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1921
Improving the diagnostic yield of whole genome sequencing: neurodevelopmental and epilepsy disorders
Published 2023“…Following the initial report that described KMT2E as a neurodevelopmental disorder-causing gene, a new syndrome called O'Donnell-Luria-Rodan-Rodan syndrome (ODLURO) has been recognised, and the gene has received approval for panel testing. …”
Thesis -
1922
(宋代「武夷棹歌」中的地景空間與文化意蘊) = Landscape and culture in the Wu-yi Zhao Ge (Wu-yi boat song) of Song dynasty
Published 2014“…In 1183, Neo-Confucianist Zhu Xi (1130-1200) built a villa in Wu-yi mountain and called it “Wu-yi Jing She”. He conducted lectures and provided enriching thinking to his followers for more than ten years, which has subsequently benefitted more than two hundred students. …”
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Journal Article -
1923
Tracking and detecting objects in image sequence
Published 2016“…First, foreground regions are obtained by using background subtraction on depth data. Then, a so-called “split-merge” approach is proposed to over-segment a foreground region into subregions and then cluster them into a number of object regions by using the proposed boundary based similarity metric. …”
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Thesis -
1924
Exploiting LoRaWAN for efficient and resilient IoT networks
Published 2020“…To advance the network architecture design, this thesis leverages on the LoRaWAN to form one-hop out-of-band control planes called LoRaCP. Several characteristics of LoRaWAN such as downlink-uplink asymmetry and primitive ALOHA media access control need to be dealt with to achieve high efficiency and good resilience. …”
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Thesis-Doctor of Philosophy -
1925
Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo...
Published 2014“…Generally, Gram-negative bacterial pathogens have additional outer membranes mainly composed of highly conserved and unique lipopolysaccharide (LPS) molecules, which serve as permeability barriers to prevent the cell bodies from toxic antimicrobial molecules1-2 including many photosensitizers, which have been successfully used in photoinactivation of Gram-positive strains.3-4 Furthermore, LPS, a potent inducer to human innate immune systems, hence called endotoxin, is now primarily responsible for sepsis associated with the infections of Gram-negative pethogens.5-6 Therefore, the most promising strategy is use of LPS neutralizing peptide as the binding ligand to deliver antibacterial agents meanwhile minimize the side effects.7 The first objective of the research in part I is the design and synthesis of photosensitizer-peptide conjugates for multivalent targeted cellular imaging and photodynamic inactivation (PDI) against Gram-negative bacterial strains. …”
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Thesis -
1926
Surface engineering to manipulate solar energy for thermal management
Published 2023“…Accordingly, an optically modified, high water content hydrogel matrix was designed as a passive radiative cooler at daytime, which is called metagel. The metagel radiative cooler utilizes both radiative and evaporative cooling processes within an individual composite, while also exhibiting strong visible-NIR (near infrared) Mie scattering minimizes the incident solar energy, keeping surface temperature low. …”
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Thesis-Doctor of Philosophy