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bally » ball (Expand Search), sally (Expand Search), badly (Expand Search)
fill » film (Expand Search), fall (Expand Search), file (Expand Search)
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Nanosized silica particles for achiral drug separation
Published 2009“…It is widely recognized that the full potential of rapid chromatography can be realized with very small support particulates and tailor-made chiral stationary phase. …”
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Research Report -
2
18F-labelling of new chemotypes for drug discovery
Published 2016“…Finally, Chapter 5 gives full experimental procedures and characterisation data for all compounds.…”
Thesis -
3
Amplifying signals in the tumor microenvironment for drug development and diagnostics
Published 2024“…Leveraging advancements in high throughput screening and in deep learning, we contribute important tools for the effective design of conditional drugs that require the cleavage of a protease substrate to unleash drug cytotoxicity. …”
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Thesis -
4
Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases
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Journal Article -
5
Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy
Published 2024“…However, realizing the full potential of this approach requires a clear comprehension of the genetic dependencies underlying drug synergy. …”
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Article -
6
Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers
Published 2016“…The studies described in this thesis were undertaken to evaluate the application of paper spray mass spectrometry for direct analysis of small molecule drugs and biomarker in dried matrix spot samples. …”
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Thesis -
7
Modular Titratable Polypills for Personalized Medicine and Simplification of Complex Medication Regimens
Published 2024“…To fill the existing gap in drug dose personalization and simplification of complex medication regimens commonly encountered in the treatment of cardiovascular disease, tuberculosis, and tapering of corticosteroid therapy, a modular titratable polypill approach that simultaneously addresses both aspects is proposed. …”
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Article -
8
Interfacial phenomena and biological recognition of mammalian cells on biomimetic materials
Published 2008“…We intend to fill this gap by interrogating the biophysical events involved in membrane-polymer interaction, biological adhesion, tissue engineering and cellular fluid mechanics. …”
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Research Report -
9
Doxorubicin-loaded cell-derived nanovesicles: an alternative targeted approach for anti-tumor therapy
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Journal Article -
10
Understanding the viral protein structures of clinically relevant arboviruses and fragment-based screening for antivirals
Published 2020“…In recent years, antiviral drug discovery has increasingly relied on the use of high-resolution structural information of important viral proteins and have led to the development of potent inhibitors. …”
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Thesis-Doctor of Philosophy -
11
Design, simulation, and testing of a low cost laser micromachining system for flexible and rapid tissue-on-chip fabrication.
Published 2024“…With fabrication times of 6-8 minutes for small features and less than an hour for a full chip, our method represents a significant advancement in rapid prototyping capabilities. …”
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Thesis -
12
Optimising expression and purification of Dengue soluble E protein
Published 2023“…It offers insights into viral-host immune interactions. The full-length E protein is essential for vaccine design. …”
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Final Year Project (FYP) -
13
Ion doping behavior of stöber silica-nanosynthesis and application
Published 2016“…Besides, we can dope positive charged organic molecules inside silica nanoparticle, such as dyes, drugs, and so on. The above synthesis control is important to silica application in biosensors, drug delivery, catalysts, and battery. …”
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Thesis -
14
Association of current Schistosoma mansoni, Schistosoma japonicum, and Schistosoma mekongi infection status and intensity with periportal fibrosis: a systematic review and meta-ana...
Published 2024“…Two reviewers independently screened abstracts and full-text reports for eligibility. A third reviewer was consulted in cases of disagreement. …”
Journal article -
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Investigation of Synthetic Proteins Produced via Automated Fast-Flow Peptide Synthesis
Published 2024“…I will discuss the iterative steps my team took to vary both chemical and mechanical and control variables to improve per-coupling yield enough to enable access to full-length single-domain proteins. On this journey, we utilized test peptides to validate synthesis quality and later synthesized a suite of full-length single-domain biologically active proteins. …”
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Thesis -
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The influence of additives on the delivery of paclitaxel from bioresorbable PLGA films
Published 2013“…The study of the influences of additives on the drug delivery characteristics from PLGA thin films as a coating on angioplasty balloons was reported in this thesis. …”
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Thesis -
20
Evaluation of diabetic wound healing properties of moringa oleifera lam using in vitro and in vivo wound models
Published 2015“…Therefore, may serve as a lead in drug discovery for diabetic wound healing.…”
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Thesis