systems, where a UAV is dispatched to serve a group of ground nodes (GNs) with random and asynchronous requests for files drawn from a given set. With the proposed scheme, at the beginning of each operation period, the UAV pro-actively transmits the files to a subset of selected GNs that cooperatively cache all the files. …”
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Development of multimedia educational software by Saw, Thant Lwin Tun.

“…While this educational software was developed by using Visual Basic programming, graphical presentations and 3D images were drawn by using Autodesk Revit and were exported to Visual Basic as image files for creation of animations.…”
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Sawmill: From Logs to Causal Diagnosis of Large Systems by Markakis, Markos, Chen, An Bo, Youngmann, Brit, Gao, Trinity, Zhang, Ziyu, Shahout, Rana, Chen, Peter Baile, Liu, Chunwei, Sabek, Ibrahim, Cafarella, Michael

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21W.775 Writing about Nature and Environmental Issues, Spring 2006 by Lioi, Anthony

“…Authors include Henry Thoreau, Loren Eiseley, Annie Dillard, Chet Raymo, Sue Hubbel, Rachel Carson, Bill McKibben, and Terry Tempest Williams.…”
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An innovative design of household civil defence shelters by Khong, Zhi Cong.

“…Another is a CDS with walls that are 40 percent leaner than the existing design. …”
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Comparative study on design of braced excavation systems by Toh, Yan Ting

“…From this study, the following findings are drawn: The Hardening Soil and the Hardening Soil with small-strain stiffness models generate conservative settlement profiles compared to the Mohr-Coulomb model; Combination 1 provides a conservative estimation of the wall bending moments; Upper strut forces are more conservative using DA1 Combination 1 while bottom strut forces are more conservative using DA1 Combination 2 Scheme 1; Scheme 2 gives a large bending moment than Scheme 1; The Mohr-Coulomb model, generally, gives a smaller maximum wall bending moment than the Hardening Soil model; findings from sheet pile excavation deviate from those from diaphragm wall excavations; and lastly, consideration of factored E50/cu ratio produces similar strut forces and bending moments compared to unfactored E50/cu values.…”
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Methods for the Study of Galactofuranose in Mycobacteria by Taylor, Katherine I.

“…Second, we leveraged the rapidly expanding set of biosynthetic probes of the mycobacterial cell wall to rapidly characterize intracellular distances between distinct layers of the cell wall in Mycobacterium tuberculosis model organisms Corynebacterium glutamicum and Mycobacterium smegmatis using fluorescence resonance energy transfer. …”
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Cloud Spark Cluster to analyse English prescription big data for NHS intelligence by Fernando, Sandra, Sowinski-Mydlarz, Viktor, Virdee, Bal Singh

“…Even though Spark is a complete in-memory framework, although limited with its big data platforms facilities compared to Hadoop, Spark analytics engine with Ha-doop distributed file system gives better throughput than Hadoop alone. …”
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