Is Africa’s growing public debt really crowding out private investment? by Mulangu, Francis

“…Total external debt for sub-Saharan Africa jumped nearly 150% to $583 billion in 2018, from $236 billion 10 years earlier according to the World Bank. Many now worry the debt burden is unsustainable. …”
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Direct and indirect effects of fire on microbial communities in a pyrodiverse dry-sclerophyll forest by Bowd, Elle J., Egidi, Eleonora, Lindenmayer, David B., Wardle, David A., Kardol, Paul, Cary, Geoffrey J., Foster, Claire

“…Fire is one of the predominant drivers of the structural and functional dynamics of forest ecosystems. In recent years, novel fire regimes have posed a major challenge to the management of pyrodiverse forests. …”
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Fabrication of high-performance thin-film composite and nanochannel-enabled next-generation membranes for water desalination by Lim, Yu Jie

“…Water reuse and seawater desalination have evolved into alternative water sources in the last 40 years in response to the increasing freshwater scarcity. …”
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COVID-19 and bilingual children's home language environment: digital media, socioeconomic status, and language status by Sun, He, Tan, Justina, Chen, Wenli

“…Survey data from 162 parents of English-Mandarin bilingual preschoolers (3 to 6 years old) were used to explore the two research questions. …”
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Outcome assessment for out-of-hospital cardiac arrest patients in Singapore and Japan with initial shockable rhythm by Okada, Yohei, Shahidah, Nur, Ng, Yih Yng, Chia, Michael Y. C., Gan, Han Nee, Leong, Benjamin S. H., Mao, Desmond R., Ng, Wei Ming, Irisawa, Taro, Yamada, Tomoki, Nishimura, Tetsuro, Kiguchi, Takeyuki, Kishimoto, Masafumi, Matsuyama, Tasuku, Nishioka, Norihiro, Kiyohara, Kosuke, Kitamura, Tetsuhisa, Iwami, Taku, Ong, Marcus Eng Hock

“…This study included adult (18–74 years) OHCA patients with initial shockable rhythm. …”
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Insights from coral microatolls into sea-level variability and subduction zone behavior by Sarkawi, Gina Muthia

“…Two generations of fossil coral microatolls were analyzed, one from 1000 calibrated years before present and the younger fossil generation from the 19th century. …”
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Electronic cigarette use and chest pain in US adults: evidence from the PATH study by Behrooz, Leili, Xie, Wubin, Goghari, Aboli, Robertson, Rosemarie, Bhatnagar, Aruni, Stokes, Andrew, Hamburg, Naomi M.

“…Presence of established cardiovascular disease was examined at wave 4, and participants aged >40 years were asked about chest pain during wave 5. …”
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The association of sleep duration with the risk of chronic kidney disease: a systematic review and meta-analysis by Koh, Jin Hean, Yeo, Brian Sheng Yep, Tan, Timothy Wei En, See, Mark Yong Siang, Ng, Adele Chin Wei, Loh, Shaun Ray Han, Gooley, Joshua, Tan, Chieh Suai, Toh, Song Tar

“…In total, 42 studies (2 613 971 patients) with a mean age of 43.55 ± 14.01 years were included in the meta-analysis. Compared with a reference range of 7 to 8 hours of sleep, short sleep durations of ≤4 hours (RR 1.41, 95% CI: 1.16 to 1.71, P < 0.01), ≤5 hours (RR 1.46, 95% CI: 1.22 to 1.76, P < 0.01), ≤6 hours (RR 1.18, 95% CI: 1.09 to 1.29, P < 0.01), and ≤7 hours (RR 1.19, 95% CI: 1.12 to 1.28, P < 0.01) were significantly associated with an increased risk of incident chronic kidney disease. …”
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BSACI guidance for the implementation of Palforzia® peanut oral immunotherapy in the United Kingdom: a Delphi consensus study by Marrs, Tom, Patel, Nandinee, Burrell, Sarah, Rampersad, Anjali, Minshall, Eleanor, Leech, Susan, Chandratilleke, Dinusha, Dempsey, Justine, Ludman, Sian, Roberts, Graham, Michaelis, Louise Jane, Brough, Helen A., Karanam, Surendra, Batt, Rebecca, Moulsdale, Phoebe, Steifel, Gary, Tiwana, Kiran, Smith, Helen, Knight, Katherine, Vazquez-Ortiz, Marta, Vyas, Deepan, Turner, Paul J., Makwana, Nick

“…These guidance statements will be adapted in the coming years as more evidence is published and as the international experience of peanut immunotherapy evolves.…”
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闽西北农村环境污染对闽江水质影响的研究 = Effect of agricultural pollutants in north-west Fujian Province on Ming Jiang water quality by 游诗祥 You, Shixiang, 黄月珍 Huang, Yuezhen, 吴成城 Wu, Chengcheng

“…In this paper, clean the county as the representative from the rural farming, aquaculture and living pollution analysis of three aspects of environmental pollution in rural northwestern Fujian, the main pollutants that the rural northwest of Fujian is COD, total phosphorus, total nitrogen three categories, and through infiltration of surface runoff or underground into the Minjiang River; the same time, exceeding the water quality of Minjiang River over the years and found that the number exceeded 51%, 57% of types of pollutants and pollution in rural areas northwest of Fujian.…”
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Infections diagnosed in children and young people screened for malaria in UK emergency departments: a retrospective multi-centre study by Bird, C, Hayward, GN, Turner, PJ, Wasala, D, Merrick, V, Lyttle, MD, Mullen, N, Fanshawe, TR

