Continuous, high-throughput production of artemisinin-loaded supramolecular cochleates using simple off-the-shelf flow focusing device by Shuddhodana, Wong, Kathy Pooi Wen, Judeh, Zaher

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Optimising expression and purification of Dengue soluble E protein by Poh, Nina Yong Xin

“…It offers insights into viral-host immune interactions. The full-length E protein is essential for vaccine design. …”
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Identification and antimicrobial susceptibility of enterococcal species isolated from cats exposed to different antibiotics by Mohd Amin, Nor Azimah

“…Two multi drug resistant (MDR) enterococci and two extensively drug resistant (XDR) enterococci were detected in this present study.…”
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MicroRNAs in tissue engineering & regenerative medicine by Chew, Sing Yian

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Synthesis of chiral sulfinate esters by asymmetric condensation by Zhang, Xin, Ang, Esther Cai Xia, Yang, Ziqi, Kee, Choon Wee, Tan, Choon-Hong

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Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya by Osoti, V, Wamae, K, Ndwiga, L, Gichuki, PM, Okoyo, C, Kepha, S, Keitany, K, Kandie, R, Aricha, S, Kiplagat, R, Mwandawiro, C, Bejon, P, Snow, RW, Ochola-Oyier, LI

“…Background: To understand the emergence and spread of drug-resistant parasites in malaria-endemic areas, accurate assessment and monitoring of antimalarial drug resistance markers is critical. …”

Mortality rates among patients successfully treated for hepatitis C in the era of interferon-free antivirals: population based cohort study by Hamill, V, Wong, S, Benselin, J, Krajden, M, Hayes, PC, Mutimer, D, Yu, A, Dillon, JF, Gelson, W, Velásquez García, HA, Yeung, A, Johnson, P, Barclay, ST, Alvarez, M, Toyoda, H, Agarwal, K, Fraser, A, Bartlett, S, Aldersley, M, Bathgate, A, Binka, M, Richardson, P, Morling, JR, Ryder, SD, Barnes, E

“…The leading causes of death were drug related mortality (n=383, 24%), liver failure (n=286, 18%), and liver cancer (n=250, 16%). …”

Non-traditional security issues : securitisation of transnational crime in Asia by Laki, James

“…Transnational crime involving all forms of domestic crime that tranverse the international boundary with another one or more states have become a concern amongst all peoples of the Asia Pacific region. …”
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Association of current Schistosoma mansoni, Schistosoma japonicum, and Schistosoma mekongi infection status and intensity with periportal fibrosis: a systematic review and meta-ana... by Ewuzie, A, Wilburn, L, Thakrar, DB, Cheng, H, Reitzug, F, Roberts, N, Malouf, R, Chami, GF

“…Two reviewers independently screened abstracts and full-text reports for eligibility. A third reviewer was consulted in cases of disagreement. …”

Striking a gut-liver balance for the antidiabetic effects of metformin by Barroso, Emma, Montori-Grau, Marta, Wahli, Walter, Palomer, Xavier, Vázquez-Carrera, Manuel

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A P450BM3 toolkit For C-H activation synthesis by Ren, X

“…Successful applications include drug metabolism, drug fragment diversification, synthesis of flavour and fragrance compounds, steroid oxidation, late-stage functionalisation in total synthesis, and C–H amination. …”

CRISPR locus sequencing for Mycobacterium detection and differentiation by Zhen, Yashu

“…Mycobacterium tuberculosis Complex (MTBC) refers to a group of Mycobacterium species that sharing same ancestor and all can cause tuberculosis. As each MTBC specie also has lots of different strains, which related to drug-resistance and outbreak prevention, it is important to keep detecting and differentiating them clearly. …”
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Impact of pyridyl moieties on the inhibitory properties of prominent acyclic metal chelators against metallo-β-lactamase-producing Enterobacteriaceae : investigating the molecular... by Sosibo, Sphelele C., Somboro, Anou M., Amoako, Daniel G., Osei Sekyere, John, Bester, Linda A., Ngila, Jane C., Sun, Darren Delai, Kumalo, Hezekiel M.

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In silico screening of sugar alcohol compounds to inhibit viral matrix protein VP40 of Ebola virus by Nagarajan, Nagasundaram, Yapp, Edward Kien Yee, Le, Nguyen Quoc Khanh, Yeh, Hui-Yuan

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Improving access to pulmonary rehabilitation for patients with COPD treated for substance misuse in the London Borough of Islington by Narasimhan, Divya, Simpson, Jane, Stewart, Duncan

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Barriers and leverage points for seeing alcohol differently in integrated care systems in England: a senior stakeholder interview study by Madden, Mary, Stewart, Duncan, McCambridge, Jim

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Investigation of phenylpropanoid sucrose esters as antidiabetic compounds by Wong, Kathy Pooi Wen

“…Alpha glucosidase inhibitors (AGIs) are a class of anti-diabetic drug known for their effectiveness and safety. However, they are associated with gastrointestinal (GI) side-effects such as diarrhoea, nausea and flatulence. …”
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The treatment of malaria in pregnancy by Nosten, F, McGready, R

“…Studies are urgently needed to define the best therapeutic options and to develop new treatments, especially in Africa where drug resistance already compromises all strategies of control.…”

Blood brain barrier: a tissue engineered microfluidic chip by Musafargani, Sikkandhar, Mishra, Sachin, Gulyás, Miklós, Mahalakshmi, P., Archunan, Govindaraju, Padmanabhan, Parasuraman, Gulyás, Balázs

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Investigation of Synthetic Proteins Produced via Automated Fast-Flow Peptide Synthesis by Cowfer, Amanda Elizabeth

“…I will discuss the iterative steps my team took to vary both chemical and mechanical and control variables to improve per-coupling yield enough to enable access to full-length single-domain proteins. On this journey, we utilized test peptides to validate synthesis quality and later synthesized a suite of full-length single-domain biologically active proteins. …”
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