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The yeast FIT2 homologs are necessary to maintain cellular proteostasis and membrane lipid homeostasis
Published 2022“…While LD biogenesis and basal endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) remain unaltered in ScFIT mutants, SCS3 was found to be essential for proper stress-induced UPR activation and for viability in the absence of the sole yeast UPR transducer IRE1 Owing to not having a functional UPR, cells with mutated SCS3 exhibited an accumulation of triacylglycerol within the ER along with aberrant LD morphology, suggesting that there is a UPR-dependent compensatory mechanism that acts to mitigate lack of SCS3 Additionally, SCS3 was necessary to maintain phospholipid homeostasis. …”
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Journal Article -
22
Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community
Published 2024“…Genome-scale metabolic models (GEMs) can facilitate metabolism-focused multi-omics integrative analysis. Since Yeast8, the yeast-GEM of Saccharomyces cerevisiae, published in 2019, has been continuously updated by the community. …”
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Journal Article -
23
One-Pass Learning via Bridging Orthogonal Gradient Descent and Recursive Least-Squares
Published 2025“…By doing so, we bridge two seemingly distinct algorithms in adaptive filtering and machine learning, namely the recursive least-squares (RLS) algorithm and orthogonal gradient descent (OGD). …”
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Thesis -
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Fast prototyping of neural network application
Published 2022“…To solve the problem of fast training and classification, hardware accelerator is proposed. …”
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Thesis-Master by Coursework -
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Fast numerical methods for image restoration
Published 2012“…The other one is graph cuts technique for fast solving higher order curvature based models. …”
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Thesis -
27
Marketing strategies of fast food chains
Published 2015“…The motivating force that spearheaded us to take on this project ts the inherent competitiveness of the fast food industry. We are more curious, rather than fascinated, by how the restaurants remain competitive despite the tense competition in the market. …”
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Final Year Project (FYP) -
28
Genetic, genomic and systems biology analysis of adaptive evolution of budding yeast to the deletion of essential genes
Published 2016“…However previous studies in budding yeast challenged this view by showing that mutants deleted of essential or non-essential genes are capable of accumulating compensatory mutations and resume viability, suggesting that essentiality is not an intrinsic gene property but depends on the cellular capacity to evolve. …”
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Research Report -
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Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY)
Published 2024Subjects:Thesis -
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Accurate and Fast Approximate Graph Mining at Scale
Published 2024“…We build ScaleGPM, an accurate and fast A-GPM system that removes the two obstacles. …”
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Thesis -
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Fast motion estimation algorithms for video coding
Published 2009“…Since many practical video applications (e.g., video conferencing) require real time processing of video data, fast and accurate motion estimation is crucial to the processing speed and reconstructed image quality.…”
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Thesis -
36
Trans-phonon effects in ultra-fast nanodevices
Published 2011“…We report a novel phenomenon in carbon nanotube based ultra-fast mechanical devices, the trans-phonon effect, which resembles the transonic effects in aerodynamics. …”
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Journal Article -
37
The effects of fasting on acute ischemic infarcts in the rat
Published 2024“…Inflammation is largely detrimental early in the acute phase of stroke but beneficial at more chronic stages. Fasting has been shown to reduce inflammation acutely. …”
Journal article -
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Optimal leak factor selection for the output-constrained leaky filtered-input least mean square algorithm
Published 2020“…The leaky filtered-input least mean square (LFxLMS) algorithm is widely used in active noise control applications to minimize the degradation of attenuation performance due to output saturation distortion. …”
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Journal Article -
39
Design implementation low energy fast fourier transform/inverse fast fourier transform (FFT/IFFT) processor based on asynchronous-logic
Published 2008“…The circuits designed herein span from microcells and macrocells to a complete 128-point radix-2 decimation-in-time Fast Fourier Transform/Inverse Fast Fourier Transform (FFT/IFFT) processor for energy-critical audio applications, including hearing aids. …”
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Thesis -
40
Fasting-induced torpor in mice: effects on sleep and behaviour
Published 2023“…Overall, this thesis provides novel insights into the characteristics, neurophysiology, and regulation of fasting-induced torpor in mice. Moreover, the data presented here highlight the potential for torpor to be a potential confound in research using fasting techniques if not adequately controlled for.…”
Thesis