“…</p> <br> <p><strong>Methods:</strong> This is a retrospective, multi-centre, observational study nested in a diagnostic accuracy study for malaria rapid diagnostic tests. Any CYP less than 16 years presenting to a participating ED with a history of fever and travel to a malaria-endemic area between 1 January 2016 and 31 December 2017 and who had a malaria screen as a part of standard care were included. …”

Essays on the market for corporate bonds by Levonmaa, A

“…This study uses a large dataset of corporate bond transactions from the TRACE database for the US corporate bond market, combined with credit rating changes from Fitch, Moody's and Standard and Poor's (S&amp;P), to analyse over 22,000 bonds, coupled with approximately 28,400 rating events over nearly six years. The results show that the bond market responds to news on credit quality asymmetrically: credit rating downgrades, representing bad news for bond holders, produce the strongest response in returns, whilst upgrades do not generate a statistically significant increase in returns. …”

Early, very high-titre convalescent plasma therapy in clinically vulnerable individuals with mild COVID-19 (COVIC-19): protocol for a randomised, open-label trial by Desmarets, M, Hoffmann, S, Vauchy, C, Rijnders, BJA, Toussirot, E, Durrbach, A, Körper, S, Schrezenmeier, E, van der Schoot, CE, Harvala, H, Brunotte, G, Appl, T, Seifried, E, Tiberghien, P, Bradshaw, D, Roberts, DJ, Estcourt, LJ, Schrezenmeier, H

“…We will enrol patients in two cohorts of vulnerable patients [(1) elderly 70+ years, or younger with comorbidities; (2) immunocompromised patients]. …”

Using feminist methodologies to explore female genital mutilation/cutting and child marriage in low- and middle-income contexts by Jones, N, Pincock, K, Alheiwidi, S

“…Eliminating harmful practices, which are rooted in gender inequality and have myriad life-course consequences for those who experience them, has become a global priority in recent years. However, dominant conceptualizations of the drivers and consequences of child marriage and FGM/C often fail to adequately engage with or reflect adolescent girls' own nuanced experiences and perceptions. …”

Mechanistic insights into the HPF1/PARP1 complex by Zobel, FFH

“…While PARP1 was originally described to modify target substrates on glutamate and aspartate sites, it has become apparent in recent years that the presence of another protein, histone PARylation factor 1 (HPF1), switches its preference to serine target sites. …”

HLA-DQB1*05 subtypes and not DRB1*10:01 mediates risk in anti-IgLON5 disease by Yogeshwar, SM, Muñiz-Castrillo, S, Sabater, L, Peris-Sempere, V, Mallajosyula, V, Luo, G, Yan, H, Yu, E, Zhang, J, Lin, L, Fagundes Bueno, F, Ji, X, Picard, G, Rogemond, V, Pinto, AL, Heidbreder, A, Höftberger, R, Graus, F, Dalmau, J, Santamaria, J, Iranzo, A, Schreiner, B, Giannoccaro, MP, Liguori, R, Shimohata, T, Kimura, A, Ono, Y, Binks, S, Mariotto, S, Dinoto, A, Bonello, M, Hartmann, CJ, Tambasco, N, Nigro, P, Prüss, H, McKeon, A, Davis, MM, Irani, SR, Honnorat, J, Gaig, C, Finke, C, Mignot, E

“…This association was further reflected in an increasingly later age of onset across each genotype group, with a delay of up to 11 years, while HLA-DQ-dosage dependent effects were also suggested by reduced risk in the presence of non-predisposing DQ1 alleles. …”

Experiences, perceptions and ethical considerations of the malaria infection study in Thailand by Naemiratch, B, Kulpijit, N, Ruangkajorn, S, Day, NPJ, Prachumsri, J, Cheah, PY

“…However, due to cross-border movements over the past 5 years, reported malaria cases in Thailand have risen. …”

Prussian Blue analogue materials for magnetic and energy storage applications by Schart, M

“…Upon its discovery in the 18th century, Prussian Blue, the first synthetic pigment, gained fame for its intense colour. Over the years since, many multifunctional properties have been discovered in its analogue materials. …”

Self-supervised machine learning to characterise step counts from wrist-worn accelerometers in the UK Biobank by Small, SR, Chan, S, Walmsley, R, von Fritsch, L, Acquah, A, Mertes, G, Feakins, BG, Creagh, A, Strange, A, Matthews, CE, Clifton, DA, Price, AJ, Khalid, S, Bennett, D, Doherty, A

“…Our data indicate an inverse dose-response association, where taking 6,430-8,277 daily steps was associated with 37% [25-48%] and 28% [20-35%] lower risk of fatal CVD and all-cause mortality up to seven years later, compared to those taking fewer steps each day.…”

Validating the ratio of insulin like growth factor binding protein 4 to sex hormone binding globulin as a prognostic predictor of preterm birth in Viet Nam: a case-cohort study by Hirst, JE, Boniface, JJ, Le, DP, Polpitiya, AD, Fox, AC, Vu, TTK, Dang, TT, Fleischer, TC, Bui, NTH, Hickok, DE, Kearney, PE, Thwaites, G, Kennedy, SH, Kestelyn, E, Le, TQ

“…Optimal performance (AUC 0.74) was seen within 19-20 weeks’ gestation, for BMI &gt;21 kg/m2 and age 20-35 years. <p><strong> Conclusion</strong></p> We have validated a novel serum biomarker for PTB risk stratification in a very different setting to the original study. …”