Transdermal Drug Delivery by Ong, Yuhui

“…As each drugs have different molecular properties, operation parameters are varied accordingly. …”
Get full text

Investigating viral glycosylation pathways for drug and vaccine development by Brun, J

“…</p> <p>The current COVID-19 pandemic has highlighted the urgent need for vaccines and antiviral drugs. The principal topic of my DPhil centres on addressing these needs for viral infection. …”

Deep learning methods for genome-based prediction of drug resistance in Mycobacterium tuberculosis by Wang, C

“…Recent years have seen a concerning rise in drug-resistant tuberculosis cases, calling for the development of new approaches for drug susceptibility testing. …”

A hydrophilic polyimidazolium antibiotic targeting the membranes of Gram-negative bacteria by Chen, Yahua, Yong, Melvin, Li, Ming, Si, Zhangyong, Koh, Chong Hui, Lau, Pearlyn, Chang, Yi Wei, Teo, Jeanette, Chan-Park, Mary B., Gan, Yunn-Hwen

“…The rise of MDR Gram-negative bacteria (GNB), especially those resistant to last-resort drugs such as carbapenems and colistin, is a global health risk and calls for increased efforts to discover new antimicrobial compounds. …”
Get full text

Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY) by Karadzas, M

“…These screens reveal antifungal drug targets, transporters responsible for drug uptake or efflux, as well as metabolic, signalling and trafficking pathways affecting antifungal susceptibility. …”

Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo... by Liu, Fang

“…In part II, my first project is the development of novel drug-loaded nanogels for pH sensitive drug release, which will be described in chapter 3. …”
Get full text

RES.10-001 Making Science and Engineering Pictures, Fall 2014 by Frankel, Felice C.

Get full text

Modular Titratable Polypills for Personalized Medicine and Simplification of Complex Medication Regimens by Karavasili, Christina, Babaee, Sahab, Kutty, Shruti, Chu, Jacqueline N., Min, Seokkee, Fitzgerald, Nina, Morimoto, Joshua, Inverardi, Nicoletta, Traverso, Giovanni

“…To fill the existing gap in drug dose personalization and simplification of complex medication regimens commonly encountered in the treatment of cardiovascular disease, tuberculosis, and tapering of corticosteroid therapy, a modular titratable polypill approach that simultaneously addresses both aspects is proposed. …”
Get full text

An analysis of heavy silicone oil treatment for inferior proliferative vitreoretinopathy by Hammer, M, Ie, A, Eibenberger, K, Auffarth, GU, Xue, K

“…The number of glaucoma drugs were increased in 45% of patients during Densiron tamponade. …”

An experimental and simulation study of chip transportation behaviour in gundrilling by Tnay, Guan Leong

“…From the experiments, terminal velocities of typical gun drill chips at different range of particle Reynolds number were determined to construct the unique drag curve. Based on the findings, a computational fluid dynamic (CFD) numerical model was developed to predict the lateral drag forces with respect to the particle Reynolds number. …”
Get full text

You Are the Placebo : Making Your Mind Matter / by Dispenza, Joe, author 656175, Hay House (Online service) 656169

“…Is it possible to heal by thought alone—without drugs or surgery? The truth is that it happens more often than you might expect. …”
Get full text

Effect of inflammation on apolipoprotein A-1(apoA-1) secretion by intestinal cells. by Yu, Kenneth.

“…This study has shown that ApoA-l secretion in intestinal cells is constitutive; however, the rate of apoA-l secretion is increased by as high as 5-times the constitutive secretion rate when the cells are exposed to anti-inflammatory drugs such as aspirin and paracetamol. In contrast, pro-inflammatory drugs such as lipopolysaccharides and endotoxin appeared to decrease intestinal secretion of apoA-1. …”
Get full text

Determination of operating point for a propulsive wing UAV using CFD by Chan, Chee Shuan

“…CFD simulations were performed using a 2D RANS k-ε turbulence model and the rotating flow was captured using the moving reference frame method. Lift and drag were obtained for different angle of attacks via a control volume analysis of CFD results. …”
Get full text

Please, let me go / by Spencer, Caitlin, author 656310, Brown, Linda Watson author 656311

“…From the age of 14, Caitlin was completely controlled, repeatedly raped, provided with alcohol, given drugs, sold and passed on to new gangs over and over again. …”

Settling velocity of a porous object by Muhammad Khalil Khaidir

“…In actual situations, particles found in wastewater which are commonly called flocs are porous which means that there are cavities within the particles that allow advection flow through it. …”
Get full text

Interfacial phenomena and biological recognition of mammalian cells on biomimetic materials by Chan, Vincent.

“…We intend to fill this gap by interrogating the biophysical events involved in membrane-polymer interaction, biological adhesion, tissue engineering and cellular fluid mechanics. …”
Get full text

CFD analysis of flow across adjacent buildings with concave roof structure using large-eddy simulation (LES) by Foo, Tze Jie

“…The software to be used is an open source CFD program called OpenFoam, which exposes the user to Linux kind of programming environment. …”
Get full text

Neutron emission studies from miniature and medium size plasma focus device by Singh, Rajdeep Raweet.

“…Although dense plasma focus devices have attracted the attention of scientific community since 1960’s as a copious source of fusion neutrons but in the recent years owing to spin-off in the applications of compact and portable table top neutron sources in wider domain, like noninvasive interrogation of explosives and narcotic drugs (by using Pulsed Fast/Thermal Neutron Analysis (PFTNA) technique), dark matter research, radioisotope production, medical neutron therapy and soil humidity measurements, there has been renewed interest across the globe for the development of sub-kilojoule range, low energy small plasma focus device (hereafter called ‘Miniature Plasma Focus i.e. …”
Get full text

Rationale and concerns for using JAK inhibitors in axial spondyloarthritis by Ahmed, S, Yesudian, R, Ubaide, H, Coates, LC

“…Treatment options have advanced over recent years and have become more targeted, including biologic treatments and, more recently, small molecule oral drugs called Janus kinase inhibitors. These newer agents have a rapid onset of action, can be taken orally and have efficacy in reducing inflammation across the whole spectrum of disease. …”

Integrate Traditional Chinese Medicine (TCM) into cognitive behavioural therapy to treat postpartum depression in Chinese culture contexts. by Han, Shuyu.

“…Furthermore, women are expected to provide breastfeed after delivery. Taking drugs such as antidepressants will be strongly believed it’s harmful to child. …”
Get full text