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1601
An observational study of the prevalence of metabolic syndrome in treatment-experienced people living with HIV in Singapore
Published 2021“…Of all the 2,231 individuals, 68.8% had at least one component of MetS. The overall prevalence of MetS was 23.6% (95% confidence interval 21.9%–25.4%). …”
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Journal Article -
1602
Analysis of influence and its applications in social advertising
Published 2022“…Our method generates only the samples spreading influence beyond the source with at least one 2-hop live path. The samples generated by our 2-hop+ method can yield the random variable to estimate with tighter ranges and better concentration bounds can be applied to obtain an approximation of the random variable with a theoretically tighter threshold requiring less samples. …”
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Thesis-Doctor of Philosophy -
1603
Rationalisation of antifungal properties of α-helical pore-forming peptide, mastoparan B
Published 2022“…Among the four peptides, mastoparan B (MB) displayed potent antifungal activity, whereas cecropin A was the least potent. We show that MB susceptibility of phylogenetically distant non-candida albicans can vary and be described by different intrinsic physicochemical parameters of pore-forming α-helical peptides. …”
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Journal Article -
1604
Molecular recognition in protein-DNA assemblies
Published 2009“…Extensive adduct formation observed at the centre of the NCP suggests that this region of the nucleosome, known to be least accessible to protein factors, may provide a favorable target for the design of improved platinum anticancer drugs.In addition to platinum drug site selectivity studies, we engaged in biophysical and biochemical studies revealing functional aspects of chromatin-drug interactions that are shedding light on new possibilities for anticancer agent development. …”
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Research Report -
1605
Evaluation of the safety and immunogenicity of different COVID-19 vaccine combinations in healthy individuals: study protocol for a randomized, subject-blinded, controlled phase 3...
Published 2023“…More than 90% of the Singapore population has received at least one dose of a COVID-19 vaccine as of December 2021. …”
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Journal Article -
1606
Joint client-and-sample selection for federated learning via bi-level optimization
Published 2024“…Extensive experiments comparison against eight state-of-the-art baselines on six real-world datasets in the presence of data noise and heterogeneity shows that FedMW-CSS achieves up to 28.5% higher test accuracy, while saving communication and computation costs by at least 49.3% and 1.2%, respectively.…”
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Journal Article -
1607
High-efficiency magnetophoretic labelling of adoptively-transferred T cells for longitudinal in vivo magnetic particle imaging
Published 2024“…Results: Labelling efficiency was improved more than 10-fold over prior studies enabling longer-term tracking for at least two weeks in vivo of the labelled immune cells and their biodistribution relative to the tumour. …”
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Journal Article -
1608
Synthesis and characterization of reduced graphene oxide-based composites
Published 2012“…In addition, the Fe3O4-Pt/rGO composite can catalyze the reduction of methylene blue and be recycled within 1 min by applying an external magnetic field for at least 16 times.…”
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Thesis -
1609
Electric-field control of magnetism in multiferroic composites
Published 2015“…Multiferroic materials have at least two of the ferroic properties, namely ferroelectricity, ferro (anitferro) magnetism and ferroelasticity.The term usually refers to materials that possess both ferroelectric and magnetic orders. …”
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Thesis -
1610
Selective lighting up of epiberberine alkaloid fluorescence by fluorophore-switching aptamer and stoichiometric targeting of human telomeric DNA G-quadruplex multimer
Published 2015“…The binding affinity of EPI to TA[Q] (Kd = 37 nM) is at least 20 times tighter than those of the other alkaloids. …”
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Journal Article -
1611
Upper mantle rheology from GRACE and GPS postseismic deformation after the 2004 Sumatra-Andaman earthquake
Published 2012“…Mantle rheology is one of the essential, yet least understood, material properties of our planet, controlling the dynamic processes inside the Earth's mantle and the Earth's response to various forces. …”
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Journal Article -
1612
Role of the collagen receptor DDR1 in epithelial morphogenesis and polarisation
Published 2017“…</p> <p>Overall, this study suggests that DDR1 signalling contributes to epithelial polarisation and morphogenesis in a manner involving regulation of cytoskeletal organisation, at least partly through regulation of ROCK activity.…”
Thesis -
1613
Consensus on current management of endometriosis
Published 2013“…Several guidelines have been developed by a number of national and international bodies, yet areas of controversy and uncertainty remain, not least due to a paucity of firm evidence. </p> <p><strong>Study design, size, duration:</strong> A consensus meeting, in conjunction with a pre- and post-meeting process, was undertaken. …”
Journal article -
1614
Internet tool to support self-assessment and self-swabbing of sore throat: development and feasibility study
Published 2023“…A web-based tool that helps people assess their sore throat, through the use of clinical prediction rules, taking throat swabs or saliva samples, and taking throat photographs, has the potential to improve self-management and help identify those who are the most and least likely to benefit from antibiotics. <br><strong> Objective:<br></strong> We aimed to develop a web-based tool to help patients and parents or carers self-assess sore throat symptoms and take throat photographs, swabs, and saliva samples for diagnostic testing. …”
Journal article -
1615
Antihyperlipidemic and hepatoprotective effect of Zingiber cassumunar Rhizome extract in high-fat diet-induced hyperlipidemic rats: the role of antioxidant activity
Published 2023“…Data of the study were presented as mean ± SD and analyzed by using one way analysis of variance (ANOVA) followed by Least Significant Difference (LSD) test for multiple comparisons. …”
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Article -
1616
Effects of carbon to nitrogen ratio and organic loading rate on biogas methane production from anaerobic digestion of food waste
Published 2014“…The feedstock with C/N=30 had the least foaming tendency with foaming volume of 10% at OLR of 7.5 g VS/Ld.…”
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Thesis -
1617
Designing for Connection with Inner Processes
Published 2024“…Today's online ecosystems offer us many new ways to communicate personal stories, often through fast-paced, reactive channels, but few if any technologies enable us to share what I posit to be a crucial component of how we implicitly understand each other: our inner processes, e.g., how we form our values and identities, navigate unspoken tensions in a community, or feel that something resonates with us. …”
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Thesis -
1618
Efficient stochastic optimization algorithms for performance-based system design with application to structural control system design for floating offshore wind turbines
Published 2019“…The dynamic response of the coupled controller and floating wind turbine system is obtained by a high-fidelity nonlinear simulator FAST-SC (Fatigue, Aerodynamics, Structures and Turbulence, Structural Control). …”
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Thesis -
1619
Ferroelectric-field accelerated charge transfer in 2D CuInP₂S₆ heterostructure for enhanced photocatalytic H₂ evolution
Published 2022“…The development of ferroelectric photocatalytic materials with polarization electric field is a key approach to realize the spatial separation and fast transfer of charge carriers in visible-light-driven H2 evolution. …”
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Journal Article -
1620
Lithium-doped two-dimensional perovskite scintillator for wide-range radiation detection
Published 2023“…Our 1:1 Li-doped (PEA)2PbBr4 demonstrates a fast decay time of 11 ns (80%), a clear photopeak with an energy resolution of 12.4%, and a scintillation yield of 11,000 photons per MeV under 662 keV gamma-ray radiation. …”
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Journal Article