Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes by Low, Jianrong L., Gehring, Adam J., Kranz, David M., Grotenbreg, Gijsbert M., Yau, Yin Hoe, Shochat, Susana Geifman, Bertoletti, Antonio, Naidoo, Anneta, Yeo, Gladys, Ho, Zi Zong

“…Various protein scaffolds have been designed to recapitulate the specific recognition of presented antigens with the aim to be exploited both diagnostically (e.g. to visualize cells exposed to infectious agents or cellular transformation) and therapeutically (e.g. for the delivery of drugs to compromised cells). In line with this, we report the construction of a soluble tetrameric form of an αβ T cell receptor (TCR) specific for the HBV epitope Env183–191 restricted by HLA-A*02:01, and compare its avidity and fine-specificity with a TCR-like monoclonal antibody generated against the same HLA target. …”
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Bad Mexican : portrayal of corruption and the drug trade in Man on Fire, Traffic, and La Ley de Herodes. by Goh, Dianne.

“…By victimizing the United States and demonizing Mexico, Hollywood films such as Traffic and Man on Fire create stereotypes of Mexicans based on the drug trade and corruption in Mexico so the United States can define its identity and become Mexico’s saviour. …”
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A bilayer swellable drug-eluting ureteric stent : localized drug delivery to treat urothelial diseases by Lim, Wei Shan, Chen, Kenneth, Chong, Tsung Wen, Xiong, Gordon Minru, Birch, William R., Pan, Jisheng, Lee, Bae Hoon, Er, Pei Shan, Salvekar, Abhijit Vijay, Venkatraman, Subbu S., Huang, Yingying

“…On deployment, the device swells to co-apt with the ureteric wall and ensure drug availability to these tissues. …”
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Nanosized silica particles for chiral drug separation by Tan, Timothy Thatt Yang.

“…The current work addresses the urgent need of novel stationary phases for rapid enantionseparation, and it complements and supports the projects by the PI in the synthesis and application of nanoparticles for achiral and chiral drug separation. The emphasis of this work lies on nanoparticle synthesis and functionalization. …”
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‘Token’ augmented reality visual effects film by Koh, Iris Xuan En

“…‘Token’ is a 4 minutes live-action with augmented reality visual effects film, exploring the techniques of green screen shooting and keying, 2D and 3D compositing, particle simulation, and 2D and 3D animation. …”
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Layer-by-layer assembled micro and nano carriers for drug delivery applications by Mutukumaraswamy Shaillender

“…In nano- or microparticulate drug delivery, both control of the drug release and interaction of the particles with the cellular environment are critical attributes. …”
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Review of audience gratification with Chinese online film festivals by Yang, Yening, Ahmad Ghazali, Akmar Hayati, Shari, Sharil Nizam

“…Against this backdrop, online film festivals have emerged as a new subject of film festival research. …”
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The influence of additives on the delivery of paclitaxel from bioresorbable PLGA films by Huang, Charlotte Liwen.

“…The study of the influences of additives on the drug delivery characteristics from PLGA thin films as a coating on angioplasty balloons was reported in this thesis. …”
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Formulation and in-vitro release study of drug loaded liposomes for treating dry eye disease by Chua, Yan Ni

“…Thin film hydration method technology is employed to fabricate the liposomes and to encapsulate the drug within its hydrophobic bilayer of the liposomes. …”
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Tantalum based amorphous thin films as copper diffusion barrier by Yan, Hua

“…Guidelines of developing reliable Cu diffusion barrier are drawn base on this study.…”
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A bilayer swellable drug-eluting stent for the treatment of fibrosis-induced ureteral stricture recurrence by Lim, Wei Shan

“…The first layer is needed for sustained release of drug while the second layer is required for close contact with urothelial wall. …”
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Roughness-Controlled Self-Assembly of Mannitol/LB Agar Microparticles by Polymorphic Transformation for Pulmonary Drug Delivery by Zhang, Fengying, Ngoc, Nguyen Thi Quynh, Tay, Bao Hui, Mendyk, Aleksander, Shao, Yu-Hsuan, Lau, Raymond

“…SEM images coupled with image analysis software reveal that different surface morphology of the microparticles have different drug adhesion mechanisms. Comparison of ACI results and image analysis of SEM images shows that an increase in the particle surface roughness can increase the fine particle fractions (FPFs) using the rod-covered mannitol microparticles as drug carriers. …”
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Characterization and evaluation of bilayer coating for enhanced localization and sustained drug delivery for fibrosis-induced ureteral stricture by Chin, Jia Wen

“…The usage of a bilayer coating, consisting of a hydrogel layer and a drug-loaded polymer layer, allows for direct contact with the ureter walls upon swelling and drug delivery through the urothelium. …”
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Surface modification of smooth poly (L-lactic acid) films for gelatin immobilization by Li, Hai, Xia, Yun, Wu, Jumiati, He, Qiyuan, Zhou, Xiaozhu, Lu, Gang, Shang, Lei, Boey, Freddy Yin Chiang, Venkatraman, Subbu S., Zhang, Hua

“…Poly(l-lactic acid) (PLLA) is widely used in drug delivery and medical implants. Surface modification of PLLA with functional groups to immobilize gelatin or other extracellular matrix proteins is commonly used to improve its cellular affinity. …”
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Cationic glycosylated block co-β-peptide acts on the cell wall of Gram-positive bacteria as anti-biofilm agents by Zhang, Kaixi, Raju, Cheerlavancha, Zhong, Wenbin, Pethe, Kevin, Gründling, Angelika, Chan-Park, Mary B.

“…In addition to the emergence of resistance to last resort drugs, bacteria escape antibiotics killing by forming complex biofilms. …”
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Increasing antibiotic activity by rapid bioorthogonal conjugation of drug to resistant bacteria using an upconverted light-activated photocatalyst by Du, Quanchao, Wu, Xiangyang, Bi, Wuguo, Xing, Bengang, Yeow, Edwin Kok Lee

“…We demonstrate that the mode of action is due to increased inhibition of peptidoglycan cell wall biosynthesis. The findings in this study demonstrate that on-demand NIR-light activated bioorthogonal conjugation of Van to microbes is a viable alternative treatment in combating drug-resistant bacteria.…”
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Janus particle preparation through UV-induced partial photodegradation of spin-coated particle films by Tan, Jasmine Si Jia, Wong, Chong Hui, Chen, Zhong

“…Photocatalytic titanium dioxide particles prefunctionalized with a surface coating were assembled as particle films via spin-coating on a substrate. The particle films were placed directly under an ultraviolet light source, which induced the photodegradation of the surface coating only on the particle surfaces exposed to the light. …”
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Enabling high performance n-type metal oxide semiconductors at low temperatures for thin film transistors by Tiwari, Nidhi, Nirmal, Amoolya, Kulkarni, Mohit Rameshchandra, John, Rohit Abraham, Mathews, Nripan

“…Amorphous oxide semiconductors have drawn considerable attention as a replacement for ubiquitous silicon based technologies. …”
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Effects of woven fabric embedment on thin film composite membranes for osmotically driven membrane processes (ODMPs) by Teo, Shino Yu Qin

“…Osmotically driven membrane processes (ODMPs) have drawn a lot of attention in recent years due to their potential applications in water purification, desalination and energy generation. …”
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Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY) by Karadzas, M

“…These screens reveal antifungal drug targets, transporters responsible for drug uptake or efflux, as well as metabolic, signalling and trafficking pathways affecting antifungal susceptibility. …